γ-Cyclodextrin - ≥90% cyclodextrin basis(HPLC), produced by Wacker Chemie AG, Burghausen, Germany , CAS No.17465-86-0

CAS: 17465-86-0 Cat. No.: C432227 Peso molecular: 1297.12 Beilstein Registry Number: 78740 Número EC: 241-482-4

GRADE & PURITY ≥90% cyclodextrin basis(HPLC), produced by Wacker Chemie AG, Burghausen, Germany

Synonyms

C-9140 | Cyclooctapentylose | NCGC00256143-01 | gamma cyclodextrin | gamma -Cyclodextrin | DTXSID5047033 | GAMMA CYCLODEXTRIN [USP-RS] | Ins-458 | CHEBI:495056 | GAMMA-CYCLODEXTRIN [FCC] | gamma-Cyclodextrin, Produced by Wacker Chemie AG, Burghausen, Germ

Storage

Room temperature

Descripción general

General Description

Gamma-cyclodextrin (γ-CD) is a cyclic α-1,4-glucan linked oligosaccharide that is widely used in the food and pharmaceutical industries. In drug delivery, γ-CD can be used as a complexing agent because it forms an inclusion complex with a drug molecule. The complex of cyclodextrin increases the aqueous solubility and dissolution rate of the drug, which is useful for the delivery of the medical agent to a biological system.

Application

γ-Cyclodextrin can be used as a precursor for the synthesis of: Octakis-(2,3-di- O -methyl-6- O -carboxymethyl)-γ-cyclodextrin sodium salt (ODMCM). ODMCM is used in capillary electrophoresis as a chiral resolving agent. Water-soluble cyclodextrin thioethers derivatives for the transportation of hydrophobic drugs.

Specifications

Sinónimos

C-9140 | Cyclooctapentylose | NCGC00256143-01 | gamma cyclodextrin | gamma -Cyclodextrin | DTXSID5047033 | GAMMA CYCLODEXTRIN [USP-RS] | Ins-458 | CHEBI:495056 | GAMMA-CYCLODEXTRIN [FCC] | gamma-Cyclodextrin, Produced by Wacker Chemie AG, Burghausen, Germ

Especificaciones y pureza

≥90% cyclodextrin basis(HPLC), produced by Wacker Chemie AG, Burghausen, Germany

Información jurídica

Cavasol is a registered trademark of Wacker Chemie AG

Condiciones de almacenamiento de almacenamiento

Room temperature

Pureza

≥90% cyclodextrin basis(HPLC)

Nombres e identificadores

• Sonrisas canónicas: C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(C(C8O)O)OC9C(OC(O2)C(C9O)O)CO)CO)CO)CO)CO)CO)CO)O)O)O
• IUPAC Name: (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,38R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56R)-5,10,15,20,25,30,35,40-octakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecol
• InChIKey: GDSRMADSINPKSL-HSEONFRVSA-N
• INCHI: 1S/C48H80O40/c49-1-9-33-17(57)25(65)41(73-9)82-34-10(2-50)75-43(27(67)19(34)59)84-36-12(4-52)77-45(29(69)21(36)61)86-38-14(6-54)79-47(31(71)23(38)63)88-40-16(8-56)80-48(32(72)24(40)64)87-39-15(7-55)78-46(30(70)22(39)62)85-37-13(5-53)76-44(28(68)20(37)60)83-35-11(3-51)74-42(81-33)26(66)18(35)58/h9-72H,1-8H2/t9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-/m1/s1
• Isómeros SMILES: C([C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]7[C@H](O[C@@H]([C@@H]([C@H]7O)O)O[C@@H]8[C@H](O[C@@H]([C@@H]([C@H]8O)O)O[C@@H]9[C@H](O[C@H](O2)[C@@H]([C@H]9O)O)CO)CO)CO)CO)CO)CO)CO)O)O)O
• WGK Alemania: 2
• Peso molecular: 1297.12
• Beilstein: 78740
• Reaxy-Rn: 5237049
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5237049&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Not available
• Direct Parent: Oligosaccharides
• Alternative Parents: Oxanes Secondary alcohols Polyols Oxacyclic compounds Acetals Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Oligosaccharide - Oxane - Secondary alcohol - Oxacycle - Organoheterocyclic compound - Polyol - Acetal - Hydrocarbon derivative - Primary alcohol - Alcohol - Aliphatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as oligosaccharides. These are carbohydrates made up of 3 to 10 monosaccharide units linked to each other through glycosidic bonds.
• External Descriptors: cyclodextrin

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción

Propiedades químicas y físicas

• Rotación específica [α]: 178° (C=1,H2O)
• Punto de fusión (°C): 267°C
• Peso molecular: 1297.100 g/mol
• XLogP3: -17.200
• Hydrogen Bond Donor Count: 24
• Hydrogen Bond Acceptor Count: 40
• Rotatable Bond Count: 8
• Exact Mass: 1296.42 Da
• Monoisotopic Mass: 1296.42 Da
• Topological Polar Surface Area: 633.000 Ų
• Heavy Atom Count: 88
• Formal Charge: 0
• Complexity: 1720.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 40
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

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53. Shu Huan Ren, Shi Gang Liu, Yu Ling, Nian Bing Li, Hong Qun Luo.  (2019)  Facile method for iodide ion detection via the fluorescence decrease of dihydrolipoic acid/beta-cyclodextrin protected Ag nanoclusters.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:30639913] [10.1016/j.saa.2019.01.009]

54. Haoran Fan, Jinpeng Wang, Qingran Meng, Zhengyu Jin.  (2018)  Monodisperse hollow-shell structured molecularly imprinted polymers for photocontrolled extraction α-cyclodextrin from complex samples.  FOOD CHEMISTRY,      [PMID:30658735] [10.1016/j.foodchem.2018.12.084]

55. Chuanhui Huang, Yujie Wang, Qiao Huang, Yu He, Lan Zhang.  (2018)  Magnetic γ-cyclodextrin polymer with compatible cavity promote the magnetic solid-phase extraction of microcystins in water samples.  ANALYTICA CHIMICA ACTA,      [PMID:30712592] [10.1016/j.aca.2018.12.028]

56. Shu Xiong, Sheng Xu, Sui Zhang, Anny Phommachanh, Yan Wang.  (2018)  Highly permeable and antifouling TFC FO membrane prepared with CD-EDA monomer for protein enrichment.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2018.11.012]

57. Jianyi Xu, Yilin Ma, Tingting Yu, Dan Zhu.  (2018)  Quantitative assessment of optical clearing methods in various intact mouse organs.  Journal of Biophotonics,  12  (2): (e201800134).  [PMID:30318789] [10.1002/jbio.201800134]

58. Le Chen, Dan-Dan Zhu, Guo-Jian Ji, Sheng Yuan, Jun-Feng Qian, Ming-Yang He, Qun Chen, Zhi-Hui Zhang.  (2018)  Efficient adsorption separation of xylene isomers using a facilely fabricated cyclodextrin-based metal–organic framework.  JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,  93  (10): (2898-2905).  [PMID:] [10.1002/jctb.5644]

59. Xiangying Yu, Man-Chu Chau, Wai Kit Tang, Chi-Kit Siu, Zhong-Ping Yao.  (2018)  Self-Assembled Binuclear Cu(II)–Histidine Complex for Absolute Configuration and Enantiomeric Excess Determination of Naproxen by Tandem Mass Spectrometry.  ANALYTICAL CHEMISTRY,      [PMID:29455521] [10.1021/acs.analchem.7b05407]

60. Zhen Hu, Cheng Wang, Feng Zhao, Xirong Xu, Shuhong Wang, Long Yu, Dayu Zhang, Yudong Huang.  (2017)  Fabrication of a graphene/C60 nanohybrid via γ-cyclodextrin host–guest chemistry for photodynamic and photothermal therapy.  Nanoscale,  9  (25): (8825-8833).  [PMID:28632263] [10.1039/C7NR02922E]

61. Feifei Gong, Huaxin Yang, Wen Sun, Junzi Cao, Wanhui Liu.  (2015)  Development and validation of a micellar electrokinetic capillary chromatography method for the determination of goserelin and related substances.  ELECTROPHORESIS,  37  (4): (623-629).  [PMID:26635325] [10.1002/elps.201500328]

62. Sulong Xiao, Longlong Si, Zhenyu Tian, Pingxuan Jiao, Zibo Fan, Kun Meng, Xiaoshu Zhou, Han Wang, Renyang Xu, Xu Han, Ge Fu, Yongmin Zhang, Lihe Zhang, Demin Zhou.  (2015)  Pentacyclic triterpenes grafted on CD cores to interfere with influenza virus entry: A dramatic multivalent effect.  BIOMATERIALS,      [PMID:26686050] [10.1016/j.biomaterials.2015.11.034]

63. Xun Zhang, Yuxia Gao, Yuan Lin, Jun Hu, Yong Ju.  (2015)  Photo-induced conversion from supramolecular to covalently linked polymers based on anthracene-appended amphiphiles.  Polymer Chemistry,  6  (22): (4162-4166).  [PMID:] [10.1039/C5PY00476D]

64. Xiaoyu Mu, Li Qi, Juan Qiao, Xinzheng Yang, Huimin Ma.  (2014)  Enantioseparation of dansyl amino acids and dipeptides by chiral ligand exchange capillary electrophoresis based on Zn(II)-l-hydroxyproline complexes coordinating with γ-cyclodextrins.  ANALYTICA CHIMICA ACTA,      [PMID:25220143] [10.1016/j.aca.2014.07.022]

65. Bin Yang, Huizhen Jia, Xuli Wang, Si Chen, Xianzheng Zhang, Renxi Zhuo, Jun Feng.  (2013)  Self-Assembled Vehicle Construction via Boronic Acid Coupling and Host–Guest Interaction for Serum-Tolerant DNA Transport and pH-Responsive Drug Delivery.  Advanced Healthcare Materials,  3  (4): (596-608).  [PMID:23983152] [10.1002/adhm.201300162]

66. Xin Guo, Xiangxiang Jia, Jiaojiao Du, Longqiang Xiao, Feifei Li, Liqiong Liao, Lijian Liu.  (2013)  Host–guest chemistry of cyclodextrin carbamates and cellulose derivatives in aqueous solution.  CARBOHYDRATE POLYMERS,      [PMID:23987437] [10.1016/j.carbpol.2013.06.075]

67. Huaiting Pang, Yimin Wu, Qianlan Tao, Yewen Xiao, Wei Ji, Linlin Li, Hualin Wang.  (2024)  Active cellulose acetate/purple sweet potato anthocyanins@cyclodextrin metal-organic framework/eugenol colorimetric film for pork preservation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38428771] [10.1016/j.ijbiomac.2024.130523]

68. Yanli Zhao, Ziqi Cao, Yanxiang Liang, Zhichen Liang, Keyin Ling, Feiyan Zhou, Changsheng Guo, Yao Qian, Pengbi Liu, Xi Liu, Chunguang Wang, Mengchen Zhang, Qinglei Zhang.  (2025)  Aligned amino-functionalized γ-cyclodextrin nanofiltration membrane via customized interfacial polymerization for precise Li+/Mg2+ separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.132092]

69. Mengmeng Zhang, Jingbo Liu, Yiding Yu, Wenshuo Ren, Rui Yuan, Xuanting Liu, Xiaomin Shang, Zhiyang Du, Meng-Lei Xu, Ting Zhang.  (2024)  Alleviates effects of γ-cyclodextrin/genistein inclusion complex on oxidative stress injury induced by organic hydrogen peroxide in PC12 cells via Nrf2/GPx4 signaling pathway.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.105631]

70. Yuhong Li, Mengting Zhang, Yutian Huang, Pengcheng Zhao, Jinyao Zhao, Junjie Fei, Yixi Xie.  (2024)  An ultrasensitive 4-aminophenol electrochemical sensors based on zinc and nitrogen-doped γ-cyclodextrin composites.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.109905]

71. Guodong Zhang, Zheng-Zhi Yin, Xiaoming Zuo, Haiying Chen, Guochun Chen, Jun Gao, Yong Kong.  (2024)  Carboxymethyl potato starch hydrogels encapsulated cyclodextrin metal-organic frameworks for enantioselective loading of S-naproxen and its programmed release.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38340930] [10.1016/j.ijbiomac.2024.130013]

72. Caiyun Liu, Xibu Wei, Zengshuai Zhang, Qianqian Miao, Mario Prejanò, Tiziana Marino, Yongsheng Tao, Yunkui Li.  (2025)  Color protection, aroma enhancement and sensory improvement of red wines: Comparison of pre-fermentation additions of cyclodextrins and polysaccharides.  FOOD CHEMISTRY,      [PMID:40031134] [10.1016/j.foodchem.2025.143432]

73. Jiateng Ma, Chuang Liu, Jiali Li, Zhiquan An, Bihong Zhang, Wenjun Hong, Cheng Ye, Minjie Li, Liang-Hong Guo.  (2025)  Colorimetric visualization detection of perfluorooctanoic acid based on host–guest interactions with cyclodextrin-modified gold nanoparticles.  Environmental Science-Nano,      [PMID:] [10.1039/D4EN01096E]

74. Shuai Liu, Yuzhu Xiong, Fuping Dong.  (2024)  Cyclodextrin metal–organic framework@SiO2 nanocomposites for poorly soluble drug loading and release.  RSC Advances,  14  (43): (31868-31876).  [PMID:39380653] [10.1039/D4RA04935G]

75. Yanhui Zhang, Hongbo Li, Xiaoqin Hai, Xiaoli Guo, Xin Di.  (2024)  Designing green and recyclable switchable supramolecular deep eutectic solvents for efficient extraction of flavonoids from Scutellariae Radix and mechanism exploration.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:38879980] [10.1016/j.chroma.2024.465084]

76. Jing Yi, Shuqi Zhang, Xuanxuan Yuan, Zhilong Zhang, Zhongguo Shan, Haihua Wang.  (2024)  Development of multifunctional zein-based films engineered with gallic acid and Ag NPs loaded γ-CD-MOFs for pork preservation.  Food Packaging and Shelf Life,      [PMID:] [10.1016/j.fpsl.2024.101352]

77. Jun Chen, Meng Li, Qianru Gao, Huabing Yang, Tianxiang Zhu, Xiaojuan Zou, Baifei Hu, Hongtao Liu.  (2024)  Dihydromyricetin, a flavonoid from vine tea (Ampelopsis grossedentata) provides hepatoprotection by modulating gut microbiota-mediated bile acid homeostasis.  Journal of Agriculture and Food Research,      [PMID:] [10.1016/j.jafr.2024.101376]

78. Jiaqi Ding, Xiaoxiao Li, Zhengyu Jin, Maher Abou Hachem, Yuxiang Bai.  (2024)  Efficient glycosylation of polyphenols via dynamic complexation of cyclodextrin and synchronous coupling reaction with cyclodextrin glycosyltransferase in water.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39353521] [10.1016/j.ijbiomac.2024.136065]

79. Jianglong Du, Yanqiu Chu, Yinghua Yan, Zhenhua Li, Chuan-Fan Ding.  (2025)  Elucidation of molecular recognition of catecholamine enantiomer by cyclodextrin combined ion mobility spectrometry and theoretical calculation.  CARBOHYDRATE POLYMERS,      [PMID:39914953] [10.1016/j.carbpol.2025.123260]

80. Meng Li, Dongxia Hu, Dian Zhang, Guangya Xu, Di Wu, Chengcheng Gao, Linghan Meng, Xiao Feng, Weiwei Cheng, Zhenjiong Wang, Yuling Yang, Xiaozhi Tang.  (2025)  Encapsulation of oleanolic acid into cyclodextrin metal-organic frameworks by co-crystallization: Preparation, structure characterization and its effect on a zebrafish larva NAFLD model.  FOOD RESEARCH INTERNATIONAL,      [PMID:39986782] [10.1016/j.foodres.2025.115936]

81. Yuxiao Hu, Zhijian Tan.  (2025)  Enhanced ammonia-sensitive intelligent films based on a metal-organic framework for accurate shrimp freshness monitoring.  FOOD CHEMISTRY,      [PMID:39798360] [10.1016/j.foodchem.2025.142805]

82. Jingbo Liu, Yang Liu, Shanglin Li, LongJiang Tian, Yajuan Li, Chunmei Liu, Sitong Ma, Ting Zhang, Meng Yang, Zhiyang Du.  (2025)  Fructose-modified chitosan-based coassemblies reinforced oral bioavailability of egg white oligopeptides and curcumin via glucose transporter 2-oriented transcytosis and preferable mucus permeation.  FOOD RESEARCH INTERNATIONAL,      [PMID:40058919] [10.1016/j.foodres.2025.116065]

83. Jun-Feng Feng, Jia-Xin Wang, Wen-Tao Liu, Shu-Ting Fan, Dong-Lin Guo, Min Tan, Bang-Jing Li, Kun Guo, Sheng Zhang.  (2024)  Highly Stretchable Liquid-Metal/Elastomeric Foam Based on a Slidable Double Network for Absorption-Dominated Electromagnetic Interference Shielding.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.4c00200]

84. Yue Dai, Xiaoxiao Li, Zhengyu Jin, Yuxiang Bai.  (2024)  Improving cyclodextrin yield via retarding retrogradation of debranched starches during the preparation of cyclodextrin with cyclodextrin glycosyltransferase and pullulanase.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.104067]

85. Jian Yu, Ling Zhang, Liguo Shen, Renjie Li, Dieling Zhao, Hongjun Lin, Yanchao Xu, Yang Jiao.  (2024)  In situ grown cyclodextrin metal-organic framework nanoparticles templated stripe nano-wrinkled polyamide nanofiltration membranes for efficient desalination and antibiotic removal.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2024.122413]

86. Feng-Yang Chen, Xia Tang, Yuan Zhu, Hang Li, Baoru Yang, Qinghai Sheng, Qing‐Sheng Zhao.  (2025)  Inclusion complexation of catechins by hyperbranched cyclodextrin: Preparation, characterization, stability, antioxidant and antimicrobial properties.  NEW JOURNAL OF CHEMISTRY,      [PMID:] [10.1039/D4NJ04443F]

87. Yan Chen, Li Liao, Jin Liu, Hongxia Gao, Xing Chen, Lexiang Zhang, Liqiang Zou.  (2025)  Incorporation of vanillin complex microparticles into bread for enhanced antibacterial activity and extended shelf-life.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.117518]

88. Zonghan Wang, Yingchen Fan, Ying Luo, Chao Guo, Yuanyuan Hu, Xiaoming Guo, Dayong Zhou, Beiwei Zhu.  (2025)  Mechanisms of epigallocatechin-3-gallate-loaded metal−organic framework in preventing oxidative degradation of shrimp (Litopenaeus vannamei) surimi gel.  FOOD CHEMISTRY,      [PMID:39864174] [10.1016/j.foodchem.2025.143036]

89. Meiqi Xu, Junwei Liu, Jianming Yu, Jingwen Wang, Hui Li, Ting Zhong, Yanli Hao, Zhuoyue Li, Jingru Wang, Xu Huang, Hui Wang, Yubo Tian, Heng Zhao, Qingchao Wei, Xuan Zhang.  (2024)  Methyl-β-cyclodextrin Enhances Tumor Cellular Uptake and Accumulation of α-Linolenic Acid–Paclitaxel Conjugate Nanoparticles.  MOLECULAR PHARMACEUTICS,      [PMID:39495317] [10.1021/acs.molpharmaceut.4c00190]

90. Dehua Wang, Biqian Wei, Yi Zhang, Tongxin Xie, Jing Yu, Yong Xue, Biao Kong, Changhu Xue, Qingjuan Tang.  (2024)  Multifunctional curcumin/γ-cyclodextrin/sodium chloride complex: A strategy for salt reduction, flavor enhancement, and antimicrobial activity in low-sodium foods.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2024.117085]

91. Hailian Wu, Xiaoxia Jiang, Zishu Dong, Qimeng Fan, Jia Huang, Hongning Liu, Lihua Chen, Zhe Li, Liangshan Ming.  (2024)  New insights into the influence of encapsulation materials on the feasibility of ultrasonic-assisted encapsulation of Mosla chinensis essential oil.  ULTRASONICS SONOCHEMISTRY,      [PMID:38310739] [10.1016/j.ultsonch.2024.106787]

92. Shuqi Zhang, Jing Yi, Zhilong Zhang, Xuanxuan Yuan, Zhongguo Shan, Haihua Wang.  (2024)  Preparation of zein active films with antimicrobial and antioxidant properties by incorporating gallic acid loaded γ-CD-MOF for pork preservation.  FOOD CONTROL,      [PMID:] [10.1016/j.foodcont.2024.110822]

93. Qinfei Ke, Jiamin Zhu, Dongdong Su, Fei Pan, Qingran Meng, Xingran Kou.  (2024)  Preparation, physicochemical characterization, and computational studies of aldehyde aroma compounds/cyclodextrin inclusion complexes.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2024.118245]

94. Meng Yang, Jingbo Liu, Chunmei Liu, Hui Zhang, Shanglin Li, Ting Zhang, Zhipeng Yu, Xiwen Chi, Zhihui Zhang, Zhiyang Du.  (2025)  Programmable Food-Derived Peptide Coassembly Strategies for Boosting Targeted Colitis Therapy by Enhancing Oral Bioavailability and Restoring Gut Microenvironment Homeostasis.  ACS Nano,      [PMID:39745599] [10.1021/acsnano.4c11108]

95. Wangfei Yu, Guannan Wang, Huizhi Chen, Honglei Mu, Ben Niu, Yanchao Han, Lishu Wang, Hangjun Chen, Haiyan Gao.  (2025)  Sustained antimicrobial polymer film from γ-CD-MOF humidity switch for fruit and vegetable preservation.  FOOD CHEMISTRY,      [PMID:40086383] [10.1016/j.foodchem.2025.143856]

96. Xinyi Fan, Yuexin Bao, Yanhong Chen, Xiaohong Wang, Stephen L. W. On, Jia Wang.  (2024)  Synthesis of β-Cyclodextrin@gold Nanoparticles and Its Application on Colorimetric Assays for Ascorbic Acid and Salmonella Based on Peroxidase-like Activities.  Biosensors-Basel,  14  (4): (169).  [PMID:38667162] [10.3390/bios14040169]

97. Xiaopeng Peng, Jianglong Du, Long Chen, Keqi Ye, Jiacheng Ye, Yinghua Yan, Chuan-Fan Ding.  (2025)  The Identification and Quantification of the Positional Isomers of Dimethylbipyridine by Ion Mobility Mass Spectrometry Analysis of Their Gas Phase Complexes.  RAPID COMMUNICATIONS IN MASS SPECTROMETRY,  39  (10): (e10003).  [PMID:40007178] [10.1002/rcm.10003]

98. Caijie Yuan, Yaxin Ye, Enling Hu, Ruiqi Xie, Bitao Lu, Kun Yu, Weiwei Ding, Wenyi Wang, Guangqian Lan, Fei Lu.  (2024)  Thrombotic microenvironment responsive crosslinking cyclodextrin metal-organic framework nanocarriers for precise targeting and thrombolysis.  CARBOHYDRATE POLYMERS,      [PMID:38553243] [10.1016/j.carbpol.2024.122058]

99. Tiansheng Gao, Yuqian Yang, Wenzhong Ma, Xiaoyi Zhang, Haicun Yang, Qiuyan Bi, Jing Zhong, Hideto Matsuyama.  (2025)  Quaternary ammonium-functionalized γ-cyclodextrin tailored polyamide nanofiltration membranes for highly selective Li+/Mg2+ separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.134161]

100. Yinghong Wang, Ping Xiong, Wei Yang, Zhitong Zhang, Xiaoling Xu, Liming Yang, Huiji Xiao, Kai Zhang, Zhenzhou Wang, Wei Zhang, Xubiao Luo.  (2025)  A synergistic strategy for efficient Li+/Mg2+ separation based on γ-CD cavity regulation and histidine electrostatic repulsion.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.134529]

101. Yanyan Guo, Yingxue Yue, Huanhuan Wang, Ziyi Zhong, Bin Chen, Luan Shu, Jing Wang, Zhenhai Zhang.  (2025)  Hydroxypropyl-β-cyclodextrin inclusion complex improves the percutaneous therapeutic effect of eugenol on psoriasis mice.  EUROPEAN JOURNAL OF PHARMACOLOGY,      [PMID:40618981] [10.1016/j.ejphar.2025.177921]

102. Haojie Qiu, Jingyan Zhu, Kaikai Zhang, Xinnan Wang, Yaoting Chu, Feng Zhang, Xuefeng Yang.  (2025)  Dual Drug-Loaded Hyaluronate-Based Self-Adaptable Hydrogel for Diabetic Infected Wound Healing.  BIOMACROMOLECULES,      [PMID:40845349] [10.1021/acs.biomac.5c00712]

103. Jiongcheng Lu, Jiawei Lin, Ran Chen, Qian Sun, Zhenxing Wang, Wen Huang, Lili Cai, Xuetao Shi, Meng Zhang, Kaojin Wang, Lin Wang, Yong-Guang Jia, Xiaoxia Zhu.  (2025)  3D Printing of α-Amylase-Illuminated Fluorescent Devices for Dynamic Information Storage and Encryption.  Aggregate,      [PMID:] [10.1002/agt2.70153]

104. Maowa Zhang, Haiqing Hao, Chenxi Shi, Chongchong Chen, Guoli Zhou, Jingtao Wang, Yijun Cao, Xiangke Han.  (2023)  Bis-terpyridine imprinted nanocage in the confined two-dimensional lamellar membrane for selective adsorption of Nd(III).  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2023.123095]

105. Zhicheng Li, Yanan Sun, Xiaodan Pan, Tong Gao, Ting He, Chun Chen, Bin Zhang, Xiong Fu, Qiang Huang.  (2022)  Controlled Release of Thymol by Cyclodextrin Metal-Organic Frameworks for Preservation of Cherry Tomatoes.  Foods,  11  (23): (3818).  [PMID:36496626] [10.3390/foods11233818]

106. Shutong Yang, Liancheng Gu, Fangling Wu, Xinhua Dai, Fuxing Xu, Qiaoyu Li, Xiang Fang, Shaoning Yu, Chuan-Fan Ding.  (2022)  The chirality determination of amino acids by forming complexes with cyclodextrins and metal ions using ion mobility spectrometry, and a DFT calculation.  TALANTA,      [PMID:35272154] [10.1016/j.talanta.2022.123363]

107. Bo Zhang, Hongwen Chen, Liming Jiang, Youqing Shen, Dan Zhao, Zhuxian Zhou.  (2021)  A breathing A4 paper by in situ growth of green metal–organic frameworks for air freshening and cleaning.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2021.12.003]

108. Cai Zuo, Hongping Li, Gong Chen, Jun Yang, Zhixin Xu, Zhigang Xue.  (2021)  Fabrication of Elastic Cyclodextrin-Based Triblock Polymer Electrolytes for All-Solid-State Lithium Metal Batteries.  ACS Applied Energy Materials,      [PMID:] [10.1021/acsaem.1c01625]

109. Hui Wang, Naimin Shao, Shengnan Qiao, Yiyun Cheng.  (2012)  Host–Guest Chemistry of Dendrimer–Cyclodextrin Conjugates: Selective Encapsulations of Guests within Dendrimer or Cyclodextrin Cavities Revealed by NOE NMR Techniques.  JOURNAL OF PHYSICAL CHEMISTRY B,      [PMID:22934608] [10.1021/jp3062916]

110. Qingjie Li, Jinhao Yan, Wenlong Jiang, Yunpeng Zhang, Peng Gao, Longxiang Tao, Jun Yin.  (2024)  Asymmetric Cyclodextrin-Dimer-Involved Nanoassemblies by Selective Host–Guest Interactions: Concentration-Dependent Morphology Evolution and Light-Regulated Biomedical Applications.  BIOMACROMOLECULES,      [PMID:38241024] [10.1021/acs.biomac.3c01067]

111. Lilin Fang, Peng Cui, Dongni Liu, Xiaosi Sun, Hao Ren, Hanyu Zhang, Yan Huang, Wenshuai Zhu, Zhichang Liu.  (2024)  Construction of shaped adsorbent based on cyclodextrin organic polymers for removal of polycyclic aromatic hydrocarbons.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.130468]

112. Chao Wang, Yujia Lu, Peijuan Chu, Tengfei He, Lijia Liu, Chunhong Zhang.  (2024)  Design of intrinsically antibacterial thin film composite membrane based on natural material for efficient molecular sieving.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.129798]

113. Yun-Dong Yin, Lei Yang, Xi-Tong Song, Jun Hu, Fang-Fang Chen, Ming Xu, Zhi-Yuan Gu.  (2024)  Determination of Acetylamantadine by γ-Cyclodextrin-Assisted α-HL Nanopore for Potential Cancer Prediagnosis.  ANALYTICAL CHEMISTRY,      [PMID:38738931] [10.1021/acs.analchem.3c04986]

114. Junhao Wang, Rongning Liang, Wei Qin.  (2024)  Improvement of the selectivity of a molecularly imprinted polymer-based potentiometric sensor by using a specific functional monomer.  ANALYTICA CHIMICA ACTA,      [PMID:38462336] [10.1016/j.aca.2024.342412]

115. Mingming Zhao, Huizi Lu, Zhiheng You, Huayun Chen, Xiao Wang, Yaqing Zhang, Yixian Wang.  (2024)  Olfactory Visualization Sensing Array Made with CelluMOFs to Predict Fruit Ripeness Using Deep Learning.  ACS Applied Materials & Interfaces,      [PMID:39403818] [10.1021/acsami.4c09402]

116. Zhongwen Luo, Wenchao Ye, Feng Long, Wenlang Liang, Yongxiang Leng.  (2024)  PPDA hybrid: a flexible and biocompatible platform for supercapacitor and strain sensing applications.  Journal of Materials Chemistry C,      [PMID:] [10.1039/D4TC00894D]

117. Naisheng Wu, Fangling Wu, Sisi He, Jia Wang, Huiqing Ding, Chuan-Fan Ding.  (2025)  Molecular-Level Insights into TIMS-MS Separation of α/β-Estradiol Isomers: Synergistic Effects of Cyclodextrins and Metal Ions.  ANALYTICAL CHEMISTRY,      [PMID:40970670] [10.1021/acs.analchem.5c03830]

118. Zou Ying, Zhang Manli, Zhou Dongdong, Chi Chaoxian, Wu Fangling, Ding Chuan-Fan.  (2025)  Identification and characterization of chiral vitamin C using ion mobility and theoretical calculation.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,      [PMID:40192766] [10.1007/s00216-025-05855-7]

119. Zhuo Li, Zhengnan Guo, Zhengmeng Yang, Boguang Yang, Yuan Hu, Xian Xie, Zhixian Zong, Zekun Chen, Kunyu Zhang, Pengchao Zhao, Gang Li, Xuefeng Yang, Liming Bian.  (2025)  Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration.  Cell Reports,      [PMID:40272981] [10.1016/j.celrep.2025.115611]

120. Long Chen, Jianglong Du, Xiaopeng Peng, Jiacheng Ye, Keqi Ye, Yinghua Yan, Chuan-Fan Ding.  (2025)  Discrimination of Lutidine Isomers by Ion Mobility Spectrometry Using α-Cyclodextrin and Metal Ions.  ANALYTICAL LETTERS,      [PMID:] [10.1080/00032719.2025.2494743]

121. Pengpeng Guan, Caijie Yuan, Jiali Li, Zhou Wen, Enling Hu, Guangqian Lan, Bowen Cheng, Yinggui Huang, Fei Lu.  (2025)  Multifunctional magnetic MOF under cover of erythrocytes for ROS scavenging and magnetic hyperthermia thrombolysis.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.163939]

122. Jinqiu Liu, Bingxue Jiang, Yaoguang Chang, Yanchao Wang, Changhu Xue.  (2025)  Establishment of a novel refinement workflow for oligopeptides containing branched-chain amino acids with cyclodextrins.  FOOD CHEMISTRY,      [PMID:40409084] [10.1016/j.foodchem.2025.144732]

123. Jiaqi Ding, Xiaoxiao Li, Zhengyu Jin, Birte Svensson, Yuxiang Bai.  (2025)  Regulating the rate-limiting step of cyclodextrin glycosyltransferase glycosylation reaction for efficient production of glycosylated polyphenols.  BIORESOURCE TECHNOLOGY,      [PMID:40441452] [10.1016/j.biortech.2025.132727]

124. Haiyan Li, Xiao Zhang, Hongmei Luo, Jieling Chen, Qilin Huang.  (2025)  Edible γ-cyclodextrin metal–organic frameworks constructed for adsorbing saturated and unsaturated aldehydes to remove off-odors in surimi.  FOOD CHEMISTRY,      [PMID:40479984] [10.1016/j.foodchem.2025.145003]

125. Xue Wang, Lu Liu, Di Wu, Yuxin Hu, Hongzhuo Liu, Yizhou Sun, Guangqi Yan.  (2025)  Dexamethasone prodrug cyclodextrin aggregates effectively alleviate experimental autoimmune uveitis.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:40554951] [10.1016/j.colsurfb.2025.114889]

126. Chao Wang, Peijuan Chu, Tengfei He, Cheng Yi, Yue Yao, Lijia Liu, Chunhong Zhang.  (2025)  Natural product flavonoid of naringenin based thin-film composite polyester membranes preparation for antibiotic separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.134123]

127. Yanxue Si, Ruitao Cha, Pai Zhang, Fengshan Zhou, Wenbing Yuan, Xingyu Jiang.  (2025)  CD-MOF Based pH/ROS Sensitive 5-ASA Delivery System for Ulcerative Colitis Therapy.  Advanced Healthcare Materials,      [PMID:40545915] [10.1002/adhm.202501160]

128. Xiaoling Xie, Jingyuan Tian, Junying Wu, Ruijie Guo, Jie Zhang, Dongsheng Fu, Huifang Wang, Baolong Niu, Hong Yan.  (2025)  Polylactic Acid/ Poly(Butylene Adipate-Co-Terephthalate) Packing Films Doped with Novel Antimicrobial Agent CuO@γ-CD-MOFs.  ChemistrySelect,  10  (23): (e02743).  [PMID:] [10.1002/slct.202402743]

129. Liping Xu, Dandan Sha, Rongfan Ren, Hongli Li, David Da Yong Chen.  (2025)  Methylation in ambient ion source enables direct isomer differentiation of oligosaccharides by tandem mass spectrometry.  CARBOHYDRATE POLYMERS,      [PMID:41320349] [10.1016/j.carbpol.2025.124493]

130. Bowen Zou, Junwei Zhang, Xiaohan Zheng, Xiaokang Na, Ming Du, Chao Wu.  (2025)  Dual-function dextrin modulators in protein-rich matrices: Controlled aggregation for tailored fluid-gel transitions under thermal processing.  FOOD RESEARCH INTERNATIONAL,      [PMID:41271338] [10.1016/j.foodres.2025.117726]

131. Rongkai Cui, Minlei Yin, Xiaoyan Chen, Xiaoyu Lou, Chen Yang, Ting Qiu, Jie Chen.  (2025)  Efficient separation of 1,5-dimethyl-2-pyrrolidone from N-methylpyrrolidone enabled by pore confinement.  Industrial Chemistry & Materials,      [PMID:] [10.1039/D5IM00266D]

132. Wenfei Wang, Menglu Duan, Fei Li, Yanhui He, Runze Li, Qinhui He, Yuan Deng, Xiaofang Zhang, Jiao Li.  (2025)  In silico prediction of the formation, solubilization, and stabilization of a cyclodextrin-based ternary complex of ivermectin using long-timescale molecular dynamics simulations.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2025.128993]

133. Xuan Wang, Xu Meng, Tao Liang, Jiachun Song, Kamal Eldin Afaf, Hong Duan, Lingyan Zheng, Gang Chen.  (2025)  Development of γ-CD-MOF/Chitosan platform with sustained release capacity for food preservation.  FOOD CHEMISTRY,      [PMID:41435679] [10.1016/j.foodchem.2025.147458]

134. Hengxiu Wang, Hongchen Wang, Yue Yang, Tianming Wang, Changzhong Wang, Daqiang Wu, Caixia Zheng, Wenfan Wei.  (2025)  Berberine Suppresses Pathogenic Fungus Aspergillus fumigatus Hyphal Growth via Mitochondrial Fragmentation-Induced ROS Elevation and Hog1-MAPK Activation.  ACS Infectious Diseases,      [PMID:41358602] [10.1021/acsinfecdis.5c00749]

135. Zu-E Hu, Fu-Zhong Zhang, Minfeng Zeng, Ye-Tao Zhang, Jing Li, Yu-Ting Che, Jun-Feng Feng, Bang-Jing Li, Sheng Zhang.  (2025)  Inhalable Food-Grade MOFs Loaded Gas Messenger for Acute Lung Injury Treatment by Pulmonary Delivery.  ACS Applied Materials & Interfaces,      [PMID:41378492] [10.1021/acsami.5c20962]

136. Xinyao Quan, Jiajia Ma, Lingxiang Sun, Guili Huang, Siyao Sui, Haocong Li, Qianshuo Shao, Su Yan, Yuning Wang, Xiaoqing Wang.  (2025)  Enhanced Functional Properties of Chitosan Films Incorporated With Proanthocyanidins/Cinnamaldehyde/γ-Cyclodextrin Microcapsules for Citrus Fruit Preservation.  JOURNAL OF FOOD PROCESSING AND PRESERVATION,  2025  (1): (7504108).  [PMID:] [10.1155/jfpp/7504108]

137. Haiyan Li, Hongmei Luo, Jieling Chen, Qilin Huang.  (2025)  Potassium benzoate-cyclodextrin metal-organic frameworks with multi-dimensional cavities: An adsorbent for removing aldehyde fishy odorants in aquatic products.  FOOD RESEARCH INTERNATIONAL,      [PMID:41539771] [10.1016/j.foodres.2025.118187]

138. Gui Xinchen, Chen Yaozhong, Cao Shihai, Yu Yadong.  (2025)  Use zein/chitosan active packaging films containing curcumin and γ-cyclodextrin metal-organic frameworks to preserve strawberry.  Discover Food,  5  (1): (428).  [PMID:] [10.1007/s44187-025-00722-x]

139. Jiachuan Chen, Jiaming Fan, Kefeng Liu, Junchao Li, Qixiu Dong, Guihua Yang.  (2025)  A sustainable superhydrophobic paper enabled by CD-MOF/PDMS synergistic engineering for highly efficient oil/water separation.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2025.122447]

140. Xueqian Sun, Ziyu Qu, Di Zhang, Chuan-Fan Ding, Fangling Wu.  (2026)  Structural elucidation and quantitative analysis of cinnamic acid derivatives using TIMS-MS, cyclodextrin adducts, and computational chemistry.  FOOD CHEMISTRY,      [PMID:41650776] [10.1016/j.foodchem.2026.148247]

141. Jinquan Huang, Xiaowa Gao, Jiayan Luo, Jiwei Huang, Wenzhai Cao, Junying Chen.  (2026)  Cyclodextrin metal-organic framework engineered titanium surface: Targeted modulation of foam cell lipid homeostasis and inflammatory resolution.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:41689943] [10.1016/j.colsurfb.2026.115550]

142. Li Xiang, Ling Ling, Chi Chaoxian, Ding Chuan-Fan.  (2026)  Rapid differentiation of D/L-homocysteine, D/L-homocystine, and S-allyl-D/L-cysteine using ion mobility-mass spectrometry.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,      [PMID:41692853] [10.1007/s00216-026-06378-5]

143. Peng Cui, Cailan Chen, Lilin Fang, Hanyu Zhang, Peiwen Wu, Kaihao Mo, Ge Niu, Yan Huang, Wenshuai Zhu, Zhichang Liu.  (2026)  Rapid fabrication of shaped cyclodextrin-based porous carbons for efficient PAHs capture.  MICROPOROUS AND MESOPOROUS MATERIALS,      [PMID:] [10.1016/j.micromeso.2026.114085]

144. Chan Li, Xue Yang, Yunfei Zou, Li Zhang, Chuhuan Wei, Yan Ran, E. Zhao, Jibiao Yuan, Keshan Wang, Yongguo Jin, Ying Zhou, Qiujin Zhu, Yuxin Cheng, Yuanyuan Liu.  (2026)  W/O/W emulsion-filled egg white gel co-stabilized by protein and γ-cyclodextrin MOFs with multi-chamber encapsulation potential.  FOOD RESEARCH INTERNATIONAL,      [PMID:] [10.1016/j.foodres.2026.118910]