Cytochalasin E - ≥99% , CAS No.36011-19-5

CAS: 36011-19-5 Cat. No.: C1423603 Peso molecular: 495.56 Beilstein Registry Number: 1096975 Número EC: 252-835-7 PubChem CID: 5458385

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Cytochalasin E, an epoxide containing Aspergillus -derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation.

Specifications

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99%

Nombres e identificadores

• Sonrisas canónicas: CC1CC=CC2C3C(O3)(C(C4C2(C(=O)NC4CC5=CC=CC=C5)OC(=O)OC=CC(C1=O)(C)O)C)C
• IUPAC Name: (1S,5E,7R,9S,11E,13S,14S,16R,17S,18S,19S)-19-benzyl-7-hydroxy-7,9,16,17-tetramethyl-2,4,15-trioxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-5,11-diene-3,8,21-trione
• InChIKey: LAJXCUNOQSHRJO-ZYGJITOWSA-N
• INCHI: 1S/C28H33NO7/c1-16-9-8-12-19-23-27(4,35-23)17(2)21-20(15-18-10-6-5-7-11-18)29-24(31)28(19,21)36-25(32)34-14-13-26(3,33)22(16)30/h5-8,10-14,16-17,19-21,23,33H,9,15H2,1-4H3,(H,29,31)/b12-8+,14-13+/t16-,17-,19-,20-,21-,23-,26+,27+,28+/m0/s1
• Isómeros SMILES: C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@]2(C(=O)N[C@H]4CC5=CC=CC=C5)OC(=O)O/C=C/[C@@](C1=O)(C)O)C)C
• WGK Alemania: 3
• RTECS: HA5360000
• PubChem CID: 5458385
• Peso molecular: 495.56
• Beilstein: 1096975

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Alkaloids and derivatives
    • Clase Cytochalasans

• Kingdom: Organic compounds
• Superclass: Alkaloids and derivatives
• Clase: Cytochalasans
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Cytochalasans
• Alternative Parents: Macrolactams Isoindolones Oxepanes Pyrrolidine-2-ones Acyloins Benzene and substituted derivatives Carbonic acid diesters Tertiary alcohols Enol esters Secondary carboxylic acid amides Cyclic ketones Lactams Oxacyclic compounds Azacyclic compounds Dialkyl ethers Epoxides Organic oxides Organopnictogen compounds Hydrocarbon derivatives Organonitrogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Cytoglobosin skeleton - Cytochalasan - Macrolactam - Isoindolone - Isoindoline - Isoindole or derivatives - Oxepane - Monocyclic benzene moiety - Carbonic acid diester - Benzenoid - Acyloin - 2-pyrrolidone - Pyrrolidone - Enol ester - Tertiary alcohol - Pyrrolidine - Carboxamide group - Cyclic ketone - Ketone - Lactam - Secondary carboxylic acid amide - Carbonic acid derivative - Carboxylic acid derivative - Organoheterocyclic compound - Azacycle - Ether - Oxirane - Oxacycle - Dialkyl ether - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Alcohol - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Carbonyl group - Organonitrogen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as cytochalasans. These are fungal metabolites structurally characterized by the presence of an isoindolone nucleus fused to a macrocyclic ring, which can either a lactone, as in cytochalasin B, a carbonate, as in cytochalasin E, or a carbocycle, as in cytochalasin D, H, and K.
• External Descriptors: cytochalasan alkaloid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y