D-4-Hydroxyphenylglycine - Moligand™, 10 mM in DMSO , CAS No.22818-40-2

CAS: 22818-40-2 Cat. No.: D1499044 Peso molecular: 167.16 Beilstein Registry Number: 2210998 Número EC: 245-247-7

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin and Cefadroxil.

Specifications

Especificaciones y pureza

Moligand™, 10 mM in DMSO

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nombres e identificadores

• Isómeros SMILES: C1=CC(=CC=C1[C@H](C(=O)O)N)O
• WGK Alemania: 3
• Peso molecular: 167.16
• Beilstein: 2210998
• Reaxy-Rn: 513130
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=513130&ln=

Propiedades químicas y físicas

• Rotación específica [α]: -158 ° (C=1, 1mol/L HCl)
• Punto de fusión (°C): 204°C

Referencias

1. Xin Pan, Anni Li, Zhiyi Peng, Xiaoqi Ji, Jianlin Chu, Bingfang He.  (2020)  Efficient synthesis of β-lactam antibiotics with in situ product removal by a newly isolated penicillin G acylase.  BIOORGANIC CHEMISTRY,      [PMID:32213361] [10.1016/j.bioorg.2020.103765]

2. Jiajie Ye, Anni Li, Tianshu Chu, Xin Pan, Bingfang He.  (2019)  Poly-lysine supported cross-linked enzyme aggregates of penicillin G acylase and its application in synthesis of β-lactam antibiotics.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:31381925] [10.1016/j.ijbiomac.2019.08.021]

3. Pan Xin, Wang Li, Ye Jiajie, Qin Song, He Bingfang.  (2018)  Efficient synthesis of β-lactam antibiotics with very low product hydrolysis by a mutant Providencia rettgeri penicillin G acylase.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,  102  (4): (1749-1758).  [PMID:29306966] [10.1007/s00253-017-8692-8]