D-Aspartic acid - Moligand™, ≥98% , Excitatory amino acid transporter 1;Excitatory amino acid transporter 2;Excitatory amino acid transporter 3;Excitatory amino acid transporter 4;Excitatory amino acid transporter 5;Agonist of GluN1;Agonist of GluN2A;Agon, Excitatory amino acid transporter 1;Excitatory amino acid transporter 2;Excitatory amino acid transporter 3;Excitatory amino acid transporter 4;Excitatory amino acid transporter 5;Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agon

CAS: 1783-96-6 Cat. No.: A105951 Peso molecular: 133.10 Beilstein Registry Number: 1723529 Número EC: 217-234-6
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
2,2'-methanediylbis(1H-benzimidazole) | 6-benzyloxy-1H-indole | C4H7NO4 | delta-aspartate | SR-01000597731 | C00402 | 7-Benzyloxy-1H-indole | BP-12717 | EN300-67412 | NCGC00024498-01 | Q27076990 | D-Aminosuccinic acid | MFCD0046411
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
25g
A105951-25g
4

13,90US$

20,90US$
Guardar 7,00 US$ (33.49%)
100g
A105951-100g
3

31,90US$

47,90US$
Guardar 16,00 US$ (33.40%)
250g
A105951-250g
1

37,90US$

56,90US$
Guardar 19,00 US$ (33.39%)
500g
A105951-500g
2

43,90US$

65,90US$
Guardar 22,00 US$ (33.38%)
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 24 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
2, 2'-methanediylbis(1H-benzimidazole) | 6-benzyloxy-1H-indole | C4H7NO4 | delta-aspartate | SR-01000597731 | C00402 | 7-Benzyloxy-1H-indole | BP-12717 | EN300-67412 | NCGC00024498-01 | Q27076990 | D-Aminosuccinic acid | MFCD0046411
Especificaciones y pureza
Moligand™, ≥98%
Mecanismos bioquímicos y fisiológicos
Endogenous NMDA receptor agonist with similar activity to the L-isomer. Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.L-isomeralso available.
Condiciones de almacenamiento de almacenamiento
Room temperature
Enviado en
Normal
Grado
Moligand™
Tipo de acción
AGONIST
Mecanismo de acción
Excitatory amino acid transporter 1;Excitatory amino acid transporter 2;Excitatory amino acid transporter 3;Excitatory amino acid transporter 4;Excitatory amino acid transporter 5;Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agon
Pureza
≥98%
Nombres e identificadores
Pubchem Sid488186215
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488186215
Sonrisas canónicasC(C(C(=O)O)N)C(=O)O
IUPAC Name(2R)-2-aminobutanedioic acid
InChIKeyCKLJMWTZIZZHCS-UWTATZPHSA-N
INCHI1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
Isómeros SMILES C([C@H](C(=O)O)N)C(=O)O
WGK Alemania 1
RTECS CI9097500
CAS alternativo 1783-96-6,27881-01-2
Términos de entrada MeSH 3-hydroxy-N-(2-methyl-1-oxo-2-propenyl)-;D Aspartate;D Aspartic Acid;D-Aspartate;D-Aspartic Acid
Peso molecular 133.10
Beilstein 1723529
Reaxy-Rn 774618
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=774618&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClaseCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentAspartic acid and derivatives
Alternative Parents D-alpha-amino acids  Fatty acids and conjugates  Dicarboxylic acids and derivatives  Amino acids  Carboxylic acids  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Aspartic acid or derivatives - Alpha-amino acid - D-alpha-amino acid - Dicarboxylic acid or derivatives - Fatty acid - Amino acid - Carboxylic acid - Organic oxide - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Amine - Organic nitrogen compound - Hydrocarbon derivative - Aliphatic acyclic compound
DescripciónThis compound belongs to the class of organic compounds known as aspartic acid and derivatives. These are compounds containing an aspartic acid or a derivative thereof resulting from reaction of aspartic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors Other amino acids
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
SLC1A1 Tchem Excitatory amino acid transporter 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC1A7 Tchem Excitatory amino acid transporter 5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC1A3 Tchem Excitatory amino acid transporter 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC1A6 Tchem Excitatory amino acid transporter 4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC1A2 Tchem Excitatory amino acid transporter 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN1 Tclin Glutamate receptor ionotropic, NMDA 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2A Tclin Glutamate receptor ionotropic, NMDA 2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2B Tclin Glutamate receptor ionotropic, NMDA 2B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2C Tclin Glutamate receptor ionotropic, NMDA 2C (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2D Tclin Glutamate receptor ionotropic, NMDA 2D (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM6 Tchem Metabotropic glutamate receptor 6 (361 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM1 Tchem Metabotropic glutamate receptor 1 (2309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC1A3 Tchem Excitatory amino acid transporter 1 (586 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Grm2 Metabotropic glutamate receptor 2 (1326 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor (6467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

23 results found

Lot NumberCertificate TypeFechaArticulo
H2119080Certificate of AnalysisJun 09, 2025 A105951
H2119197Certificate of AnalysisJun 09, 2025 A105951
D2607087Certificate of AnalysisMay 06, 2025 A105951
E2614098Certificate of AnalysisMay 06, 2025 A105951
G2528098Certificate of AnalysisMay 06, 2025 A105951
G2528100Certificate of AnalysisMay 06, 2025 A105951
H2504750Certificate of AnalysisMay 06, 2025 A105951
H2504749Certificate of AnalysisMay 06, 2025 A105951
H2504748Certificate of AnalysisMay 06, 2025 A105951
D2511035Certificate of AnalysisApr 17, 2025 A105951
D2409159Certificate of AnalysisMar 20, 2024 A105951
D2409160Certificate of AnalysisMar 20, 2024 A105951
K1918152Certificate of AnalysisSep 05, 2023 A105951
I2224077Certificate of AnalysisJul 04, 2022 A105951
K2329235Certificate of AnalysisJul 04, 2022 A105951
I2224078Certificate of AnalysisJul 04, 2022 A105951
I2224079Certificate of AnalysisJul 04, 2022 A105951
B2324077Certificate of AnalysisJul 04, 2022 A105951
I2224076Certificate of AnalysisJul 04, 2022 A105951
H2412489Certificate of AnalysisJul 04, 2022 A105951
H2308230Certificate of AnalysisJul 04, 2022 A105951
B2511010Certificate of AnalysisJul 04, 2022 A105951
D2511033Certificate of AnalysisAug 09, 2021 A105951

Show more ⌵

Propiedades químicas y físicas
SolubilidadSlightly soluble in water, Soluble in 1N ammonium hydroxide (100 mg/ml), and dilute HCl. Insoluble in ether, and alcohol.
Rotación específica [α]-24.0 to -26.0 deg(C=8, HCl(1+1))
Punto de fusión (°C)300°C
Peso molecular133.100 g/mol
XLogP3-2.800
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass133.038 Da
Monoisotopic Mass133.038 Da
Topological Polar Surface Area101.000 Ų
Heavy Atom Count9
Formal Charge0
Complexity133.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
Referencias
1. Wei Jia, Xin Wang.  (2023)  3-Chloropropane-1,2-diol exposure adversely influenced the bio-accessibility signatures of digested infant foods by suppressing the destabilization of α-lactalbumin and d-aspartate oxidase in a dose-dependent manner.  FOOD CHEMISTRY,      [PMID:37385056] [10.1016/j.foodchem.2023.136729]
2. Yonglei Han, Chao Zhou, Shuchen Weng, Guicheng Yu, Fang Lin, Hanlin Hu, Yongfei Wang, Haoran Lin.  (2022)  Natural Product Additive with Multifunctional Groups Enhancing the Efficiency and Stability of Perovskite Solar Cells.  Solar RRL,  (4): (2200998).  [PMID:] [10.1002/solr.202200998]
3. Haoyuan Li, Hongxiang Zhu, Zongyan Quan, Zhiping Chen, Lei Wang, Hui He.  (2022)  Tailoring of a bionic bifunctional cellulose nanocrystal-based gold nanocluster probe for the detection of intracellular pathological biomarkers.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:36309238] [10.1016/j.ijbiomac.2022.10.192]
4. Shuli Liu, Xiaoling Wu, Jun Xiong, Xin Yuan, Min-Hua Zong, Wen-Yong Lou.  (2022)  Aspartic acid based metal–organic frameworks with dual function of NADH peroxidase and glycerol dehydrogenase-mimicking activities.  Materials Chemistry Frontiers,  (22): (3391-3401).  [PMID:] [10.1039/D2QM00770C]
5. Arabi Maryam, Ostovan Abbas, Wang Yunqing, Mei Rongchao, Fu Longwen, Li Jinhua, Wang Xiaoyan, Chen Lingxin.  (2022)  Chiral molecular imprinting-based SERS detection strategy for absolute enantiomeric discrimination.  Nature Communications,  13  (1): (1-14).  [PMID:36180485] [10.1038/s41467-022-33448-w]
6. Shutong Yang, Liancheng Gu, Fangling Wu, Xinhua Dai, Fuxing Xu, Qiaoyu Li, Xiang Fang, Shaoning Yu, Chuan-Fan Ding.  (2022)  The chirality determination of amino acids by forming complexes with cyclodextrins and metal ions using ion mobility spectrometry, and a DFT calculation.  TALANTA,      [PMID:35272154] [10.1016/j.talanta.2022.123363]
7. Lamei Yang, Feng Luo, Weili Wei.  (2021)  Simultaneous determination of the concentration and enantiomeric excess of amino acids with a coumarin-derived achiral probe.  Analytical Methods,  13  (16): (1905-1910).  [PMID:33913945] [10.1039/D1AY00271F]
8. Wen Luo, Huaxiao Liu, Xuan Liu, Lixiao Liu, Wenbo Zhao.  (2021)  Biocompatibility nanoprobe of MXene N-Ti3C2 quantum dot/Fe3+ for detection and fluorescence imaging of glutathione in living cells.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:33639506] [10.1016/j.colsurfb.2021.111631]
9. Yang Dan, Mei Shiliang, Wen Zhuoqi, Wei Xian, Cui Zhongjie, Yang Bobo, Wei Chang, Qiu Yi, Li Min, Li Hui, Zhang Wanlu, Xie Fengxian, Wang Le, Guo Ruiqian.  (2020)  Dual-emission of silicon nanoparticles encapsulated lanthanide-based metal-organic frameworks for ratiometric fluorescence detection of bacterial spores.  MICROCHIMICA ACTA,  187  (12): (1-9).  [PMID:33206253] [10.1007/s00604-020-04643-7]
10. Yanyang Zhu, Minxin Cui, Jiajun Ma, Qijin Zhang.  (2019)  Fluorescence detection of d-aspartic acid based on thiol-ene cross-linked molecularly imprinted optical fiber probe.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2019.127323]
11. Yanni Miao, Qi Liu, Wei Wang, Li Liu, Li Wang.  (2017)  Enantioseparation of amino acids by micellar capillary electrophoresis using binary chiral selectors and determination of D-glutamic acid and D-aspartic acid in rice wine.  JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES,      [PMID:] [10.1080/10826076.2017.1364263]
12. Chao Ding, Hanjun Sun, Jinsong Ren, Xiaogang Qu.  (2016)  Immobilization of enzyme on chiral polyelectrolyte surface.  ANALYTICA CHIMICA ACTA,      [PMID:28010846] [10.1016/j.aca.2016.11.047]
13. Fangqin Wang, Wenrong Cai, Lilan Tan, Junyao Li, Datong Wu, Yong Kong.  (2024)  A Liquid–Liquid Interfacial Strategy for Construction of Electroactive Chiral Covalent–Organic Frameworks with the Aim to Enlarge the Testing Scope of Chiral Electroanalysis.  ANALYTICAL CHEMISTRY,      [PMID:38335728] [10.1021/acs.analchem.3c05744]
14. Siying Wu, Xuehua Zhang, Wenyan Tang, Yue Zhang, Xin Lv, Yu-Ting Zhuang.  (2024)  A ratiometric fluorescence platform based on bifunctional MOFs for sensitive detection of organophosphorus pesticides.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2024.106971]
15. Xinyi Wang, Zezhen Zhang, Weishan Deng, Haolan Xiao, Liming Xia, Lili Wu.  (2025)  Carbon nanotube incorporated polyphenol electro-responsive ultrafiltration membranes toward dye separation.  Journal of Water Process Engineering,      [PMID:] [10.1016/j.jwpe.2025.107379]
16. Hui Liu, Huiting Xu, Zhaofeng Song, Zhengwen Li, Saiwei Zhang, Yili Zhang, Jixiang Wang, Xiaoyong Qian.  (2025)  Effects of alkaline pretreatment on the distribution of amino acid enantiomers and their biofunctions during the anaerobic digestion of waste activated sludge.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.159334]
17. Xiaoran Shi, Hui Zhao, Han Zhang, Qunfang Li, Fangming Lou.  (2024)  Highly selective fluorescence detection of L-selenium-methylselenocysteine in selenium-enriched Cardamine violifolia.  Analytical Methods,  16  (26): (4373-4380).  [PMID:38895898] [10.1039/D4AY00320A]
18. Lilan Tan, Wenrong Cai, Fangqin Wang, Junyao Li, Datong Wu, Yong Kong.  (2024)  Postsynthetic Modification Strategy for Constructing Electrochemiluminescence-Active Chiral Covalent Organic Frameworks Performing Efficient Enantioselective Sensing.  ANALYTICAL CHEMISTRY,      [PMID:38394220] [10.1021/acs.analchem.3c05887]
19. Luzheng Dong, Jun Wu, Xiashi Zhu.  (2024)  Preparation of amino acid chiral ionic liquid and visual chiral recognition of glutamine and phenylalanine enantiomers.  CHIRALITY,  36  (4): (e23665).  [PMID:38570326] [10.1002/chir.23665]
20. Jinqiu Li, Fanghao Wang, Hao Zhang, Duxia Cao, Ruifang Guan.  (2025)  One-pot synthesis of fluorescent nanoprobes based on D-cys-based CDs and quantitative detection of lysine enantiomers.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:40267581] [10.1016/j.saa.2025.126143]
21. Jinhua Xu, Jinyu Zhang, Wenmin Zhang, Shiye Xie, Lan Zhang.  (2025)  Controllable synthesis of chiral hierarchical porous Co(OH)2 and its application in rapid chiral recognition and separation.  ANALYTICA CHIMICA ACTA,      [PMID:40480689] [10.1016/j.aca.2025.344212]
22. Ji Qi, Pibin Bing, Lanju Liang, Xin Yan, Haiyun Yao, Zhenhua Li, Ziqun Wang, Zhongyang Li, Qing Liu, Guifang Wu.  (2025)  A graphene oxide enhanced terahertz metamaterial for ultra-sensitive detection of D-aspartic acid solution.  Journal of Materials Chemistry C,      [PMID:] [10.1039/D5TC02590G]
23. Yifan Liu, Yiyu Yang, Minjie Peng, Wen Zang, Chaozhen Wang, Yuenan Zhang, Changyong Gao, Aiguo Wu, Yujie Zhang.  (2025)  Rapid colorimetric detection of the anticoagulant heparin based on an etching mechanism using I- responsive Cu-Au NPs.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.116349]
24. Simin Zhang, Xiangfeng Chen, Yaping Shi, Xiangyu Zhu, Zongwei Cai.  (2026)  Soft-Chain-Induced Ultrahigh-Resolution Chiral Separation of Amino Acids via Bimetallic Immobilization in MALDI-TIMS-MS.  ANALYTICAL CHEMISTRY,      [PMID:41701523] [10.1021/acs.analchem.5c07869]
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