D-erythro-sphingosine-1-phosphate (C20 base) - Moligand™, ≥99% , Agonist of S1P 2 receptor, CAS No.799812-75-2, Agonist of S1P 2 receptor

CAS: 799812-75-2 Cat. No.: D130702 Peso molecular: 407.52

GRADE & PURITY Moligand™, ≥99%

Synonyms

(2S,3R,4E)-2-Azaniumyl-3-hydroxyicos-4-en-1-yl hydrogen phosphate | GTPL11496 | [(E,2S,3R)-2-azaniumyl-3-hydroxyicos-4-enyl] hydrogen phosphate | Sphingosine-1-Phosphate (d20:1), D-erythro-sphingosine-1-phosphate (C20 base), powder | D-erythro-Sphingosine

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

product description：

Sphingosine-1-phosphate (S1P) is a zwitterionic sphingolipid. It is found in insects, yeasts and plants. Sphingosine-1-Phosphate (d20:1) is a phosphorylated derivative of long chain base C20 sphingosine.

application：

Sphingosine-1-phosphate (S1P)-d7 has been used as a reference standard in liquid chromatography/tandem mass spectrometry analysis for quantitative analyses of S1P d20:1 in central nervous system of healthy mice and in human glioblastoma tissue.

Biochemical mechanism:

Sphingosine-1-phosphate (S1P) is an important cellular metabolite and signaling lipid in animal cells. It aids in various physiological and cellular processes such as atherosclerosis, inflammation, immunity, tumorigenesis, and cell proliferation. S1P plays a vital role in mammalian brain and cardiac development. S1P d20:1 serves as a partial agonist at the S1P receptor 2 (S1P2). It has an ability to inhibit S1P d18:1‐mediated cyclooxygenase 2(COX2) induction.

Specifications

Sinónimos

(2S, 3R, 4E)-2-Azaniumyl-3-hydroxyicos-4-en-1-yl hydrogen phosphate | GTPL11496 | [(E, 2S, 3R)-2-azaniumyl-3-hydroxyicos-4-enyl] hydrogen phosphate | Sphingosine-1-Phosphate (d20:1), D-erythro-sphingosine-1-phosphate (C20 base), powder | D-erythro-Sphingosine

Especificaciones y pureza

Moligand™, ≥99%

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

AGONIST

Mecanismo de acción

Agonist of S1P 2 receptor

Pureza

≥99%

Nombres e identificadores

• Sonrisas canónicas: CCCCCCCCCCCCCCCC=CC(C(COP(=O)(O)[O-])[NH3+])O
• IUPAC Name: [(E,2S,3R)-2-azaniumyl-3-hydroxyicos-4-enyl] hydrogen phosphate
• InChIKey: YUUWWSOTAGQJFW-YIVRLKKSSA-N
• INCHI: 1S/C20H42NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)19(21)18-26-27(23,24)25/h16-17,19-20,22H,2-15,18,21H2,1H3,(H2,23,24,25)/b17-16+/t19-,20+/m0/s1
• Isómeros SMILES: CCCCCCCCCCCCCCC/C=C/[C@H]([C@H](COP(=O)(O)[O-])[NH3+])O
• Peso molecular: 407.52
• Reaxy-Rn: 35857216
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=35857216&ln=

Objetivos asociados (humanos)

S1PR2 Tchem Sphingosine 1-phosphate receptor 2 (0 Activities)

Discover Target: S1PR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)