D-Glucosamine sulphate - Moligand™,≥98% , CAS No.29031-19-4

CAS: 29031-19-4 Cat. No.: G117990 Peso molecular: 277.25 Número EC: 249-379-6

GRADE & PURITY Moligand™, ≥98%

Synonyms

D-Glucose, 2-amino-2-deoxy-, sulfate (salt) | EN300-7372813 | HY-N0487 | Glucosaminsulfat | (2R,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal sulfate | Glucosamine sulfate | CCG-267216 | Sulfuric acid--2-amino-2-deoxyhexose (1/1) | s3850 | Gevolox | AKOS0

Storage

Room temperature,Argon charged,Desiccated,Cool

Shipped In

Normal

Descripción general

Glucosamine sulfate is an antiarthritic agent isolated from chitin.

Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.

Specifications

Sinónimos

D-Glucose, 2-amino-2-deoxy-, sulfate (salt) | EN300-7372813 | HY-N0487 | Glucosaminsulfat | (2R, 3R, 4S, 5R)-2-Amino-3, 4, 5, 6-tetrahydroxyhexanal sulfate | Glucosamine sulfate | CCG-267216 | Sulfuric acid--2-amino-2-deoxyhexose (1/1) | s3850 | Gevolox | AKOS0

Especificaciones y pureza

Moligand™, ≥98%

Mecanismos bioquímicos y fisiológicos

Postranslational modification regulator. Inhibits N-glycosylation of certain proteins. Regulates TGF-β signaling. Downregulates HIF-1. Suppresses 5-HT-induced nociceptive responses. Shows analgesic effects in vivo. Orally active.

Condiciones de almacenamiento de almacenamiento

Room temperature, Argon charged, Desiccated, Cool

Enviado en

Normal

Grado

Moligand™

Tipo de acción

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 488187521
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488187521
• Sonrisas canónicas: C(C(C(C(C(C=O)N)O)O)O)O.OS(=O)(=O)O
• IUPAC Name: (2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal;sulfuric acid
• InChIKey: FGNPLIQZJCYWLE-BTVCFUMJSA-N
• INCHI: 1S/C6H13NO5.H2O4S/c7-3(1-8)5(11)6(12)4(10)2-9;1-5(2,3)4/h1,3-6,9-12H,2,7H2;(H2,1,2,3,4)/t3-,4+,5+,6+;/m0./s1
• Isómeros SMILES: C([C@H]([C@H]([C@@H]([C@H](C=O)N)O)O)O)O.OS(=O)(=O)O
• CAS alternativo: 14307-02-9；14999-43-0
• Peso molecular: 277.25

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Monosaccharides
          • Level6 Hexoses

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Monosaccharides
• Direct Parent: Hexoses
• Alternative Parents: Aminosaccharides Organic sulfuric acids Beta-hydroxy aldehydes 1,3-aminoalcohols Secondary alcohols Polyols Primary alcohols Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Hexose monosaccharide - Amino saccharide - Sulfuric acid - Beta-hydroxy aldehyde - Organic sulfuric acid or derivatives - 1,3-aminoalcohol - Secondary alcohol - Polyol - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Primary alcohol - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Aldehyde - Alcohol - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in water (slightly), alcohol, and chloroform.
• Sensibilidad: Moisture sensitive
• Peso molecular: 277.250 g/mol
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 5
• Exact Mass: 277.047 Da
• Monoisotopic Mass: 277.047 Da
• Topological Polar Surface Area: 207.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 223.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Fangjie Lu, Qinqin Wang, Mingyuan Zhu, Bin Dai.  (2023)  Deactivation and Regeneration of Nitrogen Doped Carbon Catalyst for Acetylene Hydrochlorination.  MOLECULES,  28  (3): (956).  [PMID:36770621] [10.3390/molecules28030956]

2. Hua Tian, Kaixin Zhu, Yang Jiang, Lin Wang, Wang Li, Zhifeng Yu, Cunqi Wu.  (2021)  Heterogeneous assembly of Ni–Co layered double hydroxide/sulfonated graphene nanosheet composites as battery-type materials for hybrid supercapacitors.  Nanoscale Advances,  3  (10): (2924-2933).  [PMID:36134181] [10.1039/D1NA00001B]

3. Wei Chen, Chi Wang, Yuying Gao, Yang Wu, Guomin Wu, Xiaowen Shi, Yumin Du, Hongbing Deng.  (2019)  Incorporating chitin derived glucosamine sulfate into nanofibers via coaxial electrospinning for cartilage regeneration.  CARBOHYDRATE POLYMERS,      [PMID:31826435] [10.1016/j.carbpol.2019.115544]

4. Shuai Ma, Li Zhang, Yang Wu, Wei Huang, Fangtian Liu, Mingguang Li, Yifeng Fan, Haibin Xia, Xianguo Wang, Xinzhi Li, Hongbing Deng.  (2024)  Glucosamine sulfate-loaded nanofiber reinforced carboxymethyl chitosan sponge for articular cartilage restoration.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:39116561] [10.1016/j.jcis.2024.07.207]

5. Chen Li, Yalu Xin, Wei Gao, Yongping Chen.  (2025)  Enabling a Robust Long-Life Zinc-Iodine Flow Battery by Stabilizing the Zinc Anode in a Halide-Rich Electrolyte.  Small,      [PMID:40872987] [10.1002/smll.202508359]

6. Shujie Wang, Hetao Zhang, Zhongping Shao, Li Liu.  (2025)  Engineering microporous humins derived from glucosamine for CO2 adsorption.  BIOMASS & BIOENERGY,      [PMID:] [10.1016/j.biombioe.2025.108346]

7. Jiaojiao Yan, Haoxin Cai, Shuai Ma, Xin Wen, Ze Zhao, Shixin Wang, Yiming Qi, Jun Wu, Hongbing Deng.  (2026)  Hierarchically reinforced injectable chitosan-based hydrogels integrating mechanical-bioactive nanofibers and chondrogenic cues for articular cartilage reconstruction.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41506501] [10.1016/j.ijbiomac.2026.150133]