D-Glucose 6-phosphate sodium salt - ≥97% , CAS No.54010-71-8

CAS: 54010-71-8 Cat. No.: G111871 Peso molecular: 282.12 Beilstein Registry Number: 5787568 Número EC: 258-921-0 PubChem CID: 23677332

GRADE & PURITY ≥97%

Synonyms

D-GLUCOSE-6-PHOSPHATE MONOSODIUM SALT | Sodium (2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl hydrogenphosphate | Robison ester monosodium salt | Sodium 6-O-(hydroxyphosphinato)hexose | D-Glucose 6-phosphate sodium salt

Storage

Store at 2-8°C

Shipped In

Wet ice

Descripción general

It is a reagent and enzyme substrate for G6PD (glucose-6-phosphate dehydrogenase). It is an inhibitor of HXK.
A reagent and enzyme substrate for glucose-6-phosphate dehydrogenase

Specifications

Sinónimos

D-GLUCOSE-6-PHOSPHATE MONOSODIUM SALT | Sodium (2R, 3R, 4S, 5R)-2, 3, 4, 5-tetrahydroxy-6-oxohexyl hydrogenphosphate | Robison ester monosodium salt | Sodium 6-O-(hydroxyphosphinato)hexose | D-Glucose 6-phosphate sodium salt

Especificaciones y pureza

≥97%

Mecanismos bioquímicos y fisiológicos

In cells, D-Glucose 6-phosphate sodium (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥97%

Nombres e identificadores

• Pubchem Sid: 488200495
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488200495
• Sonrisas canónicas: C(C(C(C(C(C=O)O)O)O)O)OP(=O)(O)[O-].[Na+]
• IUPAC Name: sodium;[(2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl] hydrogen phosphate
• InChIKey: OBHLNVXMRZXIII-BTVCFUMJSA-M
• INCHI: 1S/C6H13O9P.Na/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14;/h1,3-6,8-11H,2H2,(H2,12,13,14);/q;+1/p-1/t3-,4+,5+,6+;/m0./s1
• Isómeros SMILES: C([C@H]([C@H]([C@@H]([C@H](C=O)O)O)O)O)OP(=O)(O)[O-].[Na+]
• WGK Alemania: 3
• PubChem CID: 23677332
• Peso molecular: 282.12
• Beilstein: 5787568

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Monosaccharides
          • Level6 Monosaccharide phosphates

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Monosaccharides
• Direct Parent: Monosaccharide phosphates
• Alternative Parents: Hexoses Beta-hydroxy aldehydes Alkyl phosphates Alpha-hydroxyaldehydes Secondary alcohols 1,2-diols Organic sodium salts Organic oxides Hydrocarbon derivatives Organic cations
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Hexose monosaccharide - Monosaccharide phosphate - Beta-hydroxy aldehyde - Organic phosphoric acid derivative - Alkyl phosphate - Phosphoric acid ester - Alpha-hydroxyaldehyde - 1,2-diol - Secondary alcohol - Organic alkali metal salt - Polyol - Organic oxide - Alcohol - Organic salt - Organic sodium salt - Carbonyl group - Hydrocarbon derivative - Aldehyde - Organic cation - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in water (5 mg/ml), and aqueous buffers (1 mg/ml).
• Sensibilidad: Moisture sensitive； Moisture-proof
• Punto de fusión (°C): 204°C
• Peso molecular: 282.120 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 7
• Exact Mass: 282.012 Da
• Monoisotopic Mass: 282.012 Da
• Topological Polar Surface Area: 168.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 274.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Jianyong Li, Xiaojun Kong, Xiwang Li, Yajun Yang, Jiyu Zhang.  (2013)  Genotoxic evaluation of aspirin eugenol ester using the Ames test and the mouse bone marrow micronucleus assay.  FOOD AND CHEMICAL TOXICOLOGY,      [PMID:24140966] [10.1016/j.fct.2013.10.010]

2. Yunkai Sun, Xiaoxia Wu, Pei Zuo, Zhao Liu, Xuepei Miao, Jian Liu, Hairuo Wen.  (2024)  Synthesis and mutagenic risk of avanafil's potential genotoxic impurities.  RSC Advances,  14  (30): (21432-21438).  [PMID:38979469] [10.1039/D4RA02345E]