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(R)-2-Hydroxypentanedioic acid - Moligand™, ≥98% , CAS No.13095-47-1

CAS: 13095-47-1 Cat. No.: D697699 Peso molecular: 148.11 PubChem CID: 439391
COA
D-α-Hydroxyglutaric acid - Moligand™,≥98% CAS No(13095-47-1) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
(R)-2-Hydroxyglutaric acid | (R)-alpha-Hydroxyglutaric acid | D-2-Hydroxyglutaric acid | D-alpha-Hydroxyglutaric acid | 2-hydroxypentanedioic acid | (2R)-2-Hydroxypentanedioic acid | (2R)-hydroxyglutaric acid
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
25mg
D697699-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
148,90US$
50mg
D697699-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
214,90US$
100mg
D697699-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
343,90US$
250mg
D697699-250mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
582,90US$
Enter a quantity for the sizes you want to add.
Bulk / Custom
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Descripción general Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

D-α-Hydroxyglutaric acid ((R)-2-Hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling.

Specifications

Sinónimos
(R)-2-Hydroxyglutaric acid | (R)-alpha-Hydroxyglutaric acid | D-2-Hydroxyglutaric acid | D-alpha-Hydroxyglutaric acid | 2-hydroxypentanedioic acid | (2R)-2-Hydroxypentanedioic acid | (2R)-hydroxyglutaric acid
Especificaciones y pureza
Moligand™, ≥98%
Condiciones de almacenamiento de almacenamiento
Store at -20°C, Argon charged
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
ACTIVATOR
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasC(CC(=O)O)C(C(=O)O)O
IUPAC Name(2R)-2-hydroxypentanedioic acid
InChIKeyHWXBTNAVRSUOJR-GSVOUGTGSA-N
INCHI1S/C5H8O5/c6-3(5(9)10)1-2-4(7)8/h3,6H,1-2H2,(H,7,8)(H,9,10)/t3-/m1/s1
Isómeros SMILES C(CC(=O)O)[C@H](C(=O)O)O
PubChem CID 439391
Peso molecular 148.11

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClaseHydroxy acids and derivatives
SubclassShort-chain hydroxy acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentShort-chain hydroxy acids and derivatives
Alternative Parents Monosaccharides  Fatty acids and conjugates  Dicarboxylic acids and derivatives  Alpha hydroxy acids and derivatives  Secondary alcohols  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Short-chain hydroxy acid - Fatty acid - Monosaccharide - Dicarboxylic acid or derivatives - Alpha-hydroxy acid - Secondary alcohol - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
DescripciónThis compound belongs to the class of organic compounds known as short-chain hydroxy acids and derivatives. These are hydroxy acids with an alkyl chain the contains less than 6 carbon atoms.
External Descriptors 2-hydroxyglutaric acid
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGLN1 Tclin Egl nine homolog 1 (1702 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HIF1AN Tbio Hypoxia-inducible factor 1-alpha inhibitor (79 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4C Tchem Lysine-specific demethylase 4C (1129 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM2A Tchem Lysine-specific demethylase 2A (198 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTO Tchem Alpha-ketoglutarate-dependent dioxygenase FTO (473 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALKBH3 Tchem Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM5B Tchem Lysine-specific demethylase 5B (814 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TET2 Tchem Methylcytosine dioxygenase TET2 (57 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TET1 Tbio Methylcytosine dioxygenase TET1 (33 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
A085R Prolyl 4-hydroxylase (72 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeFechaArticulo
E2621377Certificate of AnalysisMay 08, 2026 D697699
E2621379Certificate of AnalysisMay 08, 2026 D697699
Propiedades químicas y físicas
Peso molecular148.110 g/mol
XLogP3-1.000
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass148.037 Da
Monoisotopic Mass148.037 Da
Topological Polar Surface Area94.800 Ų
Heavy Atom Count10
Formal Charge0
Complexity141.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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