D-Leucine - Moligand™, 10 mM in Water , CAS No.328-38-1

CAS: 328-38-1 Cat. No.: D1500998 Peso molecular: 131.17 Beilstein Registry Number: 1721721 Número EC: 206-327-7

GRADE & PURITY Moligand™, 10 mM in Water

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

D-Leucine is a more potent anti-seizure agent than L-leucine. D-leucine potently terminates seizures even after the onset of seizure activity. D-leucine, but not L-leucine, reduces long-term potentiation but had no effect on basal synaptic transmission in vitro.

Specifications

Especificaciones y pureza

Moligand™, 10 mM in Water

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nombres e identificadores

• Isómeros SMILES: CC(C)C[C@H](C(=O)O)N
• WGK Alemania: 3
• RTECS: OH2840000
• Peso molecular: 131.17
• Beilstein: 1721721
• Reaxy-Rn: 636005
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=636005&ln=

Propiedades químicas y físicas

• Rotación específica [α]: -15 ° (C=4, 6mol/L HCl)
• Punto de fusión (°C): 300°C

Referencias

1. Jingzhi Yang, Yami Ran, Shaopeng Liu, Chenhao Ren, Yuntian Lou, Pengfei Ju, Guoliang Li, Xiaogang Li, Dawei Zhang.  (2023)  Synergistic D-Amino Acids Based Antimicrobial Cocktails Formulated via High-Throughput Screening and Machine Learning.  Advanced Science,  11  (9): (2307173).  [PMID:38126652] [10.1002/advs.202307173]

2. Zhiyang Xu, Yinzhou Yan, Xingyuan Wang, Xiaolei Wang, Zhixiang Zhou, Xi Yang, Tianrui Zhai.  (2023)  Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point.  Advanced Science,      [PMID:38072636] [10.1002/advs.202308362]

3. Weijie Fu, Kai Zhang, Xiaohua Zhang, Guorong Fan, Zongde Wang, Shangxing Chen, Yangping Wen, Peng Wang.  (2022)  Synthesis of transition metal sulfide functionalized hierarchically porous carbons and their application as colorimetric-electrochemical dual-mode nanozyme sensing platform for dopamine.  ELECTROCHIMICA ACTA,      [PMID:] [10.1016/j.electacta.2022.141535]

4. Shutong Yang, Liancheng Gu, Fangling Wu, Xinhua Dai, Fuxing Xu, Qiaoyu Li, Xiang Fang, Shaoning Yu, Chuan-Fan Ding.  (2022)  The chirality determination of amino acids by forming complexes with cyclodextrins and metal ions using ion mobility spectrometry, and a DFT calculation.  TALANTA,      [PMID:35272154] [10.1016/j.talanta.2022.123363]

5. Kai Zhang, Zhonghui Zhuo, Guorong Fan, Zongde Wang, Shangxing Chen, Lulu Xu, Yangping Wen, Peng Wang.  (2021)  Nano-ZnS decorated hierarchically porous carbon electrocatalyst with multiple enzyme-like activities as a nanozyme sensing platform for simultaneous detection of dopamine, uric acid, guanine, and adenine.  Nanoscale,  13  (47): (20078-20090).  [PMID:34846060] [10.1039/D1NR06017A]

6. Lamei Yang, Feng Luo, Weili Wei.  (2021)  Simultaneous determination of the concentration and enantiomeric excess of amino acids with a coumarin-derived achiral probe.  Analytical Methods,  13  (16): (1905-1910).  [PMID:33913945] [10.1039/D1AY00271F]

7. Xuan Kuang, Yu Ma, Hao Su, Jine Zhang, Yu-Bin Dong, Bo Tang.  (2014)  High-Performance Liquid Chromatographic Enantioseparation of Racemic Drugs Based on Homochiral Metal–Organic Framework.  ANALYTICAL CHEMISTRY,      [PMID:24380495] [10.1021/ac403674p]

8. Qian Du, Xiaoyu Zhao, Xiping Mei, Yaqin Zhao, Chuan Dong, Junfen Li.  (2024)  A sensitive sensor based on carbon dots for the determination of Fe3+ and ascorbic acid in foods.  Analytical Methods,  16  (6): (939-949).  [PMID:38259231] [10.1039/D3AY02133E]

9. Hui Liu, Huiting Xu, Zhaofeng Song, Zhengwen Li, Saiwei Zhang, Yili Zhang, Jixiang Wang, Xiaoyong Qian.  (2025)  Effects of alkaline pretreatment on the distribution of amino acid enantiomers and their biofunctions during the anaerobic digestion of waste activated sludge.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.159334]

10. Chong Liu, Xiaoxue Han, Qing Zhang, Zhuojia Shi, Yuqing Zhang, Yu Chen.  (2024)  Green low-melting mixture solvents/ionic liquids-based carbon materials and lithium-ion batteries recycling leachate unexpectedly cause water pollution from dissolved organic matter.  JOURNAL OF THE INDIAN CHEMICAL SOCIETY,      [PMID:] [10.1016/j.jics.2024.101458]

11. Lilan Tan, Wenrong Cai, Fangqin Wang, Junyao Li, Datong Wu, Yong Kong.  (2024)  Postsynthetic Modification Strategy for Constructing Electrochemiluminescence-Active Chiral Covalent Organic Frameworks Performing Efficient Enantioselective Sensing.  ANALYTICAL CHEMISTRY,      [PMID:38394220] [10.1021/acs.analchem.3c05887]

12. Luzheng Dong, Jun Wu, Xiashi Zhu.  (2024)  Preparation of amino acid chiral ionic liquid and visual chiral recognition of glutamine and phenylalanine enantiomers.  CHIRALITY,  36  (4): (e23665).  [PMID:38570326] [10.1002/chir.23665]

13. Chen Qi, Wenke Yang, Fuyan He, Jinshui Yao.  (2020)  The Thermal Properties and Degradability of Chiral Polyester-Imides Based on Several l/d-Amino Acids.  Polymers,  12  (9): (2053).  [PMID:32916788] [10.3390/polym12092053]

14. Mengmeng Ji, Jinwei Li, Liuping Fan, Liang Wang, Shengquan Huang.  (2026)  Combined Effects of Quercetagetin and D-Amino Acids against Pseudomonas aeruginosa: Anti-Quorum Sensing, Antibacterial, and Antibiofilm activities.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2026.108393]

15. Qi Yi, Yi-Qi Sheng, Dong-Qi Han, Xue-Wei Lin, Chi-Kit Siu, Zhong-Ping Yao.  (2026)  Chiral recognition of amino acids by mass spectrometry with the combinations of two different chiral selectors.  Cell Reports Physical Science,      [PMID:] [10.1016/j.xcrp.2026.103144]

16. Simin Zhang, Xiangfeng Chen, Yaping Shi, Xiangyu Zhu, Zongwei Cai.  (2026)  Soft-Chain-Induced Ultrahigh-Resolution Chiral Separation of Amino Acids via Bimetallic Immobilization in MALDI-TIMS-MS.  ANALYTICAL CHEMISTRY,      [PMID:41701523] [10.1021/acs.analchem.5c07869]