Endotoxin Free, ≥99% Endotoxin Free for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 30 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Tested and Certified for in vivo imaging.
Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.
Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).
Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.
| Sonrisas canónicas | C1C(N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)[O-].[K+] |
|---|---|
| IUPAC Name | potassium;(4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylate |
| InChIKey | UMBKGTQQGYPQBE-OGFXRTJISA-M |
| INCHI | 1S/C11H8N2O3S2.K/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;/h1-3,7,14H,4H2,(H,15,16);/q;+1/p-1/t7-;/m1./s1 |
| WGK Alemania | 3 |
| Peso molecular | 318.41 |
| Beilstein | 5416262 |
| Reaxy-Rn | 41031268 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=41031268&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| 1. Haiyang Wang, Yixuan Hou, Taian Lin, Ihsan Ullah, Qing Xu, Ye Liu, Taosha Jin, Yangning Zhang, Youyong Yuan. (2025) Sono-Responsive Hydrogel for Fractionated PROTAC Release to Alleviate Resistance and Immunosuppression Induced by Multi-Course Postoperative Radiotherapy. ADVANCED FUNCTIONAL MATERIALS, [PMID:] [10.1002/adfm.202512954] |
| 2. Lifeng Liu, Junmei Zhang, Shihao Wang, Zhirong He, Xiaohu Wang, Limin Tian, Mingxi Li, Guangyu Long, Siqi Zhu, Zhengyu Jiang, Suxin Li. (2025) Reprogramming Macrophage via an Antigen Phagocytosis-Presentation Nanoenhancer for Improved Cancer Immunotherapy. ACS Nano, [PMID:40835579] [10.1021/acsnano.5c09460] |
| 3. Ji Chen, Xiya Guo, Yanqiao Ma, Jie Zhou, Ping Li, Mingxin Dong, Jie Du. (2025) Selective Activation of Conditionally Replicating Influenza A Virus in Pulmonary Tumors for Enhanced Oncolytic Efficacy and Systemic Safety. Advanced Healthcare Materials, [PMID:40879091] [10.1002/adhm.202502017] |
| 4. Shuo Tang, Lujun Wang, Wenjie Lu, Lingzhen Ding, Xia Liu, Yu Tao, Mingchao Xu, Wenyou Fang, Shengqi Chen, Rongfeng Hu. (2025) Screening Ganoderma Lucidum Spore Oil-based Oral Solid Self-microemulsion of Paclitaxel for Enhanced Chemotherapeutic Efficacy via Immunomodulation in Colorectal Cancer. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.jddst.2025.107419] |
| 5. Yunyan Li, Tong Yan, Wenya Chang, Chongjiang Cao, Dawei Deng. (2019) Fabricating an intelligent cell-like nano-prodrug via hierarchical self-assembly based on the DNA skeleton for suppressing lung metastasis of breast cancer. Biomaterials Science, 7 (9): (3652-3661). [PMID:31169833] [10.1039/C9BM00630C] |
| 6. Xinzi Hu, Guangzhi Li, Chenfan Kong, Lisha Liu, Dashi Deng, Guizhong Xin, Jian Pan, Song Wu, Qifang Lei. (2024) Fluorinated chitosan mediated transepithelial delivery of sanguinarine-loaded platinum (IV) prodrug for intravesical instillation therapy of muscle-invasive bladder cancer. JOURNAL OF CONTROLLED RELEASE, [PMID:39701454] [10.1016/j.jconrel.2024.12.023] |
| 7. Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng-Ming (Spring) Kong, Gen Yang. (2025) Fragment Autoantigens Stimulated T-Cell-Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine. Advanced Science, [PMID:40135850] [10.1002/advs.202502937] |
| 8. Ximu Li, Mengyao Ma, Ni An, Xiaoxuan Yao, Guzailinuer Yasen, Mingyuan Zhong, Zheng Jin, Zhonggui He, Yongjun Wang, Hongzhuo Liu. (2025) Lipid-Rapamycin Nanovaccines Overcome the Antidrug Antibody Barrier in Biologic Therapies. ACS Nano, [PMID:39847793] [10.1021/acsnano.4c11928] |
| 9. Wei Cheng, Zhiran Duan, Han Chen, Yanjun Wang, Chao Wang, Yuqing Pan, Jie Wu, Ning Wang, Haijing Qu, Xiangdong Xue. (2025) Macrophage membrane-camouflaged pure-drug nanomedicine for synergistic chemo- and interstitial photodynamic therapy against glioblastoma. Acta Biomaterialia, [PMID:39800099] [10.1016/j.actbio.2025.01.016] |
| 10. Chenxu Zhu, Chuang Li, Yibo Du, Shi Chen, Xingliang Liu, Lixin Liu, Yongming Chen. (2025) Precise Oligopeptides Block CCDC25 Interaction with DNA in Neutrophil Extracellular Traps Inhibiting Tumor Metastasis. ACS Applied Materials & Interfaces, [PMID:40000243] [10.1021/acsami.5c00670] |
| 11. Yixuan Wang, Songyu Yang, Shengbin Chen, Yingbing Zuo, Xiaoyu Mu, Hongmei Zhou, Yufei Yao, Xiaoping Peng, Wenjuan Li. (2025) UPLC-Q-TOF/MS-based serum metabolomics revealed anti-tumor mechanism of ethanol-soluble acidic components from Camellia oleifera cake and synergy with PD-1 inhibitor. Food Bioscience, [PMID:] [10.1016/j.fbio.2025.106005] |
| 12. Qianqian Wang, Xin Yuan, Cuijuan Liu, Ying Huang, Lin Li, Yimin Zhu. (2025) Peptide-based CAR-NK cells: A novel strategy for the treatment of solid tumors. BIOCHEMICAL PHARMACOLOGY, [PMID:39761877] [10.1016/j.bcp.2025.116741] |
| 13. Lei Huang, Xinbo Li, Hongyan Zhang, Feng Liu, Zheng Dai, Fang Xiao, Lin Wang, Zheng Wang. (2025) Zinc Ion-Coordinated Sericin Calcium Phosphate Nanovaccines Induce Hyperactive Dendritic Cells and Synergistic Activation of T Cells for Cancer Immunotherapy. ACS Nano, [PMID:40177975] [10.1021/acsnano.4c17491] |
| 14. Yiping Liang, Xinyi Cao, Zhiwen Ma, Chengge Ma, Haitong Wen, Meng Li, Hangyi Wu, Ting Liu, Xiaoyu Lu, Huixia Lv. (2025) Enterohepatic circulation-inspired nano-platform for less-hepatotoxicity hepatocellular carcinoma therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:40354905] [10.1016/j.ijpharm.2025.125693] |
| 15. Haihong Yang, Zhan Gao, Yizi Zhou, Xueer Ge, Xiaorong Pan, Jiakun Li, Zhihui Zhang, Xuanli Jin, Guotao Liu, Zepeng He, Hong Liu, Zhijia Liu, Lixin Liu, Yongming Chen. (2025) Tertiary amine N-oxide zwitterionic lipids facilitate muscle-selective mRNA vaccine delivery for enhancing cDC1-mediated antitumor efficacy. JOURNAL OF CONTROLLED RELEASE, [PMID:40436347] [10.1016/j.jconrel.2025.113892] |
| 16. Huilan He, Yun Zheng, Jinlong Ji, Chunlian Ye, Yu Sun, Yuwei Peng, Ying Zhang, Zhiyuan Zhong. (2025) Liposomal all-trans retinoic acid boosts anti-tumor immunity of radiotherapy via mitigating cancer stemness and remedying tumor microenvironment. JOURNAL OF CONTROLLED RELEASE, [PMID:40602432] [10.1016/j.jconrel.2025.113995] |
| 17. Song Ruilian, Wang Yixiang, Li Yanjun, Wang Qifei, Zhang Siyu, Sun Dongfa, Sun Genlou, Sun Longqing, Ren Xifeng. (2025) Unraveling the regulatory network of barley grain metabolism through the integrative analysis of multiomics and mQTL. Nature Communications, 16 (1): (1-20). [PMID:40593515] [10.1038/s41467-025-60501-1] |
| 18. Wei Liu, Meihui Zhang, Huiyuan Lv, Chuanxu Yang. (2025) Formulation-Driven Optimization of PEG-Lipid Content in Lipid Nanoparticles for Enhanced mRNA Delivery In Vitro and In Vivo. Pharmaceutics, 17 (8): (950). [PMID:40870973] [10.3390/pharmaceutics17080950] |
| 19. Ciliang Guo, Tian Gao, Bin Xue, Louqian Zhang, Shuo Wang, Rongrong Xiao, Lingkai Kong, Yuxin Zhang, Qilei Xin, Yi Cao, Xiaosong Gu, Chunping Jiang, Junhua Wu. (2025) In situ extended immune activation instantly after tumor resection by oncolytic virus controls postoperative tumor recurrence. Cell Reports Medicine, [PMID:41045932] [10.1016/j.xcrm.2025.102399] |
| 20. Qing Liang, Yue Peng, Linyao Zhao, Zhenlin Yang, Xiaowei Chen, Jinfei Li, Zhiyuan Wu, Kun Chen, Bolun Zhou, Yang Liu, Bin Hu, Chunfeng Qu, Moyan Zhang, Shugeng Gao. (2025) Pulmonary macrophage-targeted RNAi and mRNA co-delivery via SORT lipid nanoparticles enhances immunotherapy in lung cancer. JOURNAL OF CONTROLLED RELEASE, [PMID:41371503] [10.1016/j.jconrel.2025.114519] |
| 21. Wang Jia, Wang Zhiji, Li Kaiming, Liu Yue, Tang Chunming, Gao Huimin, Zhou Yupeng, Wang Pengpeng, Wu Haisi, Liu Pengfei, Xu Huae, Li Xiaolin. (2025) Tumor targeting dendritic nanocarrier with immunogenic cell death inducing and TIGIT blockade for synergistic chemo-immunotherapy against TNBC. JOURNAL OF NANOBIOTECHNOLOGY, 23 (1): (759). [PMID:41354959] [10.1186/s12951-025-03875-0] |
| 22. Gan Ziqi, Huang Jing, Duan Shuting, Lin Minzhao, Deng Shaohui, Huang Sicong, Wang Jiachen, Shuai Xintao, Xiao Zecong. (2025) αPD-1-conjugated acid-cleavable nanodrugs overcomes cellular immunotherapy barriers in pancreatic tumors. Nature Communications, [PMID:41398151] [10.1038/s41467-025-67254-x] |
| 23. Liao Fangli, Tong Yanran, Sun Hua, Chen Sen, Wen Siyang, Du Yan-e, Jiang Linshan, Huang Tong, Liu Manran, Chen Weixian, Yang Liping. (2026) Nerves Stimulates Crosstalk between Gastric Cancer and Group 3 Innate Lymphoid Cells to Enhance Immunosuppression. CANCER RESEARCH, [PMID:41534088] [10.1158/0008-5472.CAN-25-3092] |
| 24. Li Li, Weijia Huang, Zhenyang Zhao, Yuan Gao, Rui Zhang, Zhonghao Liao, Yuxin Hu, Qing Ma, Yang Yang, Yongjun Wang, Hongzhuo Liu. (2026) Cholesterolated Rapamycin Prodrug Liposomes Induce Antigen-Specific Tolerance and Enable AAV Redosing. MOLECULAR PHARMACEUTICS, [PMID:41674289] [10.1021/acs.molpharmaceut.5c01748] |
| 25. Fangzhou Yang, Yunqian Lu, Xiaoxue Lang, Lina Sun, Hang Zou, Ziting Zhou, Yaoyao Guo, Yifei Guo, Xiangtao Wang, Meihua Han. (2026) Homologous Tumor Cell-Derived Delivery of Doxorubicin via Liquid Nitrogen-Treated 4T1 Cells for Targeted Breast Cancer Therapy. MOLECULAR PHARMACEUTICS, [PMID:41711552] [10.1021/acs.molpharmaceut.5c01664] |
| 26. Kiet Le Anh Cao, Oktaviardi Bityasmawan Abdillah, Tomoyuki Hirano, Eka Lutfi Septiani, Takashi Ogi. (2026) Sustainable Porous Carbon Derived from Lignin for High‐Performance CO2 Capture. Chemistry-An Asian Journal, 21 (4): (e00988). [PMID:41730805] [10.1002/asia.202500988] |
| 27. Xuanzhi Luo, Yuan Zeng, Xue Wang, Mujin Li, Ya-Lei Wang, Tiantian Peng, Cuiyan Ma, Qian Hua. (2026) 18ï ¢-Glycyrrhetinic acid suppresses glioblastoma by regulating p38 signaling pathway: an integrative approach combining network analysis, transcriptomics, and experimental assessment. Frontiers in Pharmacology, [PMID:41782932] [10.3389/fphar.2026.1727072] |
| 28. Lizhou Lin, Xiao Li, Wenyun Guo, Jirong Xie, Xiaolong Li, Xin Guan, Chongke Zhao, HaoHao Yin, Huixiong Xu. (2026) LIFUS-driven engineered bacteria reprogram immunosuppressive niches via mechano-NOTCH signaling. Cell Reports Medicine, [PMID:41806839] [10.1016/j.xcrm.2026.102658] |
| 29. Zhang Zhe, Xiao Bing, Jiang Yupeng, Niu Lixia, Wang Li, Cai Juan. (2026) UBC9-mediated SUMOylation of CORO1C drives lung adenocarcinoma progression via Arp2/3-dependent cytoskeletal remodeling. Cell Death & Disease, [PMID:] [10.1038/s41419-026-08653-w] |
| 30. Meichang Feng, Weiwei Liu, Xiumin Chen, Linghan Huang, Xuan Peng, Yue Li, Shiwu Gao, Zhaoli Lin, Liping Xu, Jinlong Guo. (2026) A hierarchical ScMYB11L–ScZAT1–ScDREB1A module defines a derepression pathway for cold-response regulation in sugarcane. Plant Stress, [PMID:] [10.1016/j.stress.2026.101340] |
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