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Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 44 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Dansyl Chloride, also known as 5-dimethylamino naphthalene-1-sulfonyl chloride, is a pre-column derivatization reagent. After the derivatization reaction, the fluorescent derivatives are analyzed using several analytical methods like NMR, IR, UV-vis, and fluorescence microscopy. Dansyl Chloride is a typical aromatic sulphonyl chloride that reacts with various bases, resulting in derivatives with variable stability.
| Sonrisas canónicas | CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)Cl |
|---|---|
| IUPAC Name | 5-(dimethylamino)naphthalene-1-sulfonyl chloride |
| InChIKey | XPDXVDYUQZHFPV-UHFFFAOYSA-N |
| INCHI | 1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3 |
| Isómeros SMILES | CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)Cl |
| RTECS | QK3688000 |
| Peso molecular | 269.74 |
| Reaxy-Rn | 2217205 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2217205&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Naphthalenes |
| Subclass | Naphthalene sulfonic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 1-naphthalene sulfonic acids and derivatives |
| Alternative Parents | Dialkylarylamines Sulfonyls Sulfonyl chlorides Organosulfonic acids and derivatives Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homopolycyclic compounds |
| Substituents | 1-naphthalene sulfonic acid or derivatives - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl chloride - Sulfonyl halide - Sulfonyl - Tertiary amine - Organic nitrogen compound - Amine - Organosulfur compound - Organonitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organic oxide - Aromatic homopolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as 1-naphthalene sulfonic acids and derivatives. These are organic aromatic compounds that contain a naphthalene moiety that carries a sulfonic acid group (or a derivative thereof) at the 1-position. Naphthalene is a bicyclic compound that is made up of two fused benzene ring. |
| External Descriptors | aminonaphthalene |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Jun 10, 2026 | D133513 | |
| Certificate of Analysis | Dec 10, 2025 | D133513 | |
| Certificate of Analysis | Dec 09, 2025 | D133513 | |
| Certificate of Analysis | Dec 09, 2025 | D133513 | |
| Certificate of Analysis | Dec 09, 2025 | D133513 | |
| Certificate of Analysis | Dec 09, 2025 | D133513 | |
| Certificate of Analysis | Dec 09, 2025 | D133513 | |
| Certificate of Analysis | Dec 09, 2025 | D133513 | |
| Certificate of Analysis | Oct 13, 2025 | D133513 | |
| Certificate of Analysis | Sep 28, 2025 | D133513 | |
| Certificate of Analysis | Sep 28, 2025 | D133513 | |
| Certificate of Analysis | Sep 28, 2025 | D133513 | |
| Certificate of Analysis | Sep 28, 2025 | D133513 | |
| Certificate of Analysis | Sep 16, 2025 | D133513 | |
| Certificate of Analysis | Sep 16, 2025 | D133513 | |
| Certificate of Analysis | Apr 09, 2025 | D133513 | |
| Certificate of Analysis | Apr 02, 2025 | D133513 | |
| Certificate of Analysis | Mar 11, 2025 | D133513 | |
| Certificate of Analysis | Mar 11, 2025 | D133513 | |
| Certificate of Analysis | Mar 11, 2025 | D133513 | |
| Certificate of Analysis | Mar 11, 2025 | D133513 | |
| Certificate of Analysis | Mar 11, 2025 | D133513 | |
| Certificate of Analysis | Mar 11, 2025 | D133513 | |
| Certificate of Analysis | Mar 11, 2025 | D133513 | |
| Certificate of Analysis | Dec 12, 2024 | D133513 | |
| Certificate of Analysis | Dec 12, 2024 | D133513 | |
| Certificate of Analysis | Dec 12, 2024 | D133513 | |
| Certificate of Analysis | Dec 12, 2024 | D133513 | |
| Certificate of Analysis | Dec 12, 2024 | D133513 | |
| Certificate of Analysis | Nov 08, 2024 | D133513 | |
| Certificate of Analysis | Nov 08, 2024 | D133513 | |
| Certificate of Analysis | Nov 08, 2024 | D133513 | |
| Certificate of Analysis | Nov 08, 2024 | D133513 | |
| Certificate of Analysis | Nov 08, 2024 | D133513 | |
| Certificate of Analysis | Jun 16, 2023 | D133513 | |
| Certificate of Analysis | Jun 16, 2023 | D133513 | |
| Certificate of Analysis | Jun 16, 2023 | D133513 | |
| Certificate of Analysis | Jun 16, 2023 | D133513 | |
| Certificate of Analysis | Jun 16, 2023 | D133513 | |
| Certificate of Analysis | Feb 27, 2023 | D133513 | |
| Certificate of Analysis | Feb 27, 2023 | D133513 | |
| Certificate of Analysis | Feb 27, 2023 | D133513 | |
| Certificate of Analysis | Feb 27, 2023 | D133513 | |
| Certificate of Analysis | Nov 25, 2022 | D133513 | |
| Certificate of Analysis | Nov 25, 2022 | D133513 | |
| Certificate of Analysis | Nov 25, 2022 | D133513 | |
| Certificate of Analysis | Nov 25, 2022 | D133513 | |
| Certificate of Analysis | Nov 25, 2022 | D133513 | |
| Certificate of Analysis | Oct 26, 2022 | D133513 |
| Solubilidad | Soluble in DMF, acetone (50 mg/ml), chloroform, pyridine, benzene, and dioxane. Insoluble in water;Insoluble in water,Soluble in acetone、 chloroform、benzene |
|---|---|
| Sensibilidad | Sensitive to humidity, light, and heat |
| Rotación específica [α] | 1.64 |
| Punto de ebullición (°C) | 371.30 °C at 760 mmHg |
| Punto de fusión (°C) | 69-73°C |
| Peso molecular | 269.750 g/mol |
| XLogP3 | 3.500 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 269.028 Da |
| Monoisotopic Mass | 269.028 Da |
| Topological Polar Surface Area | 45.800 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 363.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Shijin Xiong, Xiaoyan Xu, Qiaozhen Liu, Yazhou Xu, Hongbing Ren, Tao Xiong, Mingyong Xie. (2023) Integrated metatranscriptomics and metabolomics revealed the metabolic pathways of biogenic amines during Laotan Suancai fermentation. Food Bioscience, [PMID:] [10.1016/j.fbio.2023.103517] |
| 2. Chen Chen, Yingfang Zhang, Ximo Wang, Xuguang Qiao, Geoffrey I.N. Waterhouse, Zhixiang Xu. (2023) A core-satellite self-assembled SERS aptasensor containing a “biological-silent region” Raman tag for the accurate and ultrasensitive detection of histamine. Food Science and Human Wellness, [PMID:] [10.26599/FSHW.2022.9250089] |
| 3. Wenjing Liu, Xiaoxiang Hu, Linghao Fang, Yujie Cai. (2023) Insights into the Unusual Activity of a Novel Homospermidine Synthase with a Promising Application to Produce Spermidine. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:37622688] [10.1021/acs.jafc.3c03037] |
| 4. Furong Jin, Xinyue Yin, Yang Wan, Jiukai Zhang, Jindi Wang, Xiangbo Fu, Tianxin Fu, Buwei Liu, Yongshi Chen, Bo Tian, Zhibiao Feng. (2023) Ultrasonic–microwave synergistic supramolecular solvent liquid–liquid microextraction of trace biogenic amines in fish and beer based on solidification of floating organic droplet. FOOD CHEMISTRY, [PMID:37516607] [10.1016/j.foodchem.2023.136965] |
| 5. Jianghua Chen, Yuanshuai Zang, Mengyi Chen, Chen Shi, Manlei Zhang, Bin Di, Cheng Jiang. (2023) Sensitive determination of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in wastewater by solid-phase extraction with pre-column derivatization and liquid chromatography-tandem mass spectrometry. Analytical Methods, 15 (21): (2693-2699). [PMID:37226492] [10.1039/D3AY00420A] |
| 6. Shan Xu, Peifang Chen, Xichi Lin, Imran Mahmood Khan, Xiaoyuan Ma, Zhouping Wang. (2022) Controllable synthesis of flower-like AuNFs@ZIF-67 core-shell nanocomposites for ultrasensitive SERS detection of histamine in fish. ANALYTICA CHIMICA ACTA, [PMID:36641156] [10.1016/j.aca.2022.340776] |
| 7. Jian-Jun Zhong, Liping Xia, Liuru Xue, Boyu Liu, Lingling Zhao, Hua Ye, Zhanming Li. (2022) Analytical method for histamine, urocanic acid isomers, and their precursor histidine in fish sauce based on precolumn dansylation and high-performance liquid chromatography. FOOD CONTROL, [PMID:] [10.1016/j.foodcont.2022.109566] |
| 8. Yixuan Fan, Runze Yu, Yongfeng Chen, Yufeng Sun, Geoffrey I. N. Waterhouse, Zhixiang Xu. (2022) A Capillary Electrophoresis Method Based on Molecularly Imprinted Solid-Phase Extraction for Selective and Sensitive Detection of Histamine in Foods. MOLECULES, 27 (20): (6987). [PMID:36296580] [10.3390/molecules27206987] |
| 9. Xirui Chen, Yujie Tu, Song Cheng, Xujing Guo, Tianying Lu, Yuqian Guo, Xiaolin Huang, Yonghua Xiong, Ben Zhong Tang. (2022) A colorimetric and ratiometric fluorescent paper chip for biogenic amine monitoring based on a simple pH-sensitive AIEgen. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2022.137928] |
| 10. Xujing Guo, Xirui Chen, Rui Chen, Yujie Tu, Tianying Lu, Yuqian Guo, Liang Guo, Yonghua Xiong, Xiaolin Huang, Ben Zhong Tang. (2022) Ratiometric Monitoring of Biogenic Amines by a Simple Ammonia-Response Aiegen. Foods, 11 (7): (932). [PMID:35407018] [10.3390/foods11070932] |
| 11. Xu Xu, Jiaxin Gao, Di Cao, Xiang Li, Xin Zhao, Shuang Yue, Lei Zhang. (2022) Designed 3D N-doped magnetic porous carbon spheres for sensitive monitoring of biogenic amine by simultaneous microwave-assisted derivatization and magnetic-solid phase extraction. JOURNAL OF CHROMATOGRAPHY A, [PMID:35149412] [10.1016/j.chroma.2022.462882] |
| 12. Yanfang Niu, Sen Li, Junning Zhang, Wang Wan, Zhenzhu He, Jun Liu, Keliang Liu, Sainan Ren, Liqin Ge, Xin Du, Zhongze Gu. (2021) Static–Dynamic Fluorescence Patterns Based on Photodynamic Disulfide Reactions for Versatile Information Storage. Small, 17 (35): (2102224). [PMID:34310021] [10.1002/smll.202102224] |
| 13. Junmei Fan, Enrui Wu, Jinlong Dong, Ruitao Zhu, Meiqin Li, Jiangning Gao, Hongfei Han, Liping Ding. (2021) A minimalist ratiometric fluorescent sensor based on non-covalent ternary platform for sensing H2S in aqueous solution and serum. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2021.126299] |
| 14. Yi-Fang Li, Zheng-Zhong Lin, Cheng-Yi Hong, Zhi-Yong Huang. (2020) Histamine detection in fish samples based on indirect competitive ELISA method using iron-cobalt co-doped carbon dots labeled histamine antibody. FOOD CHEMISTRY, [PMID:33601655] [10.1016/j.foodchem.2020.128812] |
| 15. Guohui Li, Dixuan Huang, Li Wang, Yu Deng. (2020) Highly efficient whole-cell biosynthesis of putrescine by recombinant Escherichia coli. BIOCHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.bej.2020.107859] |
| 16. Xuefei Shao, Baocai Xu, Hui Zhou, Conggui Chen, Peijun Li. (2020) Insight into the mechanism of decreasing N-nitrosodimethylamine by Lactobacillus pentosus R3 in a model system. FOOD CONTROL, [PMID:] [10.1016/j.foodcont.2020.107534] |
| 17. Chong Ma, Shijuan Zhang, Xia Wu, Jinmao You. (2020) Permanently Positively Charged Stable Isotope Labeling Agents and Its Application in the Accurate Quantitation of Alkylphenols Migrated from Plastics to Edible Oils. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:32697581] [10.1021/acs.jafc.0c03413] |
| 18. Peng Wang, Sihan Wang, Li Chen, Wenting Wang, Baohui Wang, Yunwen Liao. (2020) A novel peptide-based fluorescent probe for sensitive detection of zinc (II) and its applicability in live cell imaging. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:32526399] [10.1016/j.saa.2020.118549] |
| 19. Mengting Ni, Xing Hu, Deming Gong, Guowen Zhang. (2020) Inhibitory mechanism of vitexin on α-glucosidase and its synergy with acarbose. FOOD HYDROCOLLOIDS, [PMID:] [10.1016/j.foodhyd.2020.105824] |
| 20. Yuxuan Liu, Yunxin Zheng, Hao Wu, Wei Zhang, Tianyu Ren, Shengping You, Wei Qi, Rongxin Su, Zhimin He. (2020) Development of an integrated process for the production of high-purity cadaverine from lysine decarboxylase. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 95 (5): (1542-1549). [PMID:] [10.1002/jctb.6348] |
| 21. Hao Qian, Xiaofei Shen, Hailong Huang, Yan Zhang, Mingtao Zhang, Huiqing Wang, Zhongkai Wang. (2019) Helical poly(phenyl isocyanide)s grafted selectively on C-6 of cellulose for improved chiral recognition ability. CARBOHYDRATE POLYMERS, [PMID:31888853] [10.1016/j.carbpol.2019.115737] |
| 22. Xu Mao, Jian Wang, Qian Wang, Lan Yang, Yilin Li, Hao Lin, Ying Peng, Jiang Zheng. (2019) Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism. DRUG METABOLISM AND DISPOSITION, 47 (8): (919-927). [PMID:31147316] [10.1124/dmd.119.086892] |
| 23. Ni Zeng, Guowen Zhang, Xing Hu, Junhui Pan, Deming Gong. (2019) Mechanism of fisetin suppressing superoxide anion and xanthine oxidase activity. Journal of Functional Foods, [PMID:] [10.1016/j.jff.2019.04.044] |
| 24. Yu Zong, Jia Chen, Jinxuan Hou, Wenwen Deng, Xiaoyan Liao, Yuxiu Xiao. (2018) Hexafluoroisopropanol-alkyl carboxylic acid high-density supramolecular solvent based dispersive liquid-liquid microextraction of steroid sex hormones in human urine. JOURNAL OF CHROMATOGRAPHY A, [PMID:30391035] [10.1016/j.chroma.2018.10.041] |
| 25. Huafang Ding, Xiaqing Wu, Junhui Pan, Xing Hu, Deming Gong, Guowen Zhang. (2018) New Insights into the Inhibition Mechanism of Betulinic Acid on α-Glucosidase. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:29902001] [10.1021/acs.jafc.8b02992] |
| 26. Yujing Zhou, Jue Xu, Xiankang Fan, Qiang Xia, Changyu Zhou, Yangyang Hu, Hongbing Yan, Yangying Sun, Daodong Pan. (2025) Effect of pulsed electric field pretreatment synergistic mixed bacterial agent fermentation on the flavor and quality of air-dried goose meat and its molecular mechanism. POULTRY SCIENCE, [PMID:40014970] [10.1016/j.psj.2025.104926] |
| 27. Yumeng Sui, Jiasheng Lu, Ying-ao Zhu, Baohua Kong, Hui Wang, Ligang Qin, Qian Chen. (2024) Effects of exogenous autoinducer-2 precursor on the ability of Lactiplantibacillus plantarum SH7 to degrade biogenic amines: In vitro and in a dry-sausage model. Food Bioscience, [PMID:] [10.1016/j.fbio.2024.104263] |
| 28. Niuniu Bai, Jianlin He, Bihong Hong, Zelong Wu, Liping Wang, Zongze Shao. (2025) Fast Preparation of Fish Sauce Treated With Marine Protease-Producing Bacillus zhangzhouensis sp.. JOURNAL OF FOOD PROCESSING AND PRESERVATION, 2025 (1): (6298724). [PMID:] [10.1155/jfpp/6298724] |
| 29. Xiaoyu Xie, Xiuqiong Zhang, Tiantian Chen, Di Yu, Ming Ma, Xin Lu, Guowang Xu. (2024) High-coverage identification of hydroxyl compounds based on pyridine derivatization-assisted liquid chromatography mass spectrometry. ANALYTICA CHIMICA ACTA, [PMID:39182991] [10.1016/j.aca.2024.343065] |
| 30. Yujing Zhou, Jue Xu, Xiankang Fan, Zihang Shi, Wei Wang, Ming Huang, Kaiyong Yao, Hongbing Yan, Changyu Zhou, Yangyang Hu, Daodong Pan. (2025) Pulsed electric field assisted mixed bacteria to efficiently control biogenic amines in air-dried goose. Food Bioscience, [PMID:] [10.1016/j.fbio.2025.105935] |
| 31. Wenjing Liu, Xiaoxiang Hu, Yi Yan, Yujie Cai. (2024) Rational engineering of homospermidine synthase for enhanced catalytic efficiency toward spermidine synthesis. Synthetic and Systems Biotechnology, [PMID:38699566] [10.1016/j.synbio.2024.04.012] |
| 32. Lichen Gou, Ling Li, Siqi Wei, Yunfei Tian, Xiandeng Hou, Li Wu. (2024) Sensitive detection of histamine utilizing the SERS platform combined with an azo coupling reaction and a composite hydrophobic layer. TALANTA, [PMID:39002262] [10.1016/j.talanta.2024.126531] |
| 33. Xiao Zhang, Sihao Li, Heng Liu, Anurak Wongta, Zhenlin Xu, Kai Zhou, Surat Hongsibsong. (2025) Isolation and Characterizations of Histamine- and Tyramine-Producing Strains Isolated from Fermented Soybean Food: Soy Sauce and Soybean Paste. Foods, 14 (14): (2407). [PMID:40724227] [10.3390/foods14142407] |
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| 38. Ma Yanfei, Zhong Yifan, Tang Wenjie, Valencak Teresa G., Liu Jingliang, Deng Zhaoxi, Mao Jiangdi, Liu Daren, Wang Shanshan, Wang Yuhao, Wang Haifeng. (2025) Lactobacillus reuteri ZJ617 attenuates metabolic syndrome via microbiota-derived spermidine. Nature Communications, 16 (1): (1-15). [PMID:39837844] [10.1038/s41467-025-56105-4] |
| 39. Shan Zhao, Qiyan Huang, Yiran Wang, Yujing Wang, Wenyu Wang, BenxuYang, Aiguo Feng, Chao Li, Shufen Wu, Changlu Wang. (2025) Study on the inhibitory effect and mechanism of Monascus yellow pigments (ankaflavin and monascinon) on porcine pancreatic lipase. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2025.128884] |
| 40. Jiana Lin, Ying Chen, Gongke Li, Yuling Hu. (2025) Supramolecular calix[6]arene-COF with pocket-like cavities for host-guest recognition-based SERS detection of tryptamine and seafood freshness monitoring. FOOD CHEMISTRY, [PMID:41386090] [10.1016/j.foodchem.2025.147438] |
| 41. Meng Zhang, Yanxiao Jiang, Qiong Wu, Hong Zhang, Kai Yu, Guangfeng Kan, Daqian Song, Jie Jiang. (2025) Online Electroextraction–NanoESI–MS for Rapid Analysis of Catecholamines in Urine. ANALYTICAL CHEMISTRY, [PMID:41405594] [10.1021/acs.analchem.5c05250] |
| 42. Fan Zhihao, Shen Yu, Usman Muhammad, Su Kerui, Shahid Ayesha, Zhao Anqi, Li Xinyu, Zhang Beixiao, Xu Jingliang. (2026) Stabilizing Bioactive Components in Fresh Spirulina via Hydroxypropyl-β-Cyclodextrin-Loaded Curcumin: A Functional Preservation Approach. Food and Bioprocess Technology, 19 (3): (155). [PMID:] [10.1007/s11947-026-04255-8] |
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| 44. Bairong Fu, Dongqin Tan, Jing Jin, Lei Tong, Longxing Wang, Yihou Peng, Ningbo Geng, Lidong Wu, Huilian Ma, Yuwen Ni, Jiping Chen. (2026) Fragmentation Pathways and Enhanced Detection Sensitivity of OH-PBDEs via LC-ESI-MS2: A Comprehensive Analytical Investigation. ANALYTICAL CHEMISTRY, [PMID:] [10.1021/acs.analchem.5c06791] |
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