Dansyl Chloride(DNSCl) - Moligand™, ≥98%(HPLC) , CAS No.605-65-2

CAS: 605-65-2 Cat. No.: D133513 Peso molecular: 269.74 Número EC: 210-092-6
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
Synonyms
1-Chlorosulfonyl-5-dimethylaminonaphthalene | CHEBI:51907 | DNS chloride | DNSClDNSCl | AM10162 | QMU9166TJ4 | Q409512 | 5-dimethylaminonaphthalenesulfonyl chloride | 1-NAPHTHALENESULFONYL CHLORIDE, 5-(DIMETHYLAMINO)- | 5-Dimethylaminonaphthyl-5-sulfonyl
Storage
Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
250mg
D133513-250mg
5

11,90US$

17,90US$
Guardar 6,00 US$ (33.52%)
1g
D133513-1g
3

19,90US$

29,90US$
Guardar 10,00 US$ (33.44%)
5g
D133513-5g
3

31,90US$

47,90US$
Guardar 16,00 US$ (33.40%)
10g
D133513-10g
2

44,90US$

67,90US$
Guardar 23,00 US$ (33.87%)
25g
D133513-25g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

93,90US$

140,90US$
Guardar 47,00 US$ (33.36%)
100g
D133513-100g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

300,90US$

451,90US$
Guardar 151,00 US$ (33.41%)
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Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 44 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Dansyl Chloride, also known as 5-dimethylamino naphthalene-1-sulfonyl chloride, is a pre-column derivatization reagent. After the derivatization reaction, the fluorescent derivatives are analyzed using several analytical methods like NMR, IR, UV-vis, and fluorescence microscopy. Dansyl Chloride is a typical aromatic sulphonyl chloride that reacts with various bases, resulting in derivatives with variable stability.

Specifications

Sinónimos
1-Chlorosulfonyl-5-dimethylaminonaphthalene | CHEBI:51907 | DNS chloride | DNSClDNSCl | AM10162 | QMU9166TJ4 | Q409512 | 5-dimethylaminonaphthalenesulfonyl chloride | 1-NAPHTHALENESULFONYL CHLORIDE, 5-(DIMETHYLAMINO)- | 5-Dimethylaminonaphthyl-5-sulfonyl
Especificaciones y pureza
Moligand™, ≥98%(HPLC)
Mecanismos bioquímicos y fisiológicos
Fluorogenic primary amine reactive reagent for N -terminal derivatization of amino acids and peptides, and for polyamine detection by reverse phase HPLC and other analytical procedures.
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Protected from light, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Pureza
≥98%(HPLC)
Nombres e identificadores
Sonrisas canónicasCN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)Cl
IUPAC Name5-(dimethylamino)naphthalene-1-sulfonyl chloride
InChIKeyXPDXVDYUQZHFPV-UHFFFAOYSA-N
INCHI1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
Isómeros SMILES CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)Cl
RTECS QK3688000
Peso molecular 269.74
Reaxy-Rn 2217205
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2217205&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseNaphthalenes
SubclassNaphthalene sulfonic acids and derivatives
Intermediate Tree Nodes Not available
Direct Parent1-naphthalene sulfonic acids and derivatives
Alternative Parents Dialkylarylamines  Sulfonyls  Sulfonyl chlorides  Organosulfonic acids and derivatives  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homopolycyclic compounds
Substituents 1-naphthalene sulfonic acid or derivatives - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl chloride - Sulfonyl halide - Sulfonyl - Tertiary amine - Organic nitrogen compound - Amine - Organosulfur compound - Organonitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organic oxide - Aromatic homopolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as 1-naphthalene sulfonic acids and derivatives. These are organic aromatic compounds that contain a naphthalene moiety that carries a sulfonic acid group (or a derivative thereof) at the 1-position. Naphthalene is a bicyclic compound that is made up of two fused benzene ring.
External Descriptors aminonaphthalene
Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

49 results found

Lot NumberCertificate TypeFechaArticulo
I2403016Certificate of AnalysisJun 10, 2026 D133513
B2419170Certificate of AnalysisDec 10, 2025 D133513
L2525365Certificate of AnalysisDec 09, 2025 D133513
L2525364Certificate of AnalysisDec 09, 2025 D133513
L2525363Certificate of AnalysisDec 09, 2025 D133513
L2525362Certificate of AnalysisDec 09, 2025 D133513
L2525361Certificate of AnalysisDec 09, 2025 D133513
L2525360Certificate of AnalysisDec 09, 2025 D133513
A2402152Certificate of AnalysisOct 13, 2025 D133513
I2523316Certificate of AnalysisSep 28, 2025 D133513
I2523315Certificate of AnalysisSep 28, 2025 D133513
I2523314Certificate of AnalysisSep 28, 2025 D133513
I2523313Certificate of AnalysisSep 28, 2025 D133513
I2503408Certificate of AnalysisSep 16, 2025 D133513
I2503406Certificate of AnalysisSep 16, 2025 D133513
G2303265Certificate of AnalysisApr 09, 2025 D133513
C2315274Certificate of AnalysisApr 02, 2025 D133513
C2526335Certificate of AnalysisMar 11, 2025 D133513
C2526336Certificate of AnalysisMar 11, 2025 D133513
C2526337Certificate of AnalysisMar 11, 2025 D133513
C2526338Certificate of AnalysisMar 11, 2025 D133513
C2526339Certificate of AnalysisMar 11, 2025 D133513
D2503001Certificate of AnalysisMar 11, 2025 D133513
L2512107Certificate of AnalysisMar 11, 2025 D133513
B2507233Certificate of AnalysisDec 12, 2024 D133513
B2507229Certificate of AnalysisDec 12, 2024 D133513
B2507231Certificate of AnalysisDec 12, 2024 D133513
B2507230Certificate of AnalysisDec 12, 2024 D133513
B2507228Certificate of AnalysisDec 12, 2024 D133513
K2422684Certificate of AnalysisNov 08, 2024 D133513
K2422676Certificate of AnalysisNov 08, 2024 D133513
K2422677Certificate of AnalysisNov 08, 2024 D133513
K2422678Certificate of AnalysisNov 08, 2024 D133513
K2422685Certificate of AnalysisNov 08, 2024 D133513
G2303286Certificate of AnalysisJun 16, 2023 D133513
G2303279Certificate of AnalysisJun 16, 2023 D133513
G2303278Certificate of AnalysisJun 16, 2023 D133513
G2303269Certificate of AnalysisJun 16, 2023 D133513
G2303263Certificate of AnalysisJun 16, 2023 D133513
C2315273Certificate of AnalysisFeb 27, 2023 D133513
C2315277Certificate of AnalysisFeb 27, 2023 D133513
C2315275Certificate of AnalysisFeb 27, 2023 D133513
C2315276Certificate of AnalysisFeb 27, 2023 D133513
A2303148Certificate of AnalysisNov 25, 2022 D133513
A2303202Certificate of AnalysisNov 25, 2022 D133513
A2303199Certificate of AnalysisNov 25, 2022 D133513
A2303193Certificate of AnalysisNov 25, 2022 D133513
A2303190Certificate of AnalysisNov 25, 2022 D133513
J2220026Certificate of AnalysisOct 26, 2022 D133513

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Propiedades químicas y físicas
SolubilidadSoluble in DMF, acetone (50 mg/ml), chloroform, pyridine, benzene, and dioxane. Insoluble in water;Insoluble in water,Soluble in acetone、 chloroform、benzene
SensibilidadSensitive to humidity, light, and heat
Rotación específica [α]1.64
Punto de ebullición (°C)371.30 °C at 760 mmHg
Punto de fusión (°C)69-73°C
Peso molecular269.750 g/mol
XLogP33.500
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass269.028 Da
Monoisotopic Mass269.028 Da
Topological Polar Surface Area45.800 Ų
Heavy Atom Count17
Formal Charge0
Complexity363.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Shijin Xiong, Xiaoyan Xu, Qiaozhen Liu, Yazhou Xu, Hongbing Ren, Tao Xiong, Mingyong Xie.  (2023)  Integrated metatranscriptomics and metabolomics revealed the metabolic pathways of biogenic amines during Laotan Suancai fermentation.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2023.103517]
2. Chen Chen, Yingfang Zhang, Ximo Wang, Xuguang Qiao, Geoffrey I.N. Waterhouse, Zhixiang Xu.  (2023)  A core-satellite self-assembled SERS aptasensor containing a “biological-silent region” Raman tag for the accurate and ultrasensitive detection of histamine.  Food Science and Human Wellness,      [PMID:] [10.26599/FSHW.2022.9250089]
3. Wenjing Liu, Xiaoxiang Hu, Linghao Fang, Yujie Cai.  (2023)  Insights into the Unusual Activity of a Novel Homospermidine Synthase with a Promising Application to Produce Spermidine.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:37622688] [10.1021/acs.jafc.3c03037]
4. Furong Jin, Xinyue Yin, Yang Wan, Jiukai Zhang, Jindi Wang, Xiangbo Fu, Tianxin Fu, Buwei Liu, Yongshi Chen, Bo Tian, Zhibiao Feng.  (2023)  Ultrasonic–microwave synergistic supramolecular solvent liquid–liquid microextraction of trace biogenic amines in fish and beer based on solidification of floating organic droplet.  FOOD CHEMISTRY,      [PMID:37516607] [10.1016/j.foodchem.2023.136965]
5. Jianghua Chen, Yuanshuai Zang, Mengyi Chen, Chen Shi, Manlei Zhang, Bin Di, Cheng Jiang.  (2023)  Sensitive determination of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in wastewater by solid-phase extraction with pre-column derivatization and liquid chromatography-tandem mass spectrometry.  Analytical Methods,  15  (21): (2693-2699).  [PMID:37226492] [10.1039/D3AY00420A]
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11. Xu Xu, Jiaxin Gao, Di Cao, Xiang Li, Xin Zhao, Shuang Yue, Lei Zhang.  (2022)  Designed 3D N-doped magnetic porous carbon spheres for sensitive monitoring of biogenic amine by simultaneous microwave-assisted derivatization and magnetic-solid phase extraction.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:35149412] [10.1016/j.chroma.2022.462882]
12. Yanfang Niu, Sen Li, Junning Zhang, Wang Wan, Zhenzhu He, Jun Liu, Keliang Liu, Sainan Ren, Liqin Ge, Xin Du, Zhongze Gu.  (2021)  Static–Dynamic Fluorescence Patterns Based on Photodynamic Disulfide Reactions for Versatile Information Storage.  Small,  17  (35): (2102224).  [PMID:34310021] [10.1002/smll.202102224]
13. Junmei Fan, Enrui Wu, Jinlong Dong, Ruitao Zhu, Meiqin Li, Jiangning Gao, Hongfei Han, Liping Ding.  (2021)  A minimalist ratiometric fluorescent sensor based on non-covalent ternary platform for sensing H2S in aqueous solution and serum.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2021.126299]
14. Yi-Fang Li, Zheng-Zhong Lin, Cheng-Yi Hong, Zhi-Yong Huang.  (2020)  Histamine detection in fish samples based on indirect competitive ELISA method using iron-cobalt co-doped carbon dots labeled histamine antibody.  FOOD CHEMISTRY,      [PMID:33601655] [10.1016/j.foodchem.2020.128812]
15. Guohui Li, Dixuan Huang, Li Wang, Yu Deng.  (2020)  Highly efficient whole-cell biosynthesis of putrescine by recombinant Escherichia coli.  BIOCHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.bej.2020.107859]
16. Xuefei Shao, Baocai Xu, Hui Zhou, Conggui Chen, Peijun Li.  (2020)  Insight into the mechanism of decreasing N-nitrosodimethylamine by Lactobacillus pentosus R3 in a model system.  FOOD CONTROL,      [PMID:] [10.1016/j.foodcont.2020.107534]
17. Chong Ma, Shijuan Zhang, Xia Wu, Jinmao You.  (2020)  Permanently Positively Charged Stable Isotope Labeling Agents and Its Application in the Accurate Quantitation of Alkylphenols Migrated from Plastics to Edible Oils.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:32697581] [10.1021/acs.jafc.0c03413]
18. Peng Wang, Sihan Wang, Li Chen, Wenting Wang, Baohui Wang, Yunwen Liao.  (2020)  A novel peptide-based fluorescent probe for sensitive detection of zinc (II) and its applicability in live cell imaging.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:32526399] [10.1016/j.saa.2020.118549]
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36. Song Xue, Siru Ren, Li Wang, Qi Zhang.  (2019)  Evaluation of tetraalkylammonium amino acid ionic liquids as chiral ligands in ligand-exchange capillary electrophoresis.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:31597604] [10.1016/j.chroma.2019.460579]
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39. Shan Zhao, Qiyan Huang, Yiran Wang, Yujing Wang, Wenyu Wang, BenxuYang, Aiguo Feng, Chao Li, Shufen Wu, Changlu Wang.  (2025)  Study on the inhibitory effect and mechanism of Monascus yellow pigments (ankaflavin and monascinon) on porcine pancreatic lipase.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2025.128884]
40. Jiana Lin, Ying Chen, Gongke Li, Yuling Hu.  (2025)  Supramolecular calix[6]arene-COF with pocket-like cavities for host-guest recognition-based SERS detection of tryptamine and seafood freshness monitoring.  FOOD CHEMISTRY,      [PMID:41386090] [10.1016/j.foodchem.2025.147438]
41. Meng Zhang, Yanxiao Jiang, Qiong Wu, Hong Zhang, Kai Yu, Guangfeng Kan, Daqian Song, Jie Jiang.  (2025)  Online Electroextraction–NanoESI–MS for Rapid Analysis of Catecholamines in Urine.  ANALYTICAL CHEMISTRY,      [PMID:41405594] [10.1021/acs.analchem.5c05250]
42. Fan Zhihao, Shen Yu, Usman Muhammad, Su Kerui, Shahid Ayesha, Zhao Anqi, Li Xinyu, Zhang Beixiao, Xu Jingliang.  (2026)  Stabilizing Bioactive Components in Fresh Spirulina via Hydroxypropyl-β-Cyclodextrin-Loaded Curcumin: A Functional Preservation Approach.  Food and Bioprocess Technology,  19  (3): (155).  [PMID:] [10.1007/s11947-026-04255-8]
43. Jiaoqing Wei, Jiajia Wu, Xiaowen Hou, Rong Wang, Zhengyi Chen.  (2026)  Alkaline Hydrolysis coupled with Array Gas Membrane Separation device and HPLC-FL for the determination of Metformin in complex samples.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:] [10.1016/j.chroma.2026.466891]
44. Bairong Fu, Dongqin Tan, Jing Jin, Lei Tong, Longxing Wang, Yihou Peng, Ningbo Geng, Lidong Wu, Huilian Ma, Yuwen Ni, Jiping Chen.  (2026)  Fragmentation Pathways and Enhanced Detection Sensitivity of OH-PBDEs via LC-ESI-MS2: A Comprehensive Analytical Investigation.  ANALYTICAL CHEMISTRY,      [PMID:] [10.1021/acs.analchem.5c06791]
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