Darovasertib (LXS-196) - Moligand™, 10mM in DMSO , Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C theta, CAS No.1874276-76-2, Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C theta

CAS: 1874276-76-2 Cat. No.: D408066 Peso molecular: 472.47 Número EC: 975-583-6

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

IDE-196 | 2-​Pyrazinecarboxamide, 3-​amino-​N-​[3-​(4-​amino-​4-​methyl-​1-​piperidinyl)​-​2-​pyridinyl]​-​6-​[3-​(trifluoromethyl)​-​2-​pyridinyl]​-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Darovasertib (LXS-196) Darovasertib (LXS-196, IDE-196) is a selective inhibitor of protein kinase C (PKC) .
In vitro

In vivo

Cell Data

cell lines：MCF7 and T47D

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

IDE-196 | 2-​Pyrazinecarboxamide, 3-​amino-​N-​[3-​(4-​amino-​4-​methyl-​1-​piperidinyl)​-​2-​pyridinyl]​-​6-​[3-​(trifluoromethyl)​-​2-​pyridinyl]​-

Especificaciones y pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Darovasertib (LXS-196, IDE-196) is a selective inhibitor of protein kinase C (PKC).

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

INHIBITOR

Mecanismo de acción

Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C theta

Propiedades del producto

• ALogP: 1.6
• hba_count: 5
• Recuento HBD: 3
• Enlace rotable: 5

Nombres e identificadores

• Isómeros SMILES: CC1(CCN(CC1)C2=C(N=CC=C2)NC(=O)C3=NC(=CN=C3N)C4=C(C=CC=N4)C(F)(F)F)N
• Peso molecular: 472.47
• Reaxy-Rn: 29306963
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29306963&ln=

Objetivos asociados (humanos)

PRKCA Tchem Protein kinase C alpha type (2 Activities)

Discover Target: PRKCA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PRKCQ Tchem Protein kinase C theta type (2 Activities)

Discover Target: PRKCQ

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• DMSO (mg/ml) Solubilidad máxima: 22
• DMSO (mM) Solubilidad máxima: 46.5638029927826
• Agua (mg/ml) Solubilidad máxima: ＜1