DC 260126 - ≥98%(HPLC) , CAS No.346692-04-4

CAS: 346692-04-4 Cat. No.: D287987 Peso molecular: 307.38 Número EC: 809-022-2

GRADE & PURITY ≥98%(HPLC)

Synonyms

WNA69204 | C74786 | MFCD00784423 | N-(4-Butylphenyl)-4-fluorobenzene-1-sulfonamide | BDBM50196405 | N-(4-butylphenyl)-4-fluorobenzenesulfonamide | AKOS003265834 | SCHEMBL18058899 | BCP32685 | NCGC00387268-04 | HY-101906 | Oprea1_825888 | STK076838 | A8996

Storage

Conservar a -20°C

Shipped In

Hielera + almohadillas de hielo

Specifications

Sinónimos

WNA69204 | C74786 | MFCD00784423 | N-(4-Butylphenyl)-4-fluorobenzene-1-sulfonamide | BDBM50196405 | N-(4-butylphenyl)-4-fluorobenzenesulfonamide | AKOS003265834 | SCHEMBL18058899 | BCP32685 | NCGC00387268-04 | HY-101906 | Oprea1_825888 | STK076838 | A8996

Especificaciones y pureza

≥98%(HPLC)

Mecanismos bioquímicos y fisiológicos

El DC260126 es un antagonista selectivo del FFA1 (GPR40). En células CHO que expresan FFA1, el DC260126 bloquea la elevación de Ca2+ inducida por el ácido linoleico y la fosforilación de ERK (IC50 = 6028 μM), así como la secreción de insulina estimulada p

Condiciones de almacenamiento de almacenamiento

Conservar a -20°C

Enviado en

Hielera + almohadillas de hielo

Tipo de acción

INHIBITOR

Pureza

≥98%(HPLC)

Nombres e identificadores

• Pubchem Sid: 504762235
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504762235
• Sonrisas canónicas: CCCCC1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)F
• IUPAC Name: N-(4-butylphenyl)-4-fluorobenzenesulfonamide
• InChIKey: CNGHPXKWPGIDSK-UHFFFAOYSA-N
• INCHI: 1S/C16H18FNO2S/c1-2-3-4-13-5-9-15(10-6-13)18-21(19,20)16-11-7-14(17)8-12-16/h5-12,18H,2-4H2,1H3
• Isómeros SMILES: CCCCC1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)F
• Peso molecular: 307.38
• Reaxy-Rn: 24554546
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24554546&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Benzene and substituted derivatives
      • Subclass Sulfanilides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Benzene and substituted derivatives
• Subclass: Sulfanilides
• Intermediate Tree Nodes: Not available
• Direct Parent: Sulfanilides
• Alternative Parents: Benzenesulfonamides Benzenesulfonyl compounds Fluorobenzenes Organosulfonamides Aryl fluorides Aminosulfonyl compounds Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzenesulfonamide - Sulfanilide - Benzenesulfonyl group - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Organosulfonic acid amide - Aminosulfonyl compound - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Organosulfur compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Hydrocarbon derivative - Organic oxide - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Aromatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as sulfanilides. These are organic aromatic compounds containing a sulfanilide moiety, with the general structure RS(=O)(=O)NC1=CC=CC=C1.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

FFAR1 Tchem Free fatty acid receptor 1 (4763 Activities)

Discover Target: FFAR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FFAR4 Tchem G-protein coupled receptor 120 (2999 Activities)

Discover Target: FFAR4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Solvent:DMSO, Max Conc. mg/mL: 30.74, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 30.74, Max Conc. mM: 100
• Peso molecular: 307.400 g/mol
• XLogP3: 4.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 307.104 Da
• Monoisotopic Mass: 307.104 Da
• Topological Polar Surface Area: 54.600 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 391.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1