DEAE-Dextran , CAS No.9015-73-0

CAS: 9015-73-0 Cat. No.: D491446

Synonyms

Propyl 4-methylbenzoate|6976-69-8|9015-73-0|Colextran|Propyl4-methylbenzoate|Propyl 4-methylbenzoate #|SCHEMBL6057220|DTXSID40864168|LRNBWFXCDULFQF-UHFFFAOYSA-N|NSC24768|NSC-24768|AKOS008948190|Benzoic acid, 4-methyl-, propyl ester|Z53835724

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Overview

DEAE-dextran is a cationic derivative of dextran. IT is produced by introducing cationic (positively charged) diethylaminoethyl groups into selected dextran fractions. All batches are checked for molecular weight, degree of substitution and loss on drying. Aladdin produce DEAE-dextran from 4 kDa to 2000 kDa. DEAE-dextrans are supplied as a white hygroscopic powder.

Product specifications and parameters

sku	name	Molecular Weight
D491446-4 kDa	DEAE-Dextran	4 kDa
D491446-10 kDa	DEAE-Dextran	10 kDa
D491446-20 kDa	DEAE-Dextran	20 kDa
D491446-70 kDa	DEAE-Dextran	70 kDa
D491446-150 kDa	DEAE-Dextran	150 kDa
D491446-500 kDa	DEAE-Dextran	500 kDa
D491446-2000 kDa	DEAE-Dextran	2000 kDa

Structure

DEAE-dextrans are synthesised from controlled dextran fractions by reacting with DEAE-chloride. The predominant substituent is the single tertiary group (blue) but this may react further to yield a “tandem” group containing a quaternary amine as well as the tertiary amine. A titration curve reveals the proportions (Fig.2 in datafile).

Application

DEAE-dextrans are used in various areas, for example as adjuvants for vaccines, in transfection techniques and viral infectivity, and for stabilisation of proteins (enzymes).

Specifications

Synonyms

Propyl 4-methylbenzoate | 6976-69-8 | 9015-73-0 | Colextran | Propyl4-methylbenzoate | Propyl 4-methylbenzoate # | SCHEMBL6057220 | DTXSID40864168 | LRNBWFXCDULFQF-UHFFFAOYSA-N | NSC24768 | NSC-24768 | AKOS008948190 | Benzoic acid, 4-methyl-, propyl ester | Z53835724

Storage

Store at -20°C, Argon charged, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: CCCOC(=O)C1=CC=C(C=C1)C
• IUPAC Name: propyl 4-methylbenzoate
• InChIKey: LRNBWFXCDULFQF-UHFFFAOYSA-N
• INCHI: 1S/C11H14O2/c1-3-8-13-11(12)10-6-4-9(2)5-7-10/h4-7H,3,8H2,1-2H3
• Isomeric SMILES: CCCOC(=O)C1=CC=C(C=C1)C
• WGK Germany: 3
• RTECS: HH9250000
• Reaxy-Rn: 1944254
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1944254&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzoic acid esters
• Alternative Parents: Benzoyl derivatives Toluenes Carboxylic acid esters Monocarboxylic acids and derivatives Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzoate ester - Benzoyl - Toluene - Carboxylic acid ester - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as benzoic acid esters. These are ester derivatives of benzoic acid.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water
• Sensitivity: moisture sensitive
• Specific Rotation[α]: α20/D 145°±5°
• Molecular Weight: 178.230 g/mol
• XLogP3: 3.400
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 178.099 Da
• Monoisotopic Mass: 178.099 Da
• Topological Polar Surface Area: 26.300 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 157.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1