Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™,≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 23 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19.
| Sonrisas canónicas | CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O |
|---|---|
| IUPAC Name | N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide |
| InChIKey | UBQYURCVBFRUQT-UHFFFAOYSA-N |
| INCHI | 1S/C25H48N6O8/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34) |
| Isómeros SMILES | CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O |
| Peso molecular | 560.68 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Clase | Carboxylic acids and derivatives |
| Subclass | Carboxylic acid derivatives |
| Intermediate Tree Nodes | Carboxylic acid amides - Primary carboxylic acid amides - Hydroxamic acids |
| Direct Parent | Acetohydroxamic acids |
| Alternative Parents | Acetamides Amino acids and derivatives Propargyl-type 1,3-dipolar organic compounds Carboximidic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Acetamide - Acetohydroxamic acid - Amino acid or derivatives - Carboximidic acid - Carboximidic acid derivative - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Carbonyl group - Organic nitrogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Amine - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organic oxide - Aliphatic acyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as acetohydroxamic acids. These are organic compounds that contain a hydroxamic acid group carrying a methyl group attached to its carbon center. |
| External Descriptors | a hydroxamate siderophore |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Apr 06, 2026 | D651377 | |
| Certificate of Analysis | Nov 15, 2025 | D651377 | |
| Certificate of Analysis | Nov 15, 2025 | D651377 | |
| Certificate of Analysis | Nov 15, 2025 | D651377 | |
| Certificate of Analysis | Nov 15, 2025 | D651377 | |
| Certificate of Analysis | Jul 10, 2025 | D651377 | |
| Certificate of Analysis | Jul 10, 2025 | D651377 | |
| Certificate of Analysis | Jul 10, 2025 | D651377 | |
| Certificate of Analysis | Jul 10, 2025 | D651377 | |
| Certificate of Analysis | Jan 21, 2025 | D651377 | |
| Certificate of Analysis | Jan 21, 2025 | D651377 | |
| Certificate of Analysis | Jan 21, 2025 | D651377 | |
| Certificate of Analysis | Jan 21, 2025 | D651377 | |
| Certificate of Analysis | Jan 21, 2025 | D651377 | |
| Certificate of Analysis | Jan 21, 2025 | D651377 | |
| Certificate of Analysis | Jan 21, 2025 | D651377 | |
| Certificate of Analysis | Jan 21, 2025 | D651377 |
| Solubilidad | DMSO : 12.5 mg/mL (22.29 mM; ultrasonic and warming and heat to 60°C) |
|---|---|
| Peso molecular | 560.700 g/mol |
| XLogP3 | -2.100 |
| Hydrogen Bond Donor Count | 6 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 23 |
| Exact Mass | 560.353 Da |
| Monoisotopic Mass | 560.353 Da |
| Topological Polar Surface Area | 206.000 Ų |
| Heavy Atom Count | 39 |
| Formal Charge | 0 |
| Complexity | 739.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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| 2. Yahong Li, Junjin Zhu, Xin Zhang, Yuanyuan Li, Shu Zhang, Linxin Yang, Ruyi Li, Qianbing Wan, Xibo Pei, Junyu Chen, Jian Wang. (2023) Drug-Delivery Nanoplatform with Synergistic Regulation of Angiogenesis–Osteogenesis Coupling for Promoting Vascularized Bone Regeneration. ACS Applied Materials & Interfaces, [PMID:37010447] [10.1021/acsami.2c23107] |
| 3. Hao Chi, Guang Zhu, Yalin Yin, He Diao, Zicheng Liu, Shibo Sun, Zhaoming Guo, Weiping Xu, Jianqiang Xu, Changhao Cui, Xiao-Jin Xing, Kun Ma. (2022) Dual-Responsive multifunctional “core–shell” magnetic nanoparticles promoting Fenton reaction for tumor ferroptosis therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:35688287] [10.1016/j.ijpharm.2022.121898] |
| 4. Qingdong Li, Wenjuan Gao, Caiyun Zhang, Peng Wang, Xin Wang, Miao Yan, Wenguo Jiang, Zhengyan Wu, Pengfei Wei, Geng Tian, Guilong Zhang. (2022) A Biodegradable High-Efficiency Magnetic Nanoliposome Promotes Tumor Microenvironment-Responsive Multimodal Tumor Therapy Along with Switchable T2 Magnetic Resonance Imaging. ACS Applied Materials & Interfaces, [PMID:35583352] [10.1021/acsami.2c04158] |
| 5. Renyu Lin, Ziheng Zhang, Lingfeng Chen, Yunfang Zhou, Peng Zou, Chen Feng, Li Wang, Guang Liang. (2016) Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells. CANCER LETTERS, [PMID:27477901] [10.1016/j.canlet.2016.07.033] |
| 6. Zijuan Qi, Xiaofeng Huang, Jiajun Jing, Wenya Feng, Ming Xu, Li Yan, Ming Gao, Sijin Liu, Xue-Feng Yu. (2024) Amino-modified IONPs potentiates ferroptotic cell death due to the release of Fe ion in the lysosome. Journal of Environmental Sciences, [PMID:39306387] [10.1016/j.jes.2024.01.034] |
| 7. Suyue Gao, Tingyu Zheng, Kai Tian, Zou Jia, Wushuang Xu, Pingfan Wu, Shikun Cao, Ke Li, Lijun Wu. (2024) Application of Physically Crosslinked Hyaluronic Acid Hydrogel in the Treatment of Radiation-Induced Skin Injury. Advanced Therapeutics, [PMID:] [10.1002/adtp.202400165] |
| 8. Qingdong Li, Yuanyuan Cui, Zhenhong Xia, Wenjuan Gao, Jianmin Xiao, Zhen Zhao, Lei Yang, Guilong Zhang, Zhengyan Wu. (2025) Biodegradable nano-immune agonist for enhanced immunotherapy of melanoma via the synergistic action of cuproptosis and cGAS-STING enhanced immune response. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:40120375] [10.1016/j.jcis.2025.137326] |
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| 11. Yanyan Meng, Shaoqing Chen, Pengyin Li, Cheli Wang, Xinye Ni. (2024) Homologous tumor cell membrane-encapsulated methyl 5-aminolevulinate solid lipid nanoparticles for the precise localization of melanoma and sensitization by radiotherapy. MATERIALS & DESIGN, [PMID:] [10.1016/j.matdes.2024.112813] |
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| 14. Weikun Li, Xin Tan, Yanling Liang, Nuoya Chen, Diyi Feng, Yinghua Tao, Tao Liu, Xiaojing Wu, Huiqing Lu, Ling Liu, Feiling Feng, Liqin Ge. (2025) Multifunctional microneedle patch synergized with electrical stimulation to regulate microenvironment for enhanced healing of infected diabetic wounds. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.159255] |
| 15. Jian Yang, Haojie Yu, Li Wang, Xiaowei Liu, Yudi Huang, Yichuan Hong, Shuning Ren. (2024) Mussel-inspired near-infrared light-responsive gelatin-based hydrogels for enhancing MRSA-infected wound healing. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:38383251] [10.1016/j.ijbiomac.2024.129887] |
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| 21. Ruping Li, Yanxin Wu, Lvchen He, Ruotong Yang, Kaipei Luo, Fei Gao, Haipo Yuan, Yu Zheng, Yao He. (2025) Chinese herb-crosslinked polysaccharide hydrogel loading DFO accelerates diabetes wound healing. MATERIALS & DESIGN, [PMID:] [10.1016/j.matdes.2025.114128] |
| 22. Kun Liu, Wuyan Xu, Lin Li, Wendong Zhang, Wei Wen, Shan Ding, Mingxian Liu, Changren Zhou, Siming Li, Qingqi Meng, Binghong Luo. (2025) Bioinspired ECM-specific microenvironment scaffold: A multi-biomimetic strategy spatially guides osteochondral regeneration. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.164984] |
| 23. Zhu Liu, Xinlin Liu, Liwan He, Shengzhe Zhuang, Zhaoyang Li, Shuaipeng Feng, Luping Sha, Siling Wang, Qinfu Zhao. (2026) Se/S co-doped onion-derived CDs synergistically treat AKI by alleviating oxidative stress and enhancing iron chelation. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:] [10.1016/j.jcis.2026.140422] |
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