≥96% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Conservar a -20°C Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Presentación del producto
Deltarasin es un inhibidor de la interacción KRAS-PDEδ con una Kd de 38 nM para la unión a PDEδ purificada.
Descripción:
Valor IC50: 41±12 nM (unión a PDEδ en célula) [1]
Deltarasin es un inhibidor novedoso y de molécula pequeña que puede inhibir la interacción KRAS-PDEδ y deteriora la señalización oncogénica de KRAS.
Al interfer
| Pubchem Sid | 504772316 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772316 |
| Sonrisas canónicas | C1CNCCC1C(COC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3CC5=CC=CC=C5)N6C7=CC=CC=C7N=C6C8=CC=CC=C8 |
| IUPAC Name | 1-benzyl-2-[4-[(2S)-2-(2-phenylbenzimidazol-1-yl)-2-piperidin-4-ylethoxy]phenyl]benzimidazole |
| InChIKey | LTZKEDSUXKTTTC-KXQOOQHDSA-N |
| INCHI | 1S/C40H37N5O/c1-3-11-29(12-4-1)27-44-36-17-9-7-15-34(36)42-39(44)32-19-21-33(22-20-32)46-28-38(30-23-25-41-26-24-30)45-37-18-10-8-16-35(37)43-40(45)31-13-5-2-6-14-31/h1-22,30,38,41H,23-28H2/t38-/m1/s1 |
| Isómeros SMILES | C1CNCCC1[C@@H](COC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3CC5=CC=CC=C5)N6C7=CC=CC=C7N=C6C8=CC=CC=C8 |
| CAS alternativo | 1440898-82-7 |
| Peso molecular | 603.75 |
| Reaxy-Rn | 26566983 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=26566983&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Benzimidazoles |
| Subclass | Phenylbenzimidazoles |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylbenzimidazoles |
| Alternative Parents | Phenylimidazoles Phenoxy compounds Phenol ethers Alkyl aryl ethers Piperidines N-substituted imidazoles Heteroaromatic compounds Dialkylamines Azacyclic compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Phenylbenzimidazole - 2-phenylimidazole - Phenoxy compound - Phenol ether - Alkyl aryl ether - Monocyclic benzene moiety - N-substituted imidazole - Piperidine - Benzenoid - Heteroaromatic compound - Imidazole - Azole - Ether - Secondary aliphatic amine - Secondary amine - Azacycle - Hydrocarbon derivative - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Amine - Organic nitrogen compound - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as phenylbenzimidazoles. These are compounds containing a phenylbenzimidazole skeleton, which consists of a benzimidazole moiety where its imidazole ring is attached to a phenyl group. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 A2629098 | Certificate of Analysis | Feb 07, 2026 | D125721 |
| K2309373 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| K2309375 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| K2309376 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| K2309377 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| K2309378 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| K2309379 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| K2309380 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| K2309381 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| K2309409 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| K2309419 | Certificate of Analysis | Aug 12, 2025 | D125721 |
| Solubilidad | DMSO |
|---|---|
| Peso molecular | 603.800 g/mol |
| XLogP3 | 7.800 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 9 |
| Exact Mass | 603.3 Da |
| Monoisotopic Mass | 603.3 Da |
| Topological Polar Surface Area | 56.900 Ų |
| Heavy Atom Count | 46 |
| Formal Charge | 0 |
| Complexity | 923.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
