≥96% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Diallyl disulfide is an organosulfur compound that is naturally found in garlic ( Allium sativum ) and contributes to the pungent odor of crushed garlic.
Application：
Diallyl disulfide has been used:
· to study its effects in apoptosis induction and cell viability on different glioma cell lines;
· as a treatment and positive control to assess the anti-inflammatory regulation of nuclear factor erythroid-2 related factor-2 (Nrf2) in breast cancer cells;
· as a potential substrate compound to detect hydrogen sulfide (H2S) production via lead acetate/lead sulfide method.
| Sonrisas canónicas | C=CCSSCC=C |
|---|---|
| IUPAC Name | 3-(prop-2-enyldisulfanyl)prop-1-ene |
| InChIKey | PFRGXCVKLLPLIP-UHFFFAOYSA-N |
| INCHI | 1S/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2 |
| Isómeros SMILES | C=CCSSCC=C |
| WGK Alemania | 3 |
| RTECS | BB1000000 |
| Número ONU | 2810 |
| Peso molecular | 146.27 |
| Beilstein | 1699241 |
| Reaxy-Rn | 1699241 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1699241&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organosulfur compounds |
| Clase | Allyl sulfur compounds |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Allyl sulfur compounds |
| Alternative Parents | Dialkyldisulfides Sulfenyl compounds Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Allyl sulfur compound - Dialkyldisulfide - Organic disulfide - Sulfenyl compound - Hydrocarbon derivative - Aliphatic acyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as allyl sulfur compounds. These are compounds containing an allylsulfur group, with the general structure H2C(=CH2)CS. |
| External Descriptors | organic disulfide |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 I2418449 | Certificate of Analysis | Aug 10, 2024 | D432326 |
| I2418450 | Certificate of Analysis | Aug 10, 2024 | D432326 |
| I2418451 | Certificate of Analysis | Aug 10, 2024 | D432326 |
| I2418452 | Certificate of Analysis | Aug 10, 2024 | D432326 |
| I2418453 | Certificate of Analysis | Aug 10, 2024 | D432326 |
| I2418454 | Certificate of Analysis | Aug 10, 2024 | D432326 |
| I2418455 | Certificate of Analysis | Aug 10, 2024 | D432326 |
| I2418456 | Certificate of Analysis | Aug 10, 2024 | D432326 |
| Sensibilidad | Air and heat sensitive |
|---|---|
| Índice de refracción | 1.561 |
| Punto de inflamación (°F) | 143.6 °F |
| Punto de inflamación (°C) | 51°C |
| Punto de ebullición (°C) | 80-85°C |
| Peso molecular | 146.300 g/mol |
| XLogP3 | 2.200 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 5 |
| Exact Mass | 146.022 Da |
| Monoisotopic Mass | 146.022 Da |
| Topological Polar Surface Area | 50.600 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 58.900 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Shuaishuai Chen, Weiyu Guo, Huan Liu, Jiang Zheng, Dingyan Lu, Jia Sun, Chun Li, Chunhua Liu, Yonglin Wang, Yong Huang, Wen Liu, Yongjun Li, Ting Liu. (2023) Mechanistic study of cytochrome P450 enzyme-mediated cytotoxicity of psoralen and isopsoralen. FOOD AND CHEMICAL TOXICOLOGY, [PMID:37660943] [10.1016/j.fct.2023.114011] |
| 2. Ting Wang, Jing Deng, Ruijin Ran, Wenqiang Shi, Yunxia Gao, Xiang Ren, Jun Cao, Ming Zhang. (2022) In-situ forming PEG-engineering hydrogels with anti-fouling characteristics as an artificial vitreous body. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2022.137486] |
| 3. Tingting Li, Likun Ren, Dangfeng Wang, Minjie Song, Qiuying Li, Jianrong Li. (2020) Effect of allicin and its mechanism of action in purine removal in turbot. JOURNAL OF FOOD SCIENCE, 85 (10): (3562-3569). [PMID:32856309] [10.1111/1750-3841.15394] |
| 4. Zhang Bin, Zheng Zhenjia, Liu Nan, Liu Pengli, Qiu Zhichang, Qiao Xuguang. (2020) Effect of different combined mechanical and thermal treatments on the quality characteristics of garlic paste. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 58 (3): (1061-1071). [PMID:33678889] [10.1007/s13197-020-04620-1] |
| 5. Wu Tiaodi, Li Lin, Song Guangjie, Ran Miaomiao, Lu Xiaoquan, Liu Xiuhui. (2019) An ultrasensitive electrochemical sensor based on cotton carbon fiber composites for the determination of superoxide anion release from cells. MICROCHIMICA ACTA, 186 (3): (1-9). [PMID:30796529] [10.1007/s00604-019-3304-1] |
| 6. Liu Xin Chao, Zhou Ligang, Liu Qiyong, Liu Zhi Long. (2015) Laboratory Evaluation of Larvicidal Activity of the Essential oil of Allium tuberosum Roots and its Selected Major Constituent Compounds Against Aedes albopictus (Diptera: Culicidae). JOURNAL OF MEDICAL ENTOMOLOGY, 52 (3): (437-441). [PMID:26334818] [10.1093/jme/tjv016] |
| 7. Jia-yi Dou, Zhen-yu Cui, Mei-yan Xuan, Chong Gao, Zhao-Xu Li, Li-hua Lian, Hao-zhen Cui, Ji-xing Nan, Yan-ling Wu. (2024) Diallyl disulfide, the bioactive component of Allium species, ameliorates pulmonary fibrosis by mediating the crosstalk of farnesoid X receptor and yes-associated protein 1 signaling pathway. PHYTOTHERAPY RESEARCH, [PMID:38863408] [10.1002/ptr.8268] |
| 8. Jinlong Qin, Min Sun, Jiajing Cheng, Huici Jiang, Mingchen Lv, Jianxing Jing, Ran Chen, Zhen Fan, Jianzhong Du. (2024) Ultrasound-Responsive Hydrogel Incorporated with TGF-β Mimetic Peptides for Endometrium Recovery to Restore Fertility. ACS Applied Materials & Interfaces, [PMID:39415495] [10.1021/acsami.4c07290] |
| 9. Liangman Shi, Lunhui Zhu, Jialing Cao, Zhongyuan Zhang, Zhuqing Dai, Dajing Li, Lianfu Zhang, Cheng Yang. (2025) A novel mayonnaise product rich in cis-lutein with higher bioaccessibility using natural food ingredients and its textural properties, sensory quality and storage stability. FOOD CHEMISTRY, [PMID:40684574] [10.1016/j.foodchem.2025.145579] |
| 10. Yanbin Su, Xiaowei Ma, Ning Jiang, Qingsong Zhang, Mengjie Li, Yuan Li, Shuxin Li. (2018) Toxic target of trans-crotonaldehyde in mitochondria altered by diallyl disulfides for anti-myocardial ischemia. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:30075437] [10.1016/j.saa.2018.07.058] |
| 11. Zhuyu Yang, Zefan Chen, Weijia Zhang, Jinlin Wang, Fan Bai, Ruichang Gao, Yujin Li, Jian Li, Yuanhui Zhao, Xinxing Xu. (2025) Comparison of key odorants and sensory properties of various caviar with different breeding environments, processing conditions, and grades of quality. Food Chemistry-X, [PMID:41312202] [10.1016/j.fochx.2025.103272] |
| 12. Feng Liu, Feng Liu, Feng Liu, Zixuan Huang, Zixuan Huang, Jiao Li, Liming Li, Sheng Liu, Peng Li, Xiaowei Lei, Jiwei Zhang, Biqiang Jiang, Xuetao Gan, Jianlin Zhao. (2026) Mid-infrared micro-optics elements based on a flexible chalcogenide polymer. OPTICS LETTERS, 51 (4): (857-860). [PMID:41686935] [10.1364/OL.578637] |
| 13. Meina Jin, Xiaoyue Lun, Wei Mu, Yunhe Zhao, Zhengqun Zhang. (2026) Functional Characterization of Three Odorant-Binding Proteins in Sex Pheromones and Host Plant Volatiles Detection in Bradysia odoriphaga. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:41619224] [10.1021/acs.jafc.5c12660] |
