Dichloromethylenediphosphonic acid disodium salt - ≥98% , CAS No.22560-50-5

CAS: 22560-50-5 Cat. No.: D168759 Peso molecular: 288.86 Número EC: 245-078-9

GRADE & PURITY ≥98%

Synonyms

Cl2MDP | DTXCID40159526 | Clodronic acid disodium salt | CHEBI:59586 | Cl2MDP; Clodronic acid disodium magnesium salt; DMDP | Clodron | sodium (dichloro(phosphono)methyl)phosphonate | NCGC00261083-01 | HMS3261O17 | D 4434 | D4160 | Dichloromethane diphosp

Storage

Room temperature,Argon charged

Shipped In

Normal

Specifications

Sinónimos

Cl2MDP | DTXCID40159526 | Clodronic acid disodium salt | CHEBI:59586 | Cl2MDP; Clodronic acid disodium magnesium salt; DMDP | Clodron | sodium (dichloro(phosphono)methyl)phosphonate | NCGC00261083-01 | HMS3261O17 | D 4434 | D4160 | Dichloromethane diphosp

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

ATP-ADP transporter inhibitor. Inhibits bone resorption and soft tissue calcification. Encapsulated in liposomes, depletes macrophages in vivo . Induces apoptosis in osteoclasts.Analog of pyrophosphate ion that inhibits the osteoclastic activity leading t

Condiciones de almacenamiento de almacenamiento

Room temperature, Argon charged

Enviado en

Normal

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 488183128
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488183128
• Sonrisas canónicas: C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.[Na+].[Na+]
• IUPAC Name: disodium;[dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate
• InChIKey: HJKBJIYDJLVSAO-UHFFFAOYSA-L
• INCHI: 1S/CH4Cl2O6P2.2Na/c2-1(3,10(4,5)6)11(7,8)9;;/h(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2
• Isómeros SMILES: C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.[Na+].[Na+]
• WGK Alemania: 3
• RTECS: SZ7640700
• CAS alternativo: 88416-50-6
• Peso molecular: 288.86

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Organic phosphonic acids and derivatives
      • Subclass Bisphosphonates

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Organic phosphonic acids and derivatives
• Subclass: Bisphosphonates
• Intermediate Tree Nodes: Not available
• Direct Parent: Bisphosphonates
• Alternative Parents: Organic phosphonic acids Organic metal halides Organopnictogen compounds Organophosphorus compounds Organochlorides Organic sodium salts Organic oxides Hydrocarbon derivatives Alkyl chlorides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Bisphosphonate - Organophosphonic acid - Organic metal halide - Organic alkali metal salt - Alkyl chloride - Hydrocarbon derivative - Organic oxide - Organic sodium salt - Organic salt - Organophosphorus compound - Organochloride - Organopnictogen compound - Organohalogen compound - Organic oxygen compound - Alkyl halide - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as bisphosphonates. These are organic compounds containing two phosphonate groups linked together through a carbon atoms.
• External Descriptors: one-carbon compound - organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)

Discover Target: KMT2A

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rep Replicase polyprotein 1ab (378 Activities)

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Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Moisture sensitive
• Peso molecular: 288.850 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 287.85 Da
• Monoisotopic Mass: 287.85 Da
• Topological Polar Surface Area: 121.000 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 206.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3