Dicloxacillin Sodium - 10mM in DMSO , CAS No.343-55-5

CAS: 343-55-5 Cat. No.: D408692 Peso molecular: 492.31 Número EC: 206-444-3 PubChem CID: 23667628

GRADE & PURITY 10mM in DMSO

Synonyms

Veracillin, BRL1702 | 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt, hydrate (1:1:1), (2S,5R,6R)-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Dicloxacillin Sodium Dicloxacillin Sodium (Veracillin, BRL1702) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.
In vitro

Dicloxacillin Sodium is a narrow-spectrum β-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible Gram-positive bacteria. It is active against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins. Like other β-lactam antibiotics, dicloxacillin acts by inhibiting the synthesis of bacterial cell walls. It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall of Gram-positive bacteria. Dicloxacillin is insensitive to beta-lactamase (also known as penicillinase) enzymes secreted by many penicillin-resistant bacteria. The presence of the isoxazolyl group on the side-chain of the penicillin nucleus facilitates the β-lactamase resistance, since they are relatively intolerant of side-chain steric hindrance. Thus, it is able to bind to penicillin-binding proteins (PBPs) and inhibit peptidoglycan crosslinking, but is not bound by or inactivated by β-lactamases.

In vivo

Cell Data

cell lines：PC-3 cells

Concentrations：

Incubation Time：

Powder Purity:

Specifications

Sinónimos

Veracillin, BRL1702 | 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2, 6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3, 3-dimethyl-7-oxo-, sodium salt, hydrate (1:1:1), (2S, 5R, 6R)-

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Dicloxacillin Sodium (Veracillin, BRL1702) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Isómeros SMILES: CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)[O-].[Na+]
• PubChem CID: 23667628
• Peso molecular: 492.31

Propiedades químicas y físicas

• Punto de fusión (°C): 222-225°C