Diethyl dithio carbamic acid silver salt - ≥98%, used for It is used as a colorimetric reagent for the photometric determination of trace amounts of arsenic. It is also used for the photometric determination of antimony. It binds to Fe2+ to detect NO in t

CAS: 1470-61-7 Cat. No.: D113191 Peso molecular: 256.14 Beilstein Registry Number: 3718150 Número EC: 216-003-7

GRADE & PURITY ≥98%

Synonyms

AgDDTC | EINECS 253-895-7 | Silver, (diethyldithiocarbamato)- | silver;N,N-diethylcarbamodithioate | Silver, (diethylcarbamodithioato-S,S')- | D0490 | UNII-GVN001B86O | SCHEMBL900375 | Silver(1+) diethylcarbamodithioate | Silver, (diethylcarbamodithioato-

Storage

Store at 2-8°C

Shipped In

Wet ice

Descripción general

Sensitive to humid air and light. Insoluble in water. Easily soluble in pyridine and chloroform, sparingly soluble in ethanol, propanol, and benzene. Under certain conditions, it reacts with arsine to form a red product. Used as a colorimetric reagent for the photometric determination of trace arsenic. Also used for the photometric determination of antimony. It binds to Fe2+ to detect NO in the brain, kidneys, liver, and other tissues, while simultaneously directly measuring NO and pO2; as a copper chelating agent, it is also used for the ESR-based quantitative analysis of copper in biological materials; arsenic reagents are also inhibitors of superoxide dismutase, ascorbic acid oxidase, and other enzymes. Inhibits macrophage NO synthase.

Specifications

Sinónimos

AgDDTC | EINECS 253-895-7 | Silver, (diethyldithiocarbamato)- | silver;N, N-diethylcarbamodithioate | Silver, (diethylcarbamodithioato-S, S')- | D0490 | UNII-GVN001B86O | SCHEMBL900375 | Silver(1+) diethylcarbamodithioate | Silver, (diethylcarbamodithioato-

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Inhibits induction of macrophage nitric oxide synthase. Silver diethyldithiocarbamate (AgDDC) is used to estimate the level of arsenic in human

Aplicación

It is used as a colorimetric reagent for the photometric determination of trace amounts of arsenic. It is also used for the photometric determination of antimony. It binds to Fe2+ to detect NO in the brain, kidneys, liver, and other tissues, while simulta

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 488194207
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488194207
• Sonrisas canónicas: CCN(CC)C(=S)[S-].[Ag+]
• IUPAC Name: silver;N,N-diethylcarbamodithioate
• InChIKey: NSVHDIYWJVLAGH-UHFFFAOYSA-M
• INCHI: 1S/C5H11NS2.Ag/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1
• Isómeros SMILES: CCN(CC)C(=S)[S-].[Ag+]
• WGK Alemania: 3
• Peso molecular: 256.14
• Beilstein: 3718150
• Reaxy-Rn: 3718150
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3718150&ln=

Propiedades químicas y físicas

• Solubilidad: insoluble water
• Sensibilidad: Light sensitive
• Punto de fusión (°C): 172-175°C
• Peso molecular: 256.100 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 254.931 Da
• Monoisotopic Mass: 254.931 Da
• Topological Polar Surface Area: 36.300 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 73.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Yao Huang, Siyi Huang, Wensheng Liu, Fengyu Tian, Craig A. Grimes, Yi-Ge Zhou, Qingyun Cai.  (2023)  H2O2-responsive dual-peak ratiometric NIR-II fluorescent probe for in situ hepatic oxidative stress level monitoring.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2023.134823]

2. Jiale Cai, Guiping Hu, Lihua Hu, Junge Chen, Dan Chen, Dan Liu, Xiaolei Wang, Boxian Hu, Cheng Li.  (2023)  A CaCO3-based nanoplatform with sonodynamic and tumor microenvironment activated for combined in vitro cancer therapy.  Translational Oncology,      [PMID:37729741] [10.1016/j.tranon.2023.101771]

3. Yao Huang, Fengyu Tian, Leilei Sun, Chenhui Ji, Craig A. Grimes, Qingyun Cai.  (2023)  A glutathione-activated NIR-II fluorescent probe for precise localization of micrometastases.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2023.133457]

4. Kexin Bian, Weitao Yang, Yan Xu, Weiwei Zeng, Hui Wang, Hongying Liang, Tianming Cui, Zhuo Wang, Bingbo Zhang.  (2022)  Specific-Tuning Band Structure in Hetero-Semiconductor Nanorods to Match with Reduction of Oxygen Molecules for Low-Intensity Yet Highly Effective Sonodynamic/Hole Therapy of Tumors.  Small,  18  (31): (2202921).  [PMID:35801484] [10.1002/smll.202202921]

5. Yao Huang, Hongchao Geng, Zeming Wu, Leilei Sun, Chenhui Ji, Craig A. Grimes, Xinxin Feng, Qingyun Cai.  (2022)  An Ag2S@ZIF-Van nanosystem for NIR-II imaging of bacterial-induced inflammation and treatment of wound bacterial infection.  Biomaterials Science,  10  (14): (3972-3980).  [PMID:35708482] [10.1039/D2BM00550F]

6. Xiao-lin Hou, Xiang Dai, Jie Yang, Bin Zhang, Dong-hui Zhao, Chao-qing Li, Zhong-yuan Yin, Yuan-di Zhao, Bo Liu.  (2020)  Injectable polypeptide-engineered hydrogel depot for amplifying the anti-tumor immune effect induced by chemo-photothermal therapy.  Journal of Materials Chemistry B,  8  (37): (8623-8633).  [PMID:32821893] [10.1039/D0TB01370F]

7. Jia-Hua Zou, Li-Li Chen, Yong-Guo Hu, Dong Zhou, Yong Li, Bin Zhang, Xin-Yue Xu, Bo Liu, Jin-Xuan Fan, Yuan-Di Zhao.  (2024)  Ag2S quantum dot-based magnetic resonance/fluorescence dual-mode imaging nanoprobes for tumor diagnosis.  Biomaterials Science,      [PMID:39240013] [10.1039/D4BM01014K]

8. Yuanyuan Zhang, Weiwei Jin, Zhichao Deng, Bowen Gao, Yuanyuan Zhu, Junlong Fu, Chenxi Xu, Wenlong Wang, Ting Bai, Lianying Jiao, Hao Wu, Mingxin Zhang, Mingzhen Zhang.  (2025)  Metabolic reprogramming nanomedicine potentiates colon cancer sonodynamic immunotherapy by inhibiting the CD39/CD73/ADO pathway.  Acta Pharmaceutica Sinica B,      [PMID:40487643] [10.1016/j.apsb.2025.03.046]

9. Junli Yang, Xudong Xie, Qiaojian Duan, Yu Sun, Lin Yang, Bobin Mi, Peng Zhao, Kaiyong Cai.  (2025)  Bone-Targeted Multifunctional Nanoplatform Combining Osteoimmunoregulation and Mild Photothermal Effect to Promote Fracture Repair.  ACS Nano,      [PMID:41467338] [10.1021/acsnano.5c18379]