DIF-1 - ≥98% , CAS No.111050-72-7

CAS: 111050-72-7 Cat. No.: D275774 Peso molecular: 307.2

GRADE & PURITY ≥98%

Synonyms

Q27133348 | DIF 1 | Differentiation-inducing factor 1 | DIF-1 | DIF factor | C13H16Cl2O4 | DTXSID10149474 | Morphogen differentiation inducing factor (dictyostelium) | 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one | Dif-1 (dictyostelium) | 1-(

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Sinónimos

Q27133348 | DIF 1 | Differentiation-inducing factor 1 | DIF-1 | DIF factor | C13H16Cl2O4 | DTXSID10149474 | Morphogen differentiation inducing factor (dictyostelium) | 1-(3, 5-dichloro-2, 6-dihydroxy-4-methoxyphenyl)hexan-1-one | Dif-1 (dictyostelium) | 1-(

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Morphogen that induces differentiation of Dictyostelium discoideum . Inhibits proliferation of cancer cell lines by suppressing Wnt/ β-catenin signaling pathway. Also induces tumor cell differentiation.

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: CCCCCC(=O)C1=C(C(=C(C(=C1O)Cl)OC)Cl)O
• IUPAC Name: 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
• InChIKey: VUDQSRFCCHQIIU-UHFFFAOYSA-N
• INCHI: 1S/C13H16Cl2O4/c1-3-4-5-6-7(16)8-11(17)9(14)13(19-2)10(15)12(8)18/h17-18H,3-6H2,1-2H3
• Isómeros SMILES: CCCCCC(=O)C1=C(C(=C(C(=C1O)Cl)OC)Cl)O
• Peso molecular: 307.2
• Reaxy-Rn: 9789620
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9789620&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Carbonyl compounds
        • Level5 Ketones
          • Level6 Aryl ketones
            • Level7 Phenylketones
              • Level8 Alkyl-phenylketones

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Carbonyl compounds
• Intermediate Tree Nodes: Ketones - Aryl ketones - Phenylketones
• Direct Parent: Alkyl-phenylketones
• Alternative Parents: Butyrophenones Methoxyphenols Anisoles Aryl alkyl ketones Benzoyl derivatives Dichlorobenzenes Methoxybenzenes Resorcinols Phenoxy compounds P-chlorophenols O-chlorophenols Alkyl aryl ethers Aryl chlorides Vinylogous acids Organic oxides Organochlorides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Alkyl-phenylketone - Butyrophenone - Methoxyphenol - Anisole - Benzoyl - Phenoxy compound - 1,3-dichlorobenzene - 4-halophenol - 2-halophenol - 2-chlorophenol - 4-chlorophenol - Phenol ether - Resorcinol - Aryl alkyl ketone - Methoxybenzene - Alkyl aryl ether - Chlorobenzene - Phenol - Halobenzene - Monocyclic benzene moiety - Aryl halide - Aryl chloride - Benzenoid - Vinylogous acid - Ether - Organic oxide - Organohalogen compound - Organochloride - Hydrocarbon derivative - Aromatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
• External Descriptors: resorcinols - aromatic ketone - monomethoxybenzene - differentiation-inducing factor

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

Dictyostelium discoideum (81 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in DMSO to 50 mM
• Peso molecular: 307.170 g/mol
• XLogP3: 4.600
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 306.043 Da
• Monoisotopic Mass: 306.043 Da
• Topological Polar Surface Area: 66.800 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 284.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1