dihydrokainate - Moligand™ , Inhibitor of Excitatory amino acid transporter 2, CAS No.D609890, Inhibitor of Excitatory amino acid transporter 2

CAS: D609890 Cat. No.: D609890 PubChem CID: 73755099

GRADE & PURITY Moligand™

Storage

Room temperature

Specifications

Especificaciones y pureza

Moligand™

Condiciones de almacenamiento de almacenamiento

Room temperature

Grado

Moligand™

Tipo de acción

INHIBITOR

Mecanismo de acción

Inhibitor of Excitatory amino acid transporter 2

Nombres e identificadores

• Sonrisas canónicas: [O-]C(=O)C[C@H]1[C@H](CN[C@@H]1C(=O)[O-])C(C)C
• IUPAC Name: (2S,3S,4R)-3-(carboxylatomethyl)-4-(propan-2-yl)pyrrolidine-2-carboxylate
• InChIKey: JQPDCKOQOOQUSC-OOZYFLPDSA-L
• INCHI: 1S/C10H17NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h5-7,9,11H,3-4H2,1-2H3,(H,12,13)(H,14,15)/p-2/t6-,7+,9-/m0/s1
• Isómeros SMILES: CC(C)[C@H]1CN[C@@H]([C@H]1CC(=O)[O-])C(=O)[O-]
• PubChem CID: 73755099

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Kainoids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Kainoids
• Alternative Parents: Proline and derivatives L-alpha-amino acids Pyrrolidine carboxylic acids Dicarboxylic acids and derivatives Carboxylic acid salts Amino acids Dialkylamines Carboxylic acids Azacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Organic anions
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Kainoid skeleton - Proline or derivatives - Alpha-amino acid - Alpha-amino acid or derivatives - L-alpha-amino acid - Pyrrolidine carboxylic acid - Pyrrolidine carboxylic acid or derivatives - Dicarboxylic acid or derivatives - Pyrrolidine - Amino acid - Carboxylic acid salt - Azacycle - Organoheterocyclic compound - Secondary amine - Carboxylic acid - Secondary aliphatic amine - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Carbonyl group - Amine - Organic anion - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as kainoids. These are non-proteigenous amino acids with a structure characterized by the presence of a pyrrolidine ring bearing two dicarboxylic acid groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

SLC1A2 Tchem Excitatory amino acid transporter 2 (1 Activities)

Discover Target: SLC1A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)