Dihydrorhodamine 123 - ≥95% , CAS No.109244-58-8

CAS: 109244-58-8 Cat. No.: D115501 Peso molecular: 346.38 Número EC: 886-538-4

GRADE & PURITY ≥95%

Synonyms

AKOS015894985 | Methyl 2-(3,6-diamino-9H-xanthen-9-yl)benzoate | dihydrorhodamine-123 | FT-0624967 | C21H18N2O3 | MFCD04221428 | A11886 | DHR 123 | DTXSID40148859 | HY-101894 | SCHEMBL3682802 | J-100130 | Benzoic acid, 2-(3,6-diamino-9H-xanthen-9-yl)-, me

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Peroxidase substrate

Specifications

Sinónimos

AKOS015894985 | Methyl 2-(3, 6-diamino-9H-xanthen-9-yl)benzoate | dihydrorhodamine-123 | FT-0624967 | C21H18N2O3 | MFCD04221428 | A11886 | DHR 123 | DTXSID40148859 | HY-101894 | SCHEMBL3682802 | J-100130 | Benzoic acid, 2-(3, 6-diamino-9H-xanthen-9-yl)-, me

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

二氢罗丹明123可检测单细胞水平的超氧离子 可用于在呼吸爆发事件中探测中性粒细胞超氧化物的产生。也用于检测巨噬细胞和人类精子的氧化应激情况。 二氢罗丹明123可用于检测ROS（活性氧物质）。ROS的存在可将二氢罗丹明123氧化成荧光衍生物罗丹明123。该反应可在过氧化物酶或类似催化剂存在下发生。

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 504756596
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504756596
• Sonrisas canónicas: COC(=O)C1=CC=CC=C1C2C3=C(C=C(C=C3)N)OC4=C2C=CC(=C4)N
• IUPAC Name: methyl 2-(3,6-diamino-9H-xanthen-9-yl)benzoate
• InChIKey: FNEZBBILNYNQGC-UHFFFAOYSA-N
• INCHI: 1S/C21H18N2O3/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20/h2-11,20H,22-23H2,1H3
• Isómeros SMILES: COC(=O)C1=CC=CC=C1C2C3=C(C=C(C=C3)N)OC4=C2C=CC(=C4)N
• WGK Alemania: 3
• Peso molecular: 346.38
• Reaxy-Rn: 5989965
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5989965&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Benzopyrans
      • Subclass 1-benzopyrans
        • Level5 Dibenzopyrans
          • Level6 Xanthenes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Dibenzopyrans
• Direct Parent: Xanthenes
• Alternative Parents: Diarylethers Benzoic acid esters Benzoyl derivatives Methyl esters Amino acids and derivatives Oxacyclic compounds Monocarboxylic acids and derivatives Primary amines Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Xanthene - Diaryl ether - Benzoate ester - Benzoic acid or derivatives - Benzoyl - Monocyclic benzene moiety - Benzenoid - Methyl ester - Amino acid or derivatives - Carboxylic acid ester - Carboxylic acid derivative - Oxacycle - Ether - Monocarboxylic acid or derivatives - Primary amine - Organic nitrogen compound - Amine - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: DMSO: >5 mg/mL
• Sensibilidad: Light sensitive
• Peso molecular: 346.400 g/mol
• XLogP3: 3.400
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 346.132 Da
• Monoisotopic Mass: 346.132 Da
• Topological Polar Surface Area: 87.600 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 487.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

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