Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate - ≥95% , CAS No.43067-01-2

CAS: 43067-01-2 Cat. No.: D350035 Peso molecular: 335.78 Número EC: 642-061-1

GRADE & PURITY ≥95%

Synonyms

Amlodipine besilate impurity G | Oprea1_609948 | 3,5-PYRIDINEDICARBOXYLIC ACID, 4-(2-CHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-, 3,5-DIMETHYL ESTER | FT-0667343 | STK387362 | EU-0035198 | SCHEMBL3035724 | SR-01000403200-1 | REIGLQUFMMOAFU-UHFFFAOYSA-N | SR-0

Storage

Store at 2-8°C

Shipped In

Wet ice

Descripción general

Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (Amlodipine EP Impurity G) is an Amlodipine Besilate impurity.

Specifications

Sinónimos

Amlodipine besilate impurity G | Oprea1_609948 | 3, 5-PYRIDINEDICARBOXYLIC ACID, 4-(2-CHLOROPHENYL)-1, 4-DIHYDRO-2, 6-DIMETHYL-, 3, 5-DIMETHYL ESTER | FT-0667343 | STK387362 | EU-0035198 | SCHEMBL3035724 | SR-01000403200-1 | REIGLQUFMMOAFU-UHFFFAOYSA-N | SR-0

Especificaciones y pureza

≥95%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

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Tipo de acción

ANTAGONIST

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 504760070
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504760070
• Sonrisas canónicas: CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2Cl)C(=O)OC
• IUPAC Name: dimethyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• InChIKey: REIGLQUFMMOAFU-UHFFFAOYSA-N
• INCHI: 1S/C17H18ClNO4/c1-9-13(16(20)22-3)15(11-7-5-6-8-12(11)18)14(10(2)19-9)17(21)23-4/h5-8,15,19H,1-4H3
• Isómeros SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2Cl)C(=O)OC
• Peso molecular: 335.78
• Reaxy-Rn: 3595219
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3595219&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Pyridines and derivatives
      • Subclass Hydropyridines
        • Level5 Dihydropyridines
          • Level6 Dihydropyridinecarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Pyridines and derivatives
• Subclass: Hydropyridines
• Intermediate Tree Nodes: Dihydropyridines
• Direct Parent: Dihydropyridinecarboxylic acids and derivatives
• Alternative Parents: Chlorobenzenes Dicarboxylic acids and derivatives Aryl chlorides Vinylogous amides Methyl esters Enoate esters Amino acids and derivatives Enamines Dialkylamines Azacyclic compounds Organopnictogen compounds Organochlorides Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Dihydropyridinecarboxylic acid derivative - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Dicarboxylic acid or derivatives - Vinylogous amide - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Methyl ester - Amino acid or derivatives - Carboxylic acid ester - Carboxylic acid derivative - Azacycle - Secondary aliphatic amine - Secondary amine - Enamine - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Amine - Carbonyl group - Organic oxide - Organooxygen compound - Organopnictogen compound - Organonitrogen compound - Organohalogen compound - Organochloride - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as dihydropyridinecarboxylic acids and derivatives. These are compounds containing a dihydropyridine moiety bearing a carboxylic acid group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
• Punto de fusión (°C): 191-193°C
• Peso molecular: 335.800 g/mol
• XLogP3: 3.000
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 335.092 Da
• Monoisotopic Mass: 335.092 Da
• Topological Polar Surface Area: 64.599 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 529.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Hongjian Huang, Yan Fang, Yunxiang Weng, Haiqing Liu.  (2023)  Photo-/electro-chromic underwater adhesive coacervate from self-assembly of zwitterions and polyoxometalate.  Materials Today Chemistry,      [PMID:] [10.1016/j.mtchem.2023.101670]

2. Zhi-Ang Liu, Ya-Nan Zuo, Yinghui Xia, Jing Sun, Shuyun Zhu.  (2022)  Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system.  Analytical Methods,  14  (37): (3632-3637).  [PMID:36052693] [10.1039/D2AY01019D]

3. Zeming Huang, Yin Gao, Zhengyu Huang, Donglin Chen, Jiahui Sun, Li Zhou.  (2021)  Sulfur quantum dots: A novel fluorescent probe for sensitive and selective detection of Fe3+ and phytic acid.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2021.106656]