Dimethyl-bisphenol A - ≥99% , CAS No.1568-83-8

CAS: 1568-83-8 Cat. No.: D275158 Peso molecular: 256.34

GRADE & PURITY ≥99%

Synonyms

HIF-1alpha inhibitor | KSC-7-226 | BISPHENOLADIMETHYLETHER | DTXSID30347091 | 1-methoxy-4-[2-(4-methoxyphenyl)propan-2-yl]benzene | MFCD00984727 | OJYIBEYSBXIQOP-UHFFFAOYSA-N | 1-Methoxy-4-[1-(4-methoxyphenyl)-1-methylethyl]benzene # | HY-115746 | AKOS003

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

HIF-1alpha inhibitor | KSC-7-226 | BISPHENOLADIMETHYLETHER | DTXSID30347091 | 1-methoxy-4-[2-(4-methoxyphenyl)propan-2-yl]benzene | MFCD00984727 | OJYIBEYSBXIQOP-UHFFFAOYSA-N | 1-Methoxy-4-[1-(4-methoxyphenyl)-1-methylethyl]benzene # | HY-115746 | AKOS003

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

HIF-1α inhibitor that promotes degradation of HIF-1α protein by dissociating Hsp90 from HIF-1α. Inhibits steroidogenesis and down regulates rate-limiting enzymes (StAR) in the estradiol biosynthesis pathway.Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥99%

Nombres e identificadores

• Pubchem Sid: 504759558
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504759558
• Sonrisas canónicas: CC(C)(C1=CC=C(C=C1)OC)C2=CC=C(C=C2)OC
• IUPAC Name: 1-methoxy-4-[2-(4-methoxyphenyl)propan-2-yl]benzene
• InChIKey: OJYIBEYSBXIQOP-UHFFFAOYSA-N
• INCHI: 1S/C17H20O2/c1-17(2,13-5-9-15(18-3)10-6-13)14-7-11-16(19-4)12-8-14/h5-12H,1-4H3
• Isómeros SMILES: CC(C)(C1=CC=C(C=C1)OC)C2=CC=C(C=C2)OC
• Peso molecular: 256.34
• Reaxy-Rn: 1879104
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1879104&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Benzene and substituted derivatives
      • Subclass Diphenylmethanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Benzene and substituted derivatives
• Subclass: Diphenylmethanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Diphenylmethanes
• Alternative Parents: Phenylpropanes Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Diphenylmethane - Phenylpropane - Phenoxy compound - Methoxybenzene - Phenol ether - Anisole - Alkyl aryl ether - Ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in ethanol to 75 mM and in DMSO to 100 mM
• Peso molecular: 256.339 g/mol
• XLogP3: 4.000
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 256.146 Da
• Monoisotopic Mass: 256.146 Da
• Topological Polar Surface Area: 18.500 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 232.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Xiaoye Cheng, Yijin Jiang, Xu Zhao, Nana Ma, Xiangzhen Shen.  (2024)  Regulation of lactate accumulation in bovine mammary epithelial cells by LPS-induced HIF-1α/MCT1 pathway.  MICROBIAL PATHOGENESIS,      [PMID:39725042] [10.1016/j.micpath.2024.107261]