Diphenylcyclopropenone(DPC) - Moligand™, 10 mM in DMSO , CAS No.886-38-4

CAS: 886-38-4 Cat. No.: D1500510 Peso molecular: 206.24 Beilstein Registry Number: 608049 Número EC: 212-948-4
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Argon charged,Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
D1500510-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
58,90US$
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Argon charged,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Diphenylcyclopropenone (Diphencyprone) is a potent hapten acting as a topical immunomodulatory agent, which induces an allergic contact dermatitis. Diphenylcyclopropenone induces an increase of cell-surface thiols in cells of a human monocytic cell line, THP-1. Diphenylcyclopropenone acts on the autoreactive T-lymphocytes within the follicular milieu to induce Apoptosis . Diphenylcyclopropenone can be used for alopecia areata research .

Specifications

Especificaciones y pureza
Moligand™, 10 mM in DMSO
Condiciones de almacenamiento de almacenamiento
Argon charged, Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Nombres e identificadores
Isómeros SMILES C1=CC=C(C=C1)C2=C(C2=O)C3=CC=CC=C3
WGK Alemania 3
Peso molecular 206.24
Beilstein 608049
Reaxy-Rn 608049
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=608049&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Punto de fusión (°C)117-121°C
Citations of This Product
Referencias
1. Zhi-Jun Zhang, Han-Yu Shao, Chuan Liu, Hao-Lin Song, Xiao-Bo Wu, De-Li Cao, Meixuan Zhu, Yuan-Yuan Fu, Juan Wang, Yong-Jing Gao.  (2023)  Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR+ neurons.  EMBO REPORTS,      [PMID:37522391] [10.15252/embr.202256098]
2. Jing Peng-Bo, Cao De-Li, Li Si-Si, Zhu Meixuan, Bai Xue-Qiang, Wu Xiao-Bo, Gao Yong-Jing.  (2017)  Chemokine Receptor CXCR3 in the Spinal Cord Contributes to Chronic Itch in Mice.  Neuroscience Bulletin,  34  (1): (54-63).  [PMID:28401489] [10.1007/s12264-017-0128-z]
3. Ni An, Guzailinuer Yasen, Ximu Li, Xianbao Shi, Yongjun Wang, Hongzhuo Liu.  (2025)  Nanoparticle Adjuvants Incorporating Haptens Drive Potent Immune Tolerance to Accelerate Hair Regrowth.  ACS Applied Materials & Interfaces,      [PMID:39818727] [10.1021/acsami.4c17068]
4. Xuxing Pei, Bing Li, Xiaodong Xu, Hui Zhang.  (2024)  Spinal Caspase-6 Contributes to Intrathecal Morphine-induced Acute Itch and Contact Dermatitis-induced Chronic Itch Through Regulating the Phosphorylation of Protein Kinase Mζ in Mice.  NEUROSCIENCE,      [PMID:38176610] [10.1016/j.neuroscience.2023.12.015]
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