DL-erythro/threo Sphinganine (d18:0) - ≥98% , CAS No.3102-56-5

CAS: 3102-56-5 Cat. No.: D274924 Peso molecular: 301.51

GRADE & PURITY ≥98%

Synonyms

Dihydrosphingosine | DL-dihydrosphingosine | FT-0634669 | 2-azanyloctadecane-1,3-diol | J-006709 | NCGC00015362-03 | MLS000028682 | SMR000058664 | HMS2232A24 | rel-2R-amino-1,3S-octadecanediol

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

DL-erythro-Dihydrosphingosine is a potent inhibitor of PKC and phospholipase A2 (PLA2).

Specifications

Sinónimos

Dihydrosphingosine | DL-dihydrosphingosine | FT-0634669 | 2-azanyloctadecane-1, 3-diol | J-006709 | NCGC00015362-03 | MLS000028682 | SMR000058664 | HMS2232A24 | rel-2R-amino-1, 3S-octadecanediol

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

PKC inhibitor (IC 50 = 2-4 µM). Involved in ceramide biosynthesis and mitogenesis. Active in vitro.

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: OC[C@@H](N)[C@@H](O)CCCCCCCCCCCCCCC
• IUPAC Name: 2-aminooctadecane-1,3-diol
• InChIKey: OTKJDMGTUTTYMP-UHFFFAOYSA-N
• INCHI: 1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3
• Isómeros SMILES: CCCCCCCCCCCCCCCC(C(CO)N)O
• Peso molecular: 301.51
• Reaxy-Rn: 1772584
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1772584&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Clase Organonitrogen compounds
      • Subclass Amines
        • Level5 Alkanolamines
          • Level6 1,2-aminoalcohols

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Clase: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Alkanolamines
• Direct Parent: 1,2-aminoalcohols
• Alternative Parents: Secondary alcohols Primary alcohols Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Secondary alcohol - 1,2-aminoalcohol - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Primary alcohol - Organooxygen compound - Primary aliphatic amine - Alcohol - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as 1,2-aminoalcohols. These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom.
• External Descriptors: a sphinganine C18

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in DMSO
• Peso molecular: 301.500 g/mol
• XLogP3: 5.800
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 16
• Exact Mass: 301.298 Da
• Monoisotopic Mass: 301.298 Da
• Topological Polar Surface Area: 66.500 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 200.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1