DL-Glutamic Acid - ≥92%(HPLC) , CAS No.617-65-2

CAS: 617-65-2 Cat. No.: S161021 Peso molecular: 147.13 Beilstein Registry Number: 4(3)1550 Número EC: 210-522-2

GRADE & PURITY ≥92%(HPLC)

Synonyms

H-DL-Glu-OH | AKOS000118798 | WLN: QVYZ2VQ -L | 61LJO5I15S | CHEBI:53373 | DL-Glutamicacid | glutamic acid-2,3,3,4,4-d5 | H-DL-Glu-OH | A854538 | Glutaminsaeure | NSC 206301 | SCHEMBL2201 | bmse001013 | DL-Glutamic-2,3,3,4,4-d5 Acid | GLUTAMIC ACID, L-, [

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. Glutamic Acid is also a key molecule in cellular metabolism. DL-Glutamic acid is used ito study its mechanisms of crystal formation and self-assembly on surfaces and copolymer development.

Specifications

Sinónimos

H-DL-Glu-OH | AKOS000118798 | WLN: QVYZ2VQ -L | 61LJO5I15S | CHEBI:53373 | DL-Glutamicacid | glutamic acid-2, 3, 3, 4, 4-d5 | H-DL-Glu-OH | A854538 | Glutaminsaeure | NSC 206301 | SCHEMBL2201 | bmse001013 | DL-Glutamic-2, 3, 3, 4, 4-d5 Acid | GLUTAMIC ACID, L-, [

Especificaciones y pureza

≥92%(HPLC)

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥92%(HPLC)

Nombres e identificadores

• Pubchem Sid: 504750397
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504750397
• Sonrisas canónicas: C(CC(=O)O)C(C(=O)O)N
• IUPAC Name: 2-aminopentanedioic acid
• InChIKey: WHUUTDBJXJRKMK-UHFFFAOYSA-N
• INCHI: 1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)
• Isómeros SMILES: C(CC(=O)O)C(C(=O)O)N
• RTECS: LZ9648000
• Peso molecular: 147.13
• Beilstein: 4(3)1550
• Reaxy-Rn: 1723799
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1723799&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Glutamic acid and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Glutamic acid and derivatives
• Alternative Parents: Alpha amino acids Amino fatty acids Dicarboxylic acids and derivatives Amino acids Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Glutamic acid or derivatives - Alpha-amino acid - Amino fatty acid - Dicarboxylic acid or derivatives - Fatty acid - Fatty acyl - Amino acid - Carboxylic acid - Organic oxide - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Amine - Organic nitrogen compound - Hydrocarbon derivative - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as glutamic acid and derivatives. These are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: alpha-amino acid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in water (miscible), HCl, ether (sparingly), ethanol (sparingly), and petroleum ether (sparingly).
• Sensibilidad: heat＆air sensitive
• Punto de fusión (°C): 194 °C
• Peso molecular: 147.130 g/mol
• XLogP3: -3.700
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 147.053 Da
• Monoisotopic Mass: 147.053 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 145.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Donglu Fang, Panrong Zhang, Benard Muinde Kimatu, Fei Pei, Wenjian Yang, Qiuhui Hu, Ning Ma.  (2023)  Metabolomic approach: Postharvest mushroom (Agaricus bisporus) browning inhibited by nanocomposite packaging materials.  Food Packaging and Shelf Life,      [PMID:] [10.1016/j.fpsl.2023.101186]

2. Zhihong Wang, Taifeng Li, Ruisheng Li, Bo Cao, Shiyuan Wang, Xiaofei Fei, Chunyu Li, Guohui Li.  (2023)  Sijunzi Tang improves gefitinib resistance by regulating glutamine metabolism.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:37738796] [10.1016/j.biopha.2023.115438]

3. Yunxi Huang, Zhanling Ding, Yutong Li, Fengna Xi, Junjie Liu.  (2023)  Magnetic Nanozyme Based on Loading Nitrogen-Doped Carbon Dots on Mesoporous Fe3O4 Nanoparticles for the Colorimetric Detection of Glucose.  MOLECULES,  28  (12): (4573).  [PMID:37375128] [10.3390/molecules28124573]

4. Zhifeng Cai, Yi Zhang, Meiling Jin, Meiling Hao, Huijuan Yang, Yang Peng, Jingwen Lu, Yaofang Zhang, Jiaxu Dong, Jiali Ren, Ran Zhang, Ya Wang.  (2023)  Preparation of blue fluorescent copper nanoclusters for sensitive and selective sensing of apigenin in pharmaceutical samples.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:37267837] [10.1016/j.saa.2023.122940]

5. Zhifeng Cai, Yi Zhang, Yiming Zhang, Yongjie Bai, Jiayue Huang, Zijing Guo, Huangjing Bao, Jiayi Zhang.  (2023)  One-pot simple preparation of bright blue emitting copper nanoclusters for sensitive detection of chrysin via inner filter effect.  JOURNAL OF LUMINESCENCE,      [PMID:] [10.1016/j.jlumin.2023.119781]

6. B.-B. Chen, S. Chang, M.-L. Liu, J. Lv, Y. Wang, R.-C. Qian, D.-W. Li.  (2022)  Phosphorescent LaCO3OH core-satellite superstructures with highly efficient photocatalysis.  Materials Today Sustainability,      [PMID:] [10.1016/j.mtsust.2022.100290]

7. Yao Fan, Siying Che, Lei Zhang, Chunsong Zhou, Haiyan Fu, Yuanbin She.  (2022)  Dual channel sensor array based on ZnCdSe QDs – KMnO4: An effective tool for analysis of catechins and green teas.  FOOD RESEARCH INTERNATIONAL,      [PMID:36076421] [10.1016/j.foodres.2022.111734]

8. Xuemei Dong, Minhui Wang, Yecang Tang.  (2022)  Green synthesis of fluorescent carbon nanospheres from chrysanthemum as a multifunctional sensor for permanganate, Hg(II), and captopril.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:35063823] [10.1016/j.saa.2022.120886]

9. Chaoqun Lin, Shiying Huang, Jianfeng Zhang, Huaitao Yuan, Tuchao Yao, Lukui Chen.  (2021)  Dl-3-N-Butylphthalide Attenuates Hypoxic Injury of Neural Stem Cells by Increasing Hypoxia-Inducible Factor-1alpha.  Journal of Stroke & Cerebrovascular Diseases,      [PMID:34837757] [10.1016/j.jstrokecerebrovasdis.2021.106221]

10. Na Wei, Meng-Xia Wei, Bo-Hui Huang, Xiao-Feng Guo, Hong Wang.  (2020)  One-pot facile synthesis of green-emitting fluorescent silicon quantum dots for the highly selective and sensitive detection of nitrite in food samples.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2020.108848]

11. Dingding Duan, Yaping Ding, Li Li, Guohong Ma.  (2020)  Rapid quantitative detection of melatonin by electrochemical sensor based on carbon nanofibers embedded with FeCo alloy nanoparticles.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,      [PMID:] [10.1016/j.jelechem.2020.114422]

12. Chao-Qun Lin, Lu-Kui Chen.  (2020)  Cerebral dopamine neurotrophic factor promotes the proliferation and differentiation of neural stem cells in hypoxic environments.  Neural Regeneration Research,      [PMID:32394962] [10.4103/1673-5374.282262]

13. Yuan Meng-Meng, Zou Jiao, Huang Zhao-Ning, Peng Dong-Ming, Yu Jin-Gang.  (2020)  PtNPs-GNPs-MWCNTs-β-CD nanocomposite modified glassy carbon electrode for sensitive electrochemical detection of folic acid.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  412  (11): (2551-2564).  [PMID:32162086] [10.1007/s00216-020-02488-w]

14. Jun Wang, Luyi Zhu, Weilin Zhang, Zhenbo Wei.  (2018)  Application of the voltammetric electronic tongue based on nanocomposite modified electrodes for identifying rice wines of different geographical origins.  ANALYTICA CHIMICA ACTA,      [PMID:30661592] [10.1016/j.aca.2018.11.016]

15. Zhenbo Wei, Yanan Yang, Luyi Zhu, Weilin Zhang, Jun Wang.  (2018)  Application of novel nanocomposite-modified electrodes for identifying rice wines of different brands.  RSC Advances,  8  (24): (13333-13343).  [PMID:35542510] [10.1039/C8RA00164B]

16. Qing Xiong, Jing Jin, Liqiong Lv, Zhisi Bu, Shengqiang Tong.  (2018)  Chiral ligand exchange countercurrent chromatography: Enantioseparation of amino acids.  JOURNAL OF SEPARATION SCIENCE,  41  (6): (1479-1488).  [PMID:29323783] [10.1002/jssc.201701117]

17. Shouhui Yi, Bo Yang, Rongqiang Liao.  (2017)  Synthesis, characterization, and cytotoxicity studies of novel pendant polymers: Amino acid β-cyclodextrin-conjugated poly(ε-lysine) derivatives.  INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION,      [PMID:] [10.1080/1023666X.2017.1283089]

18. Xue-jia Zhai, Fen Chen, Chao-ran Zhu, Yong-ning Lu.  (2015)  A simple LC-MS/MS method for quantitative analysis of underivatized neurotransmitters in rats urine: assay development, validation and application in the CUMS rat model.  BIOMEDICAL CHROMATOGRAPHY,  29  (11): (1737-1743).  [PMID:25944269] [10.1002/bmc.3487]

19. Yuting Liu, Zixu Zhang, Dawei Yin, Yukai Huang, Ying Liu, Jinze Li, Ruilin Zheng.  (2024)  A simple and highly selective chalcone fluorescent chemical sensor for the detection of tryptophane.  POLYHEDRON,      [PMID:] [10.1016/j.poly.2024.117303]

20. Yuxin He, Hecun Zou, Xinhui Jiang, Yanrui Wei, Siqiao Li, Tong Wu, Zhengwei Zhang.  (2024)  A smartphone-assisted fluorescent sensor using Eu/Tb-MOF nanorods for ultrasensitive and visual monitoring of carbendazim in food samples.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.112602]

21. Tiantian Dong, Haiyan Zhang, Lingqiang Kong, Zhen Liu, Hongchao Ma.  (2024)  Bioinspired coassembly of peptide, imidazolecarboxaldehyde, and copper for nanozyme with laccase-like activity for colorimetric detection of epinephrine.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2024.135445]

22. Zhifeng Cai, Qi Liang, Yutong Wang, Xiao Wang, Lulu Jing, Yajie Cheng, Jinqi Liu, Zixuan Jia.  (2024)  Bright, blue fluorescent carbon dots for sensitive and selective detection of folic acid.  CHEMICAL PHYSICS,      [PMID:] [10.1016/j.chemphys.2024.112216]

23. Hang Su, Shuo Huang, Xin Gao, He Bai, Haopeng Zhang, Long Li, Lei Zhao, Hongyan Yue.  (2024)  Nanoassembly of l-Threonine on Helical Carbon Tubes for Electrochemical Chiral Detection of l-Cysteine.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.4c02828]

24. Man Du, Meimei Song, Die Wu, Yue Zhang, Haiwen Song, Haijun Lv, Aibing Ke, Hongxia Du, Shuchun Zhao.  (2024)  Novel fluorescent nanoplatform for all-in-one sensing and removal of acrolein: An ultrasensitive probe to evaluate its removal efficiency.  FOOD CHEMISTRY,      [PMID:39094348] [10.1016/j.foodchem.2024.140667]

25. Hua Liu, Xiaohui Liu, Lingzhi Wang, Birong Zeng, Qingyun Zhao, Weiang Luo, Yiting Xu, Conghui Yuan, Lizong Dai.  (2025)  Organic-inorganic hybrid epoxy vitrimers with excellent thermal-mechanical stability based on carboxylic-acid type carbon dots as curing agent: Flame retardancy and reprocessing.  COMPOSITES PART B-ENGINEERING,      [PMID:] [10.1016/j.compositesb.2025.112316]

26. Chen Jinglin, Wei Yumeng, Li Nong, Pi Chao, Zhao Wenmei, Zhong Yueting, Li Wen, Shen Hongping, Yang Yan, Zheng Wenwu, Jiang Jun, Liu Zerong, Liu Kezhi, Zhao Ling.  (2024)  Preliminary Investigation Into the Antidepressant Effects of a Novel Curcumin Analogue (CACN136) In Vitro and In Vivo.  MOLECULAR NEUROBIOLOGY,      [PMID:39080204] [10.1007/s12035-024-04363-6]

27. Yuxin He, Hecun Zou, Song Zhou, Dongmei Liu, Xinhui Jiang, Zhengwei Zhang, Siqiao Li.  (2024)  Smartphone-assisted fluorescent sensor for the visualization and quantitative detection of doxycycline and L-arginine.  FOOD CHEMISTRY,      [PMID:39024874] [10.1016/j.foodchem.2024.140365]

28. Yan Tang, Xiaohan Xia, Zhenqi Zhu, Xun Zhang, Bin Yang.  (2024)  Terahertz spectroscopic study of the dehydration process and hydrogen bonding network of DL-glutamic acid and its monohydrate.  JOURNAL OF MOLECULAR STRUCTURE,      [PMID:] [10.1016/j.molstruc.2024.138610]

29. Tian Zhang, Zhiwen Gan, Shujun Zhen, Yongmei Hu, Xiaoli Hu.  (2022)  Monitoring of glutathione using ratiometric fluorescent sensor based on MnO2 nanosheets simultaneously tuning the fluorescence of Rhodamine 6G and thiamine hydrochloride.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:35114634] [10.1016/j.saa.2022.120942]

30. Fu Xiaori, Gu Xiaogang, Lu Shuguang, Miao Zhouwei, Xu Minhui, Zhang Xiang, Danish Muhammad, Cui Hang, Farooq Usman, Qiu Zhaofu, Sui Qian.  (2015)  Enhanced degradation of benzene by percarbonate activated with Fe(II)-glutamate complex.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  23  (7): (6758-6766).  [PMID:26662563] [10.1007/s11356-015-5908-2]