Doramectin - ≥98% , CAS No.117704-25-3

CAS: 117704-25-3 Cat. No.: D127678 Peso molecular: 899.11 Número EC: 601-490-4 PubChem CID: 9832750
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
Doramectina | Doramectine [INN-French] | Doramectina [INN-Spanish] | Doramectin | Doramectine | Doramectinum | Dectomax | Doramectinum [INN-Latin]
Storage
Store at 2-8°C,Protected from light
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
200mg
D127678-200mg
4
21,90US$
1g
D127678-1g
2
51,90US$
5g
D127678-5g
1
128,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Protected from light Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model.

Specifications

Sinónimos
Doramectina | Doramectine [INN-French] | Doramectina [INN-Spanish] | Doramectin | Doramectine | Doramectinum | Dectomax | Doramectinum [INN-Latin]
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
Doramectin is a derivative of ivermectin. It is thought to work like other macrocyclic lactones by opening glutamate-gated chloride channels in the nerve cells, causing paralysis.
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Protected from light
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥98%
Nombres e identificadores
Pubchem Sid504764928
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504764928
Sonrisas canónicasCC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)O)OC)OC)C)OC7(C4)C=CC(C(O7)C8CCCCC8)C)O
IUPAC Name(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-cyclohexyl-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
InChIKeyQLFZZSKTJWDQOS-YDBLARSUSA-N
INCHI1S/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,29,31-33,35-47,51-52,54H,9-11,14-15,18,22-26H2,1-8H3/b13-12+,28-17+,34-16+/t27-,29-,31-,32-,35+,36-,37-,38-,39-,40-,41-,42+,43-,44-,45-,46-,47+,49+,50+/m0/s1
Isómeros SMILES C[C@H]1/C=C/C=C/2\CO[C@H]3[C@@]2([C@@H](C=C([C@H]3O)C)C(=O)O[C@H]4C[C@@H](C/C=C(/[C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)OC)\C)O[C@]7(C4)C=C[C@@H]([C@H](O7)C8CCCCC8)C)O
WGK Alemania 3
PubChem CID 9832750
Peso molecular 899.11

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClaseMacrolides and analogues
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentMacrolides and analogues
Alternative Parents Disaccharides  O-glycosyl compounds  Ketals  Oxanes  Pyrans  Tertiary alcohols  Tetrahydrofurans  Secondary alcohols  Lactones  Carboxylic acid esters  Oxacyclic compounds  Monocarboxylic acids and derivatives  Dialkyl ethers  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic heteropolycyclic compounds
Substituents Macrolide - Disaccharide - Glycosyl compound - O-glycosyl compound - Ketal - Oxane - Pyran - Tetrahydrofuran - Tertiary alcohol - Secondary alcohol - Carboxylic acid ester - Lactone - Acetal - Carboxylic acid derivative - Organoheterocyclic compound - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Oxacycle - Organic oxygen compound - Alcohol - Organic oxide - Organooxygen compound - Hydrocarbon derivative - Carbonyl group - Aliphatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as macrolides and analogues. These are organic compounds containing a lactone ring of at least twelve members.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
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Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
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Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
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Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeFechaArticulo
E1504009Certificate of AnalysisJun 15, 2026 D127678
G2429426Certificate of AnalysisMay 19, 2026 D127678
G2429429Certificate of AnalysisMay 19, 2026 D127678
G2429431Certificate of AnalysisMay 19, 2026 D127678
G2429434Certificate of AnalysisMay 19, 2026 D127678
Propiedades químicas y físicas
SolubilidadSoluble in water (partly), chloroform, and methanol., Soluble in water (partly), chloroform, and methanol.
SensibilidadHeat sensitive; light sensitive
Peso molecular899.100 g/mol
XLogP34.500
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count14
Rotatable Bond Count7
Exact Mass898.508 Da
Monoisotopic Mass898.508 Da
Topological Polar Surface Area170.000 Ų
Heavy Atom Count64
Formal Charge0
Complexity1790.000
Isotope Atom Count0
Defined Atom Stereocenter Count19
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count3
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds3
Covalently-Bonded Unit Count1
Citations of This Product
Referencias
1. Gu Yu-Xin, Yan Tian-Ci, Yue Zi-Xuan, Li Min-Hui, Zheng Hui, Wang Shu-Ling, Cao Jun.  (2022)  Dispersive Micro-solid-Phase Extraction of Acaricides from Fruit Juice and Functional Food Using Cucurbituril as Sorbent.  Food Analytical Methods,  15  (5): (1356-1367).  [PMID:] [10.1007/s12161-021-02209-8]
2. Wang Yuanshan, Gong Meihua, Wang Xianlin, Peng Xiaolun, Wang Yuwei, Guan Jiahui, Cheng Dongyuan, Weng Chunyue, Zheng Yuguo.  (2020)  Efficient degradation of ivermectin by newly isolated Aeromonas taiwanensis ZJB-18,044.  BIODEGRADATION,  31  (4): (275-288).  [PMID:32936376] [10.1007/s10532-020-09909-8]
3. Guanqiong Na, Xiaofei Hu, Yaning Sun, Sharon Kwee, Guangxu Xing, Yunrui Xing, Gaiping Zhang.  (2020)  A highly sensitive monoclonal antibody−based paper sensor for simultaneously detecting valnemulin and tiamulin in porcine liver.  JOURNAL OF FOOD SCIENCE,  85  (6): (1681-1688).  [PMID:32418205] [10.1111/1750-3841.15136]
4. Jiawen Ji, Siyue Zhu, Xinping Hu, Jianhui Zhu, Sen Pang, Yongqiang Ma, Xuefeng Li.  (2025)  Enhanced residual risk of abamectin induced by 6PPD: in water, soil, and vegetables.  Environmental Science-Processes & Impacts,      [PMID:40099488] [10.1039/D5EM00053J]
5. Yi Li, Long Gong, Jing Wu, Wesley Hung, Mei Zhen, Shangbang Gao.  (2025)  UBR-1 deficiency leads to ivermectin resistance in Caenorhabditis elegans.  eLife,      [PMID:40167441] [10.7554/eLife.103718]
6. Mengfan Hu, Huan Xu, Yihong Li, Ziru Lian.  (2025)  ZnO-based molecularly imprinted fluorescence nanoprobe for selective recognition and ratiometric quantification of pectenotoxin2 in seawater.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.115627]
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