DPH - ≥98% , CAS No.484049-04-9

CAS: 484049-04-9 Cat. No.: D126816 Peso molecular: 336.32
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
DTXSID30349772 | 5-[3-(4-fluorophenyl)-1-phenyl-4-pyrazolyl]imidazolidine-2,4-dione | SMR000041163 | 5-[3-(4-fluorophenyl)-1-phenyl-1h-pyrazol-4-yl]-2,4-imidazolidinedione | 5-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)imidazolidine-2,4-dione | 5-[3-(4-
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
10mg
D126816-10mg
3
181,90US$
50mg
D126816-50mg
3
796,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 9 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

DPH
DPH may be used in c-Abl tyrosine kinase-mediated cell signaling studies.

Specifications

Sinónimos
DTXSID30349772 | 5-[3-(4-fluorophenyl)-1-phenyl-4-pyrazolyl]imidazolidine-2, 4-dione | SMR000041163 | 5-[3-(4-fluorophenyl)-1-phenyl-1h-pyrazol-4-yl]-2, 4-imidazolidinedione | 5-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)imidazolidine-2, 4-dione | 5-[3-(4-
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
DPH binds and changes the conformation of the c-Abl tyrosine kinase myristoyl-binding site. Shows potent enzymatic and cellular activity that stimulates c-Abl activation. DPH is a potent cell-permeable c-Abl activator. DPH binds to the myristoyl binding s
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
ACTIVATOR
Pureza
≥98%
Nombres e identificadores
Pubchem Sid504759797
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504759797
Sonrisas canónicasC1=CC=C(C=C1)N2C=C(C(=N2)C3=CC=C(C=C3)F)C4C(=O)NC(=O)N4
IUPAC Name5-[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]imidazolidine-2,4-dione
InChIKeyMPQWYPLPWGUMJE-UHFFFAOYSA-N
INCHI1S/C18H13FN4O2/c19-12-8-6-11(7-9-12)15-14(16-17(24)21-18(25)20-16)10-23(22-15)13-4-2-1-3-5-13/h1-10,16H,(H2,20,21,24,25)
Isómeros SMILES C1=CC=C(C=C1)N2C=C(C(=N2)C3=CC=C(C=C3)F)C4C(=O)NC(=O)N4
WGK Alemania 3
Peso molecular 336.32
Reaxy-Rn 21813460
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21813460&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseAzoles
SubclassPyrazoles
Intermediate Tree Nodes Not available
Direct ParentPhenylpyrazoles
Alternative Parents Alpha amino acids and derivatives  5-monosubstituted hydantoins  N-acyl ureas  Fluorobenzenes  Aryl fluorides  Heteroaromatic compounds  Dicarboximides  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organofluorides  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Hydantoin - Phenylpyrazole - Alpha-amino acid or derivatives - 5-monosubstituted hydantoin - Fluorobenzene - Halobenzene - Ureide - N-acyl urea - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Imidazolidinone - Dicarboximide - Heteroaromatic compound - Imidazolidine - Carbonic acid derivative - Urea - Azacycle - Carboxylic acid derivative - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Organic nitrogen compound - Carbonyl group - Organic oxide - Organopnictogen compound - Organohalogen compound - Organofluoride - Organonitrogen compound - Aromatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as phenylpyrazoles. These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ddn Putative uncharacterized protein (49 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeFechaArticulo
K2219647Certificate of AnalysisJun 09, 2026 D126816
K2219648Certificate of AnalysisJun 09, 2026 D126816
Propiedades químicas y físicas
SolubilidadDMSO
Peso molecular336.300 g/mol
XLogP32.400
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass336.102 Da
Monoisotopic Mass336.102 Da
Topological Polar Surface Area76.000 Ų
Heavy Atom Count25
Formal Charge0
Complexity517.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Yang Xiaoling, Zhao Shunan, Deng Yong, Xu Weidong, Wang Zonghan, Wang Wenjun, Lv Ruiling, Liu Donghong.  (2023)  Antibacterial activity and mechanisms of α-terpineol against foodborne pathogenic bacteria.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,      [PMID:37682300] [10.1007/s00253-023-12737-4]
2. Xinyue Ye, Jian Wang, Pengfei Xu, Xiaoqian Yang, Qixue Shi, Genyan Liu, Zhaoshi Bai, Changlin Zhou, Lingman Ma.  (2023)  Peptide MSI-1 inhibited MCR-1 and regulated outer membrane vesicles to combat immune evasion of Escherichia coli.  Microbial Biotechnology,      [PMID:37329166] [10.1111/1751-7915.14297]
3. Yang Gao, Ya Sun, Guangli Liao, Hailong Zhang, Qingzhi Long.  (2021)  DSPE-PEG polymers for improving pulmonary absorption of poorly absorbed macromolecules in rats and relative mechanism.  DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY,      [PMID:33502913] [10.1080/03639045.2021.1879837]
4. Guosong Xin, Miao Yu, Yang Hu, Shiyong Gao, Zheng Qi, Yuan Sun, Wenjing Yu, Jiaxin He, Yubin Ji.  (2020)  Effect of lycorine on the structure and function of hepatoma cell membrane in vitro and in vivo.  BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT,      [PMID:] [10.1080/13102818.2020.1719019]
5. Rui Wang, Zhaoyue Dong, Xiaolong Zhang, Jingxin Mao, Fancheng Meng, Xiaozhong Lan, Zhihua Liao, Min Chen.  (2019)  Evaluation of the Liver Toxicity of Pterocephalus hookeri Extract via Triggering Necrosis.  Toxins,  11  (3): (142).  [PMID:30832306] [10.3390/toxins11030142]
6. Ou Yun, Zhi-Wei Liu, Xin-An Zeng, Zhong Han.  (2016)  Salmonella typhimurium resistance on pulsed electric fields associated with membrane fluidity and gene regulation.  Innovative Food Science & Emerging Technologies,      [PMID:] [10.1016/j.ifset.2016.06.013]
7. Hong Zhuang, Xiaoliang Zhang, Sijia Wu, Chen Mao, Yaxi Dai, Pang Yong, Xiaodi Niu.  (2024)  Study transport of hesperidin based on the DPPC lipid model and the BSA transport model.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:38513316] [10.1016/j.saa.2024.124172]
8. Sijia Wu, Ping Jiang, Xiaoliang Zhang, Chen Mao, Yaxi Dai, Hong Zhuang, Yong Pang.  (2024)  Understanding the Transepithelial Transport and Transbilayer Diffusion of the Antihypertensive Peptide Asn-Cys-Trp: Insights from Caco-2 Cell Monolayers and the DPPC Model Membrane.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:38639269] [10.1021/acs.jafc.4c00155]
9. Meng Jin, Ge Gao, Zeyu Liu, Xiao Meng, Haiyan Wei, Wenwen Chen, Hui Pan, Mengping Zhang, Qiang Jia, Cuijuan Wang.  (2025)  Rapid detection of diphenhydramine in children’s cosmetics using SERS-active gold hedgehog particles/MOF-801 deposited on cellulose nanofibrils films.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2025.138883]
Calculadoras de soluciones
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