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DRB18 - ≥98% , CAS No.D414435
Disponible para pedir
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Information
DRB18 DRB18 is a pan-GLUT (glucose transporters) inhibitor that inhibits growth and proliferation in several different cancer types with IC50 high nM range.
Targets
GLUT
In vitro
DRB18 inhibits growth and proliferation in about 90% of the 60 different cancer cell lines in 9 major cancer types. DRB18 treatment leads to significant changes in glucose-based metabolism in A549 lung cancer cells, including cell death via ER/oxidative stress and necrosis.
In vivo
DRB18 (10 mg/kg) treatment thrice a week significantly reduces growth in Xenograft A549 tumors.
Specifications
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
DRB18 is a pan-GLUT (glucose transporters) inhibitor that inhibits growth and proliferation in several different cancer types with IC50 high nM range.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥98%
Propiedades del producto
| ALogP | 5.767 |
|---|---|
| Recuento HBD | 4 |
| Enlace rotable | 6 |
Nombres e identificadores
| Sonrisas canónicas | CC1=CC=C(CNC2=C(NCC3=CC(=C(C)C=C3)O)C=C(Cl)C=C2)C=C1O |
|---|---|
| Peso molecular | 382.88 |
| Reaxy-Rn | 36374407 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=36374407&ln= |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | Solubility (25°C) In vitro DMSO: 76 mg/mL (198.49 mM); Ethanol: 76 mg/mL (198.49 mM); Water: Insoluble; |
|---|---|
| DMSO (mg/ml) Solubilidad máxima | 76 |
| DMSO (mM) Solubilidad máxima | 198.495612202257 |
| Agua (mg/ml) Solubilidad máxima | ＜1 |
Calculadoras de soluciones
Reseñas
Reseñas de cliente
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