DSPE-PEG Carboxylic acid sodium - MW 2000 , CAS No.1403744-37-5

CAS: 1403744-37-5 Cat. No.: D646435 Número EC: 639-215-5

GRADE & PURITY MW 2000

Synonyms

1403744-37-5

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Carboxylic acids are readily soluble in polar solvents such as water and alcohols. DSPE-PEG(2000) carboxylic acid consists of a hydrophilic polyethylene glycol (PEG) chain of 2kDa.
DSPE-PEG(2000) carboxylic acid has been used:
· to covalently conjugate integrin α-2 (ITGA2) antibodies to the surface of the liposomes
· in the preparation of atosiban-conjugated liposomes
· to prepare dual complementary liposome

Specifications

Sinónimos

1403744-37-5

Especificaciones y pureza

MW 2000

Mecanismos bioquímicos y fisiológicos

DSPE-PEG Carboxylic acid sodium (MW 2000) is a PEG-lipid that can be used to form micelles as nanoparticles for drug delivery. DSPE-PEG Carboxylic acid sodium (MW 2000) increases the blood circulation time of liposomes.DSPE-PEG(2000) carboxylic acid incre

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Sonrisas canónicas: CC1=CC=C(C=C1)C(=C2C(N(C(=O)C2=O)C3=NN=C(C=C3)C)C4=CC=C(C=C4)OC5CCN(CC5)C)O.CC1=NC=C(C=C1)N2C(C(=C(C3=CC=C(C=C3)C(C)C)O)C(=O)C2=O)C4=CC=C(C=C4)C(C)C.CC1=NN=C(C=C1)N2C(C(=C(C3=CC=C(C=C3)C(C)C)O)C(=O)C2=O)C4=CC=C(C=C4)OCCN5CCOCC5.CC1=NN=C(C=C1)N2C(C(=C(C3=CC=C(C=C3)N4CCOCC4)O)C(=O)C2=O)C5=CC=C(C=C5)OC.CC1=NN=C(C=C1)N2C(C(=C(C3=CC=C(C=C3)N(C)C)O)C(=O)C2=O)C4=CC=C(C=C4)OC(F)(F)F
• IUPAC Name: 4-[[4-(dimethylamino)phenyl]-hydroxymethylidene]-1-(6-methylpyridazin-3-yl)-5-[4-(trifluoromethoxy)phenyl]pyrrolidine-2,3-dione;4-[hydroxy-(4-methylphenyl)methylidene]-5-[4-(1-methylpiperidin-4-yl)oxyphenyl]-1-(6-methylpyridazin-3-yl)pyrrolidine-2,3-dione;4-[hydroxy-(4-morpholin-4-ylphenyl)methylidene]-5-(4-methoxyphenyl)-1-(6-methylpyridazin-3-yl)pyrrolidine-2,3-dione;4-[hydroxy-(4-propan-2-ylphenyl)methylidene]-1-(6-methylpyridazin-3-yl)-5-[4-(2-morpholin-4-ylethoxy)phenyl]pyrrolidine-2,3-dione;4-[hydroxy-(4-propan-2-ylphenyl)methylidene]-1-(6-methylpyridin-3-yl)-5-(4-propan-2-ylphenyl)pyrrolidine-2,3-dione
• InChIKey: NIXOVWUDDMBODS-UHFFFAOYSA-N
• INCHI: 1S/C31H34N4O5.C29H30N4O4.C29H30N2O3.C27H26N4O5.C25H21F3N4O4/c1-20(2)22-5-7-24(8-6-22)29(36)27-28(35(31(38)30(27)37)26-13-4-21(3)32-33-26)23-9-11-25(12-10-23)40-19-16-34-14-17-39-18-15-34;1-18-4-7-21(8-5-18)27(34)25-26(33(29(36)28(25)35)24-13-6-19(2)30-31-24)20-9-11-22(12-10-20)37-23-14-16-32(3)17-15-23;1-17(2)20-7-11-22(12-8-20)26-25(27(32)23-13-9-21(10-14-23)18(3)4)28(33)29(34)31(26)24-15-6-19(5)30-16-24;1-17-3-12-22(29-28-17)31-24(18-6-10-21(35-2)11-7-18)23(26(33)27(31)34)25(32)19-4-8-20(9-5-19)30-13-15-36-16-14-30;1-14-4-13-19(30-29-14)32-21(15-7-11-18(12-8-15)36-25(26,27)28)20(23(34)24(32)35)22(33)16-5-9-17(10-6-16)31(2)3/h4-13,20,28,36H,14-19H2,1-3H3;4-13,23,26,34H,14-17H2,1-3H3;6-18,26,32H,1-5H3;3-12,24,32H,13-16H2,1-2H3;4-13,21,33H,1-3H3
• Isómeros SMILES: CC1=CC=C(C=C1)C(=C2C(N(C(=O)C2=O)C3=NN=C(C=C3)C)C4=CC=C(C=C4)OC5CCN(CC5)C)O.CC1=NC=C(C=C1)N2C(C(=C(C3=CC=C(C=C3)C(C)C)O)C(=O)C2=O)C4=CC=C(C=C4)C(C)C.CC1=NN=C(C=C1)N2C(C(=C(C3=CC=C(C=C3)C(C)C)O)C(=O)C2=O)C4=CC=C(C=C4)OCCN5CCOCC5.CC1=NN=C(C=C1)N2C(C(=C(C3=CC=C(C=C3)N4CCOCC4)O)C(=O)C2=O)C5=CC=C(C=C5)OC.CC1=NN=C(C=C1)N2C(C(=C(C3=CC=C(C=C3)N(C)C)O)C(=O)C2=O)C4=CC=C(C=C4)OC(F)(F)F
• CAS alternativo: 8022-37-5

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Oxazinanes
      • Subclass Morpholines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Oxazinanes
• Subclass: Morpholines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylmorpholines
• Alternative Parents: Phenylpyrrolidines Monocyclic monoterpenoids Aromatic monoterpenoids Phenylpropanes Cumenes Phenoxy compounds Methoxybenzenes Dialkylarylamines Anisoles Aniline and substituted anilines Toluenes Methylpyridines Alkyl aryl ethers Pyrrolidine-3-ones Pyrrolidine-2-ones Pyridazines and derivatives Piperidines Imidolactams Vinylogous acids Tertiary carboxylic acid amides Pyrroles Heteroaromatic compounds Trihalomethanes Trialkylamines Lactams Cyclic ketones Amino acids and derivatives Oxacyclic compounds Enols Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides
• Molecular Framework: Not available
• Substituents: Phenylmorpholine - 2-phenylpyrrolidine - Monoterpenoid - Monocyclic monoterpenoid - Aromatic monoterpenoid - P-cymene - Phenylpropane - Cumene - Phenoxy compound - Methoxybenzene - Aniline or substituted anilines - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Phenol ether - Anisole - Methylpyridine - Toluene - Alkyl aryl ether - Imidolactam - Benzenoid - 3-pyrrolidone - 2-pyrrolidone - Pyrrolidone - Pyridine - Pyridazine - Piperidine - Monocyclic benzene moiety - Heteroaromatic compound - Vinylogous acid - Tertiary carboxylic acid amide - Pyrrolidine - Pyrrole - Trihalomethane - Cyclic ketone - Tertiary aliphatic amine - Tertiary amine - Lactam - Ketone - Carboxamide group - Amino acid or derivatives - Oxacycle - Azacycle - Ether - Enol - Dialkyl ether - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Halomethane - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Carbonyl group - Amine - Alkyl halide - Alkyl fluoride - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as phenylmorpholines. These are aromatic compounds containing a morpholine ring and a benzene ring linked to each other through a CC or a CN bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: THF : 50 mg/mL (Need ultrasonic)
• Sensibilidad: Moisture sensitive

Referencias

1. Ying Xu, Yang Xu, Fating Chen, Encheng Li, Chunxiu Hu, Xinyu Liu, Xianzhe Shi, Guowang Xu.  (2025)  Dual Aptamers Functionalized Biomimetic Magnetic Nanomaterials for High-Efficient Capture of Circulating Tumor Cells.  ACS Applied Bio Materials,      [PMID:40754978] [10.1021/acsabm.5c01173]

2. Xinru Chen, Xiaoyan Wang, Jin Li.  (2026)  Metabolizable van der Waals enhanced Raman scattering probes for CXCR4-targeted imaging guided cancer therapy in NIR-II window.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2026.174187]

3. Kunlin Wu, Zhiye Liu, Junquan Hu, Teng Li, Junhong Fan, Chunxiang Feng, Hanzhong Chen, Dong Li, Shang Huang.  (2026)  Engineered prostate-specific membrane antigen-targeted liposomal nanoplatform integrating near-infrared fluorescence, ultrasound, and magnetic resonance imaging for precision prostate cancer imaging.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2026.115935]