DSPE PEG Maleimide, DSPE-PEG-MAL - MW 2000 Da , CAS No.474922-22-0

CAS: 474922-22-0 Cat. No.: D163619 PubChem CID: 156594503

GRADE & PURITY MW 2000 Da

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

228,229

Descripción general

1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjμgated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjμgate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drμg delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drμgs. These materials can also be used for targeted drμg delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.

DSPE-PEG(2000) maleimide is suitable for conjugation with photon-sensitive cell penetrating peptides (psCPP) to prepare nanostructured lipid carrier. It is also suitable for non-covalently functionalizing oxidized multi-walled carbon nanotubes (O-MWCNs).

Specifications

Especificaciones y pureza

MW 2000 Da

Mecanismos bioquímicos y fisiológicos

DSPE-PEG(2000) maleimide is used to prepare conjugated polymer nanoparticles. It is suitable for its use in the synthesis of functional conjugates

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Sonrisas canónicas: CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)OCCOCCNC(=O)CCN1C(=O)C=CC1=O)OC(=O)CCCCCCCCCCCCCCCCC.N
• IUPAC Name: azane;[3-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxycarbonylamino]ethoxy-hydroxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate
• InChIKey: HMLYGTOVHVFLDS-UHFFFAOYSA-N
• INCHI: 1S/C53H96N3O14P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-51(60)67-45-47(70-52(61)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)46-69-71(63,64)68-42-39-55-53(62)66-44-43-65-41-38-54-48(57)37-40-56-49(58)35-36-50(56)59;/h35-36,47H,3-34,37-46H2,1-2H3,(H,54,57)(H,55,62)(H,63,64);1H3
• PubChem CID: 156594503

Propiedades químicas y físicas

• Solubilidad: Solubility: Soluble in chloroform and warm water
• Sensibilidad: Light & Moisture sensitive

Referencias

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4. Yuwen Song, Tingting Xu, Hao Li, Jing Liu, Shumin Cao, Yichen Yang, Nianlu Li, Peiwen Lv, Min Han, Haohan Sun, Guangfu Dang, Jianxin Li, Hao Sun, Tao Xin, Huitang Xia, CanWei Zhang.  (2025)  Delivery of Itgb1-siRNA by triptolide-modified and anti-Flt1 peptide-guided ionizable cationic LNPs for targeted therapy of corneal neovascularization.  JOURNAL OF CONTROLLED RELEASE,      [PMID:40324532] [10.1016/j.jconrel.2025.113811]

5. Yuxiang Gao, Rong Ma, Lijun Zhu, Zhong Du, Jiabao Xiong, Chi Zhang, Xueliang Zhang, Cailing Ma, Nuernisha Alifu.  (2025)  Theranostic Nanoprobes Assisted NIR-II Fluorescence Imaging for Efficient Angiography and Tumor Therapy.  ACS Omega,      [PMID:40454026] [10.1021/acsomega.5c01553]

6. Chao Fang, Daihan Xie, Fanlei Kong, Xin Yu, Jingting Yin, Yu Huo, Chunxia Su.  (2026)  Lipid-Engineered Small-Sized Metal-Organic Frameworks for Targeted Delivery of Anlotinib in Lung Cancer Treatment.  International Journal of Nanomedicine,      [PMID:] [10.2147/IJN.S566873]