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DX600 TFA - ≥99% , CAS No.D414451
Disponible para pedir
GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Information
DX600 DX600 is a specific inhibitor of angiotensin-converting enzyme 2 (ACE2) that does not cross-react with ACE.
Targets
ACE2
In vitro
DX600 is an ACE2 specific inhibitor that does not cross-react with ACE. Three human cell lines (Calu-3, Caco-2, Huh-7) are evaluated for the cell surface expression of ACE2 by flow cytometry and Western blot. Subsequently, whole cell lysates, cell culture supernatant, and live cells are evaluated in the assay. Calu-3 has elevated levels of ACE2 compared to Caco-2 or Huh-7. Calu-3 also demonstrates elevated ACE2 enzymatic activity in all three sources and can be inhibited by DX600.
In vivo
Mouse ACE2-driven Ang-(1-7) formation from Ang II is blocked by MLN-4760 but not by either linear or cyclic DX600. DX600 only blocks human ACE2 activity.
Cell Research(from reference)
Cell lines：Three human cell lines (Calu-3, Caco-2, Huh-7)
Concentrations：10 μM
Incubation Time：1 h
Specifications
Especificaciones y pureza
≥99%
Mecanismos bioquímicos y fisiológicos
DX600 is a specific inhibitor of angiotensin-converting enzyme 2 (ACE2) that does not cross-react with ACE.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥99%
Nombres e identificadores
| Peso molecular | 3074.32 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 G2313477 | Certificate of Analysis | Apr 07, 2026 | D414451 |
| G2313479 | Certificate of Analysis | Apr 07, 2026 | D414451 |
| G2313487 | Certificate of Analysis | Apr 07, 2026 | D414451 |
| G2313488 | Certificate of Analysis | Apr 07, 2026 | D414451 |
| G2313493 | Certificate of Analysis | Apr 07, 2026 | D414451 |
| G2313514 | Certificate of Analysis | Apr 07, 2026 | D414451 |
Propiedades químicas y físicas
| Solubilidad | Solubility (25°C) In vitro Water: 100 mg/mL (32.52 mM); |
|---|
Calculadoras de soluciones
Reseñas
Reseñas de cliente
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