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E-3810 - Moligand™, ≥98% , Fibroblast growth factor receptor 2 inhibitor, CAS No.1058137-23-7, Fibroblast growth factor receptor 2 inhibitor

CAS: 1058137-23-7 Cat. No.: E127640 Fórmula: C26H25N3O4 Peso molecular: 443.49
COA
E-3810 - Moligand™, ≥98% CAS No(1058137-23-7) by Aladdin Scientific
Disponible para pedir
CALIDAD & PUREZA Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
1,13-dimethyl-10-(3-methyl-2-butenyl)-(1R,9R,13R)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Pentazocine) | LUCITANIB [WHO-DD] | Pentobarbitone (VAN) | 6-((7-((1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yl)oxy)-N-methyl-1-naphthamide | AMY
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Talla
USA
Alemania (EU)*
Precio
Cantidad
1mg
E127640-1mg
3 Disponible
—

69,90US$

104,90US$
Guardar 35,00 US$ (33.37%)
5mg
E127640-5mg
3 Disponible
—

89,90US$

134,90US$
Guardar 45,00 US$ (33.36%)
10mg
E127640-10mg
2 Disponible
—

116,90US$

175,90US$
Guardar 59,00 US$ (33.54%)
25mg
E127640-25mg
2 Disponible
—

151,90US$

227,90US$
Guardar 76,00 US$ (33.35%)
50mg
E127640-50mg
2 Disponible
—

256,90US$

385,90US$
Guardar 129,00 US$ (33.43%)
100mg
E127640-100mg
Fabricado bajo pedido · 8–12 semanas

436,90US$

655,90US$
Guardar 219,00 US$ (33.39%)
Enter a quantity for the sizes you want to add.
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SDS
Safety data
COA
Certificate
DS
Ficha técnica
SP
Hoja de especificaciones
Especificaciones Propiedades del producto Nombres e identificadores Datos avanzados Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas

Especificaciones

Sinónimos
1,13-dimethyl-10-(3-methyl-2-butenyl)-(1R,9R,13R)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Pentazocine) | LUCITANIB [WHO-DD] | Pentobarbitone (VAN) | 6-((7-((1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yl)oxy)-N-methyl-1-naphthamide | AMY
Especificaciones y pureza
Moligand™, ≥98%
Mecanismos bioquímicos y fisiológicos

E-3810, a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. VEGFR/FGFR dual kinase inhibitor E-3810 inhibits VEGFR-1, -2

Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Mecanismo de acción
Fibroblast growth factor receptor 2 inhibitor
Pureza
≥98%
Propiedades del producto
ALogP
3.6
Nombres e identificadores
Pubchem Sid
504769941
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/504769941
Sonrisas canónicas
CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC
IUPAC Name
6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-methylnaphthalene-1-carboxamide
InChIKey
CUDVHEFYRIWYQD-UHFFFAOYSA-N
INCHI
1S/C26H25N3O4/c1-28-25(30)19-5-3-4-16-12-17(6-7-18(16)19)33-22-8-11-29-21-14-24(23(31-2)13-20(21)22)32-15-26(27)9-10-26/h3-8,11-14H,9-10,15,27H2,1-2H3,(H,28,30)
Isómeros SMILES
CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC
Peso molecular
443.49
Reaxy-Rn
18478470
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18478470&ln=

Datos avanzados

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseNaphthalenes
SubclassNaphthalenecarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentNaphthalenecarboxamides
Alternative Parents Diarylethers  Quinolines and derivatives  Anisoles  Alkyl aryl ethers  Pyridines and derivatives  Heteroaromatic compounds  Secondary carboxylic acid amides  Amino acids and derivatives  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 1-naphthalenecarboxamide - Diaryl ether - Quinoline - Anisole - Alkyl aryl ether - Pyridine - Heteroaromatic compound - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Ether - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Primary aliphatic amine - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Organonitrogen compound - Organooxygen compound - Primary amine - Organopnictogen compound - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as naphthalenecarboxamides. These are compounds containing a naphthalene moiety, which bears a carboxylic acid amide group at one or more positions. Naphthalene is a bicyclic compound that is made up of two fused benzene rings.
External Descriptors aromatic ether - quinolines - primary amino compound - cyclopropanes - naphthalenecarboxamide
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
DDR1 Tchem Epithelial discoidin domain-containing receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RET Tclin Proto-oncogene tyrosine-protein kinase receptor Ret (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FLT4 Tclin Vascular endothelial growth factor receptor 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FGFR1 Tclin Fibroblast growth factor receptor 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDGFRA Tclin Platelet-derived growth factor receptor alpha (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDGFRB Tclin Platelet-derived growth factor receptor beta (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FLT1 Tclin Vascular endothelial growth factor receptor 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDR Tclin Vascular endothelial growth factor receptor 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KIT Tclin Mast/stem cell growth factor receptor Kit (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeFechaArticulo
L2420505L2420505Certificate of AnalysisSep 21, 2026 E127640
B2603038B2603038Certificate of AnalysisFeb 25, 2026 E127640
L2117112L2117112Certificate of AnalysisJul 15, 2025 E127640
L2117113L2117113Certificate of AnalysisJul 15, 2025 E127640
L2117128L2117128Certificate of AnalysisJul 15, 2025 E127640
L2117319L2117319Certificate of AnalysisJul 15, 2025 E127640
L2117320L2117320Certificate of AnalysisJul 15, 2025 E127640
L2117321L2117321Certificate of AnalysisJul 15, 2025 E127640
Propiedades químicas y físicas
SolubilidadDMSO
Peso molecular443.500 g/mol
XLogP33.600
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass443.185 Da
Monoisotopic Mass443.185 Da
Topological Polar Surface Area95.700 Ų
Heavy Atom Count33
Formal Charge0
Complexity686.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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