(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate - ≥83% , CAS No.1191901-33-3

CAS: 1191901-33-3 Cat. No.: E486554 Peso molecular: 267.28

GRADE & PURITY ≥83%

Synonyms

(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate | SCHEMBL1300090 | BP-22417 | 1191901-33-3 | TCO-NHS | Carbonic acid, (4E)-4-cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl ester | Tco-N-hydroxysuccinimidyl carbonate | TCO-NHS ester | 2249928-24-1 | OUGQJ

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

227,228,229

Descripción general

Description

Succinimidyl carbonate/NHS functionalized cyclooctene derivative for incorporation of the cyclooctene moiety into amine containing compounds or biomolecules. Cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1,2,4,5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate may be used in the synthesis of vancomycin-TCO that can bind to the cell wall of gram-positive bacteria, which can subsequently react with tetrazine (Tz) decorated magneto-fluorescent nanoparticles orthogonally. This bioorthogonal labeling method is useful for the detection of gram-positive bacteria.

Specifications

Sinónimos

(E)-Cyclooct-4-enyl 2, 5-dioxo-1-pyrrolidinyl carbonate | SCHEMBL1300090 | BP-22417 | 1191901-33-3 | TCO-NHS | Carbonic acid, (4E)-4-cycloocten-1-yl 2, 5-dioxo-1-pyrrolidinyl ester | Tco-N-hydroxysuccinimidyl carbonate | TCO-NHS ester | 2249928-24-1 | OUGQJ

Especificaciones y pureza

≥83%

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥83%

Nombres e identificadores

• Pubchem Sid: 488201927
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488201927
• Sonrisas canónicas: C1CC=CCCC(C1)OC(=O)ON2C(=O)CCC2=O
• IUPAC Name: [(4E)-cyclooct-4-en-1-yl] (2,5-dioxopyrrolidin-1-yl) carbonate
• InChIKey: OUGQJOKGFAIFAQ-OWOJBTEDSA-N
• INCHI: 1S/C13H17NO5/c15-11-8-9-12(16)14(11)19-13(17)18-10-6-4-2-1-3-5-7-10/h1-2,10H,3-9H2/b2-1+
• Isómeros SMILES: C1C/C=C/CCC(C1)OC(=O)ON2C(=O)CCC2=O
• Peso molecular: 267.28
• Reaxy-Rn: 27594158
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27594158&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrrolidine-2-ones
• Alternative Parents: Dicarboximides Organic carbonic acids and derivatives Lactams Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: 2-pyrrolidone - Dicarboximide - Carbonic acid derivative - Lactam - Azacycle - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Sensibilidad: Moisture sensitive；Light sensitive；Heat sensitive