🌎 Ship to: United States
Toggle Nav
Cart
Buscar
Envío en el mismo día para todos los artículos en stock.
Búsqueda avanzada
Pedido rápido SDS CoA
Menú
Cuenta
Configuración
྾
224,000+ productos de investigación · Triple ISO certified · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items

EB 47, PARP-1 inhibitor - ≥98% , CAS No.1190332-25-2

CAS: 1190332-25-2 Cat. No.: E275357 Peso molecular: 610.4 PubChem CID: 124080891
COA
EB 47, PARP-1 inhibitor - ≥98% CAS No(1190332-25-2) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
2-[4-[(2R,3R,4S,5S)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolane-2-carbonyl]piperazin-1-yl]-N-(1-oxo-2,3-dihydroisoindol-4-yl)acetamidedihydrochloride
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5mg
E275357-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

265,90US$

398,90US$
Guardar 133,00 US$ (33.34%)
10mg
E275357-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

476,90US$

715,90US$
Guardar 239,00 US$ (33.38%)
25mg
E275357-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

1.043,90US$

1.565,90US$
Guardar 522,00 US$ (33.34%)
50mg
E275357-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

1.877,90US$

2.816,90US$
Guardar 939,00 US$ (33.33%)
100mg
E275357-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

3.379,90US$

5.069,90US$
Guardar 1.690,00 US$ (33.33%)
Enter a quantity for the sizes you want to add.
Bulk / Custom
♡ Lista de deseos ⇅ Añadir para comparar ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Descripción general Specifications Nombres e identificadores Documentation Advanced Data Estructura 3D Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Product description

EB-47 dihydrochloride, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM. EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.

Specifications

Sinónimos
2-[4-[(2R, 3R, 4S, 5S)-5-(6-Aminopurin-9-yl)-3, 4-dihydroxyoxolane-2-carbonyl]piperazin-1-yl]-N-(1-oxo-2, 3-dihydroisoindol-4-yl)acetamidedihydrochloride
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
Potent\xa0PARP-1 inhibitor\xa0(IC 50 = 45 nM). Can be used in the methods to treat asthma. Reduces infarct volume in both a rat transient middle cerebral arterial occlusion model and a cardiac reperfusion model.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Nota
Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasC1CN(CCN1CC(=O)NC2=CC=CC3=C2CNC3=O)C(=O)C4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O.Cl.Cl
IUPAC Name2-[4-[(2S,3R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolane-2-carbonyl]piperazin-1-yl]-N-(1-oxo-2,3-dihydroisoindol-4-yl)acetamide;dihydrochloride
InChIKeyVVMQSDIMNDTMII-LLGQWWOSSA-N
INCHI1S/C24H27N9O6.2ClH/c25-20-16-21(28-10-27-20)33(11-29-16)24-18(36)17(35)19(39-24)23(38)32-6-4-31(5-7-32)9-15(34)30-14-3-1-2-12-13(14)8-26-22(12)37;;/h1-3,10-11,17-19,24,35-36H,4-9H2,(H,26,37)(H,30,34)(H2,25,27,28);2*1H/t17-,18?,19+,24-;;/m1../s1
PubChem CID 124080891
Peso molecular 610.4

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadSoluble in water to 5 mM and in DMSO to 50 mM
SensibilidadMoisture sensitive
Calculadoras de soluciones
Reseñas

Reseñas de cliente

We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.

Privacy Policy Terms of Use Cookie Policy Terms and Conditions of Sale Sales Policy
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.