Eicosa-11Z,14Z-dienoic Acid - ≥98% , CAS No.2091-39-6

CAS: 2091-39-6 Cat. No.: E334903 Peso molecular: 308.50 Número EC: 680-553-8

GRADE & PURITY ≥98%

Synonyms

11C 14C-Eicosadienoic Acid | eicosa-11z,14z-dienoic acid | Eicosadienoic acid | C20:2n-6,9 | 11, 14-icosadienoic acid | 11(Z),14(Z)-Eicosadienoic Acid | (11E,14E)-icosa-11,14-dienoic acid | 11,14-Eicosadienoicacid | 11,14-Eicosadienoic acid | SCHEMBL27805

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Eicosa-11Z,14Z-dienoic acid is a polyunsaturated lipid analog of arachidonic acid. It has been shown to inhibit PP2 (calcineurin), a protein phosphatase which activates immune system T cells, to some extent in the absence of calmodulin.

Specifications

Sinónimos

11C 14C-Eicosadienoic Acid | eicosa-11z, 14z-dienoic acid | Eicosadienoic acid | C20:2n-6, 9 | 11, 14-icosadienoic acid | 11(Z), 14(Z)-Eicosadienoic Acid | (11E, 14E)-icosa-11, 14-dienoic acid | 11, 14-Eicosadienoicacid | 11, 14-Eicosadienoic acid | SCHEMBL27805

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Propiedades del producto

• Datos Ki: binding of [3H]-LTB4 to neutrophil membranes: Ki= 3 μM (pig)

Nombres e identificadores

• Pubchem Sid: 488195271
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488195271
• Sonrisas canónicas: CCCCCC=CCC=CCCCCCCCCCC(=O)O
• IUPAC Name: (11E,14E)-icosa-11,14-dienoic acid
• InChIKey: XSXIVVZCUAHUJO-AVQMFFATSA-N
• INCHI: 1S/C20H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10H,2-5,8,11-19H2,1H3,(H,21,22)/b7-6+,10-9+
• Isómeros SMILES: CCCCC/C=C/C/C=C/CCCCCCCCCC(=O)O
• WGK Alemania: 3
• Peso molecular: 308.50
• Reaxy-Rn: 1727825
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1727825&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Fatty Acyls
      • Subclass Fatty acids and conjugates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Fatty Acyls
• Subclass: Fatty acids and conjugates
• Intermediate Tree Nodes: Not available
• Direct Parent: Long-chain fatty acids
• Alternative Parents: Unsaturated fatty acids Straight chain fatty acids Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Long-chain fatty acid - Unsaturated fatty acid - Straight chain fatty acid - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as long-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
• External Descriptors: Unsaturated fatty acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in ethanol (~100 mg/ml), DMSO (~100 mg/ml), and DMF (~100 mg/ml). Insoluble in water.
• Sensibilidad: Air sensitive；Light sensitive
• Índice de refracción: n20D1.48
• Punto de ebullición (°C): 198° C at 0.08 mmHg
• Peso molecular: 308.500 g/mol
• XLogP3: 7.900
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 16
• Exact Mass: 308.272 Da
• Monoisotopic Mass: 308.272 Da
• Topological Polar Surface Area: 37.300 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 292.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 2
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 2
• Covalently-Bonded Unit Count: 1

Referencias

1. Jie Cheng, Yuling Li, Yunjun Wang, Jing Zhang, Tuanqi Sun, Li Zhang, Yinlong Guo.  (2022)  Quaterization Derivatization with Bis(Pyridine) Iodine Tetrafluoroboride: High-Sensitivity Mass Spectrometric Analysis of Unsaturated Fatty Acids in Human Thyroid Tissues.  ANALYTICAL CHEMISTRY,      [PMID:35916214] [10.1021/acs.analchem.2c01519]