10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Elacridar (GF120918; GW0918) is a P-glycoprotein inhibitor and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. A prototypical BCRP (ABCG2) inhibitor.
A prototypical BCRP (ABCG2) and MDR-1 inhibitor which inhibits the Bcrp1-mediated transport. It increases the availablity of cytotoxic antitumor drugs. Allows the uptake of more anti-HIV drugs in the brain and CNS.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
This compound belongs to the class of organic compounds known as acridones. These are acridines containing a ketone group attached to the C9 carbon atom of the acridine moiety.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Jieyu Zhang, Yan Chen, Wenxiang Fan, Linnan Li, Yueming Ma, Zhengtao Wang, Rong Shi, Li Yang. (2023) Study on herb-herb interaction between active components of Plantago asiatica L. seed and Coptis chinensis Franch. rhizoma based on transporters using UHPLC-MS/MS. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:36773541][10.1016/j.jpba.2023.115234]
2.Qiurui Li, Hua Lin, Yanfen Niu, Yan Liu, Zhenyu Wang, Liudong Song, Lihui Gao, Ling Li. (2020) Mangiferin promotes intestinal elimination of uric acid by modulating intestinal transporters. EUROPEAN JOURNAL OF PHARMACOLOGY, [PMID:32827538][10.1016/j.ejphar.2020.173490]
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