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EN40 - ≥99% , CAS No.2094547-67-6
Disponible para pedir
GRADE & PURITY ≥99%
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC 50 value of 2 uM
In Vitro
EN40 (10-1000 μM; 48 hours) shows inhibitory effecton ALDH3A1 activity and impairs A549 cell survival. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: A549 cells Concentration: 10 μM; 100 μM; 1000 μM Incubation Time: 48 hours Result: Inhibited A549 cells survival.
In Vivo
EN40 (intraperitoneal injection; 50mg/kg; from 14 days; once per day) exerts strong anti-tumorigenic effects in established A549 tumor xenografts, shows good tolerability with no body weight loss in mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: SCID mice with A549 cells Dosage: 50 mg/kg Administration: Intraperitoneal injection; 50mg/kg; from 14 days; once per day Result: Had strong anti-tumorigenic effects in tumor xenografts.
Form:Oil
IC50& Target:IC50: 2 uM (ALDH3A1)
Specifications
Especificaciones y pureza
≥99%
Mecanismos bioquímicos y fisiológicos
EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC 50 value of 2 uM
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥99%
Nombres e identificadores
| Sonrisas canónicas | CC1=C(CN(CC1)C(=O)C=C)C2=CC=CO2 |
|---|---|
| IUPAC Name | 1-[5-(furan-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-1-yl]prop-2-en-1-one |
| InChIKey | UYNKILJNUUDFFJ-UHFFFAOYSA-N |
| INCHI | 1S/C13H15NO2/c1-3-13(15)14-7-6-10(2)11(9-14)12-5-4-8-16-12/h3-5,8H,1,6-7,9H2,2H3 |
| PubChem CID | 126824761 |
| Peso molecular | 217.26 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Estructura 3D
Modelo de Estructura Química Interactiva
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | DMSO : 5 mg/mL (23.01 mM; Need ultrasonic) Ethanol : 2 mg/mL (9.21 mM; Need ultrasonic) |
|---|
Calculadoras de soluciones
Reseñas
Reseñas de cliente
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