Enalaprilat-d5 Sodium Salt , CAS No.1356922-29-6

CAS: 1356922-29-6 Cat. No.: E334926 Peso molecular: 375.41 Número EC: 875-668-7 PubChem CID: 45039129

Synonyms

Enalaprilat-d5 Sodium Salt | J-006752 | DTXSID10661944 | sodium;(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-(2,3,4,5,6-pentadeuteriophenyl)propyl]amino]propanoyl]pyrrolidine-2-carboxylate | Enalaprilat D5 Sodium Salt | 1356922-29-6 | Enalaprilic Acid-d5 | Sodium (2

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Enalaprilat-d5 Sodium Salt is a labeled metabolite of Enalapril. Enalapril is a angiotensin-converting enzyme (ACE) inhibitor, suggested to be more potent than Captopril . The compound is reported to be converted to the active form, Enalaprilat , through hepatic hydrolysis. Studies indicate that Enalapril downregulates the expression of IL-beta, IL-6, and NF-kappaB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1.

Specifications

Sinónimos

Enalaprilat-d5 Sodium Salt | J-006752 | DTXSID10661944 | sodium;(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-(2, 3, 4, 5, 6-pentadeuteriophenyl)propyl]amino]propanoyl]pyrrolidine-2-carboxylate | Enalaprilat D5 Sodium Salt | 1356922-29-6 | Enalaprilic Acid-d5 | Sodium (2

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Sonrisas canónicas: CC(C(=O)N1CCCC1C(=O)[O-])NC(CCC2=CC=CC=C2)C(=O)O.[Na+]
• IUPAC Name: sodium;(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-(2,3,4,5,6-pentadeuteriophenyl)propyl]amino]propanoyl]pyrrolidine-2-carboxylate
• InChIKey: DUDLNVUQNQFAHG-GTIWJLBTSA-M
• INCHI: 1S/C18H24N2O5.Na/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);/q;+1/p-1/t12-,14-,15-;/m0./s1/i2D,3D,4D,6D,7D
• Isómeros SMILES: [2H]C1=C(C(=C(C(=C1[2H])[2H])CC[C@@H](C(=O)O)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)[O-])[2H])[2H].[Na+]
• PubChem CID: 45039129
• Peso molecular: 375.41

Propiedades químicas y físicas

• Solubilidad: Soluble in Methanol and Water
• Punto de fusión (°C): 145-168° C