Epinephrine Bitartrate - Moligand™,≥98% , Adrenergic receptor agonist, CAS No.51-42-3, Adrenergic receptor agonist

CAS: 51-42-3 Cat. No.: E129809 Peso molecular: 333.29 Número EC: 200-097-1

GRADE & PURITY Moligand™, ≥98%

Synonyms

Adrenaline bitartrate | l-Epinephrine bitartrate | L-(–)-Epinephrine-(+)-bitartrate | 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanol | L-Adrenaline Hydrogen Bitartrate | L-Epinephrine Hydrogen Bitartrate

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Descripción general

Epinephrine Bitartrate is an alpha- and beta-adrenergic receptor stimulator.
An α,β-adrenergic receptor agonist.

Specifications

Sinónimos

Adrenaline bitartrate | l-Epinephrine bitartrate | L-(–)-Epinephrine-(+)-bitartrate | 1-(3, 4-Dihydroxyphenyl)-2-(methylamino)ethanol | L-Adrenaline Hydrogen Bitartrate | L-Epinephrine Hydrogen Bitartrate

Especificaciones y pureza

Moligand™, ≥98%

Mecanismos bioquímicos y fisiológicos

L-(-)-Epinephrine-(+)-bitartrate is an α, β-adrenergic receptor agonist. L-(-)-Epinephrine-(+)-bitartrate has positive chronotropic and inotropic effects on cardiac muscle. Its major actions are mediated via activation of AR (adenylate cyclase) to generate

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Protected from light, Argon charged

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

AGONIST

Mecanismo de acción

Adrenergic receptor agonist

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 488179945
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488179945
• Sonrisas canónicas: CNCC(C1=CC(=C(C=C1)O)O)O.C(C(C(=O)O)O)(C(=O)O)O
• IUPAC Name: (2R,3R)-2,3-dihydroxybutanedioic acid;4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
• InChIKey: YLXIPWWIOISBDD-NDAAPVSOSA-N
• INCHI: 1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
• Isómeros SMILES: CNC[C@@H](C1=CC(=C(C=C1)O)O)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
• WGK Alemania: 3
• RTECS: DO3500000
• Peso molecular: 333.29
• Reaxy-Rn: 4117004
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4117004&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Phenols
      • Subclass Benzenediols

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Phenols
• Subclass: Benzenediols
• Intermediate Tree Nodes: Not available
• Direct Parent: Catechols
• Alternative Parents: Aralkylamines 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Dicarboxylic acids and derivatives Benzene and substituted derivatives Secondary alcohols 1,2-aminoalcohols Dialkylamines Organopnictogen compounds Hydrocarbon derivatives Aromatic alcohols
• Molecular Framework: Not available
• Substituents: Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Monocyclic benzene moiety - Dicarboxylic acid or derivatives - 1,2-aminoalcohol - Secondary alcohol - Secondary amine - Secondary aliphatic amine - Alcohol - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Aromatic alcohol - Hydrocarbon derivative - Aromatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as catechols. These are compounds containing a 1,2-benzenediol moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: DMSO 67 mg/mL Water 67 mg/mL Ethanol
• Sensibilidad: Moisture sensitive.Light Sensitive,Air Sensitive,Heat Sensitive
• Índice de refracción: -16.5° (C=2,H2O)
• Punto de fusión (°C): 154 °C
• Peso molecular: 333.290 g/mol
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 6
• Exact Mass: 333.106 Da
• Monoisotopic Mass: 333.106 Da
• Topological Polar Surface Area: 188.000 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 288.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Xiaomin Cao, Miao Qin, Pan Li, Binbin Zhou, Xianghu Tang, Meihong Ge, Liangbao Yang, Jinhuai Liu.  (2018)  Probing catecholamine neurotransmitters based on iron-coordination surface-enhanced resonance Raman spectroscopy label.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2018.04.117]

2. Binbin Zhou, Xiaoyun Li, Xianghu Tang, Pan Li, Liangbao Yang, Jinhuai Liu.  (2017)  Highly Selective and Repeatable Surface-Enhanced Resonance Raman Scattering Detection for Epinephrine in Serum Based on Interface Self-Assembled 2D Nanoparticles Arrays.  ACS Applied Materials & Interfaces,      [PMID:28177221] [10.1021/acsami.6b15205]

3. Shanying Han, Tianyu Du, Hui Jiang, Xuemei Wang.  (2016)  Synergistic effect of pyrroloquinoline quinone and graphene nano-interface for facile fabrication of sensitive NADH biosensor.  BIOSENSORS & BIOELECTRONICS,      [PMID:27156055] [10.1016/j.bios.2016.04.092]