Etanamilato - Moligand™, ≥98% , CAS No.2624-44-4

CAS: 2624-44-4 Cat. No.: E129511 Peso molecular: 263.31 Número EC: 220-090-7

GRADE & PURITY Moligand™, ≥98%

Synonyms

E1145 | 24YL531VOH | Altodor | CHEBI:31563 | Etamsilato (JAN/INN) | HMS1571K11 | CCG-221015 | Dicineno | SR-01000838306-2 | Etamsilato (INN-Español) | AKOS005267176 | Diidroxi-1,4-bencenosulfonato-3-di-etilamonio | DTXCID2025559 | Etamsilato (USAN) | 2

Storage

Conservar a 2-8°C

Shipped In

Hielo húmedo

Descripción general

Agente antifibrinolítico. Aumenta la resistencia endotelial capilar. Favorece la adhesión plaquetaria. Inhibe la desagregación plaquetaria y la biosíntesis y función vasodilatadora de prostaglandinas. Aumenta la expresión de la membrana de la P-selectina. Muestra efectos angioprotectores y proagregantes in vivo. Activo por vía oral.

Specifications

Sinónimos

E1145 | 24YL531VOH | Altodor | CHEBI:31563 | Etamsilato (JAN/INN) | HMS1571K11 | CCG-221015 | Dicineno | SR-01000838306-2 | Etamsilato (INN-Español) | AKOS005267176 | Diidroxi-1, 4-bencenosulfonato-3-di-etilamonio | DTXCID2025559 | Etamsilato (USAN) | 2

Especificaciones y pureza

Moligand™, ≥98%

Mecanismos bioquímicos y fisiológicos

Agente antifibrinolítico. Aumenta la resistencia endotelial capilar. Favorece la adhesión plaquetaria. Inhibe la desagregación plaquetaria y la biosíntesis y función vasodilatadora de prostaglandinas. Aumenta la expresión de la membrana de la P-selectina.

Condiciones de almacenamiento de almacenamiento

Conservar a 2-8°C

Enviado en

Hielo húmedo

Grado

Moligand™

Nota

Siempre que sea posible, prepare y utilice las soluciones el mismo día. Sin embargo, si necesita preparar soluciones madre con antelación, le recomendamos que almacene la solución como alícuotas en viales herméticamente cerrados a -20°C. Por lo general, podrán utilizarse durante un mes. Antes de su uso, y antes de abrir el vial, le recomendamos que deje que el producto se equilibre a temperatura ambiente durante al menos 1 hora. ¿Necesita más consejos sobre solubilidad, uso y manipulación? Visite nuestra página de preguntas frecuentes (FAQ) para obtener más información.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 504752832
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504752832
• Sonrisas canónicas: CCNCC.C1=CC(=C(C=C1O)S(=O)(=O)O)O
• IUPAC Name: 2,5-dihydroxybenzenesulfonic acid;N-ethylethanamine
• InChIKey: HBGOLJKPSFNJSD-UHFFFAOYSA-N
• INCHI: 1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3
• Isómeros SMILES: CCNCC.C1=CC(=C(C=C1O)S(=O)(=O)O)O
• RTECS: DB6145000
• Peso molecular: 263.31
• Reaxy-Rn: 4166074
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4166074&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Benzene and substituted derivatives
      • Subclass Benzenesulfonic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Benzene and substituted derivatives
• Subclass: Benzenesulfonic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzenesulfonic acids and derivatives
• Alternative Parents: Benzenesulfonyl compounds 1-sulfo,2-unsubstituted aromatic compounds Hydroquinones 1-hydroxy-2-unsubstituted benzenoids Sulfonyls Organosulfonic acids Dialkylamines Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: Benzenesulfonate - Arylsulfonic acid or derivatives - Benzenesulfonyl group - 1-sulfo,2-unsubstituted aromatic compound - Hydroquinone - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Sulfonyl - Organosulfonic acid - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Secondary aliphatic amine - Secondary amine - Amine - Hydrocarbon derivative - Organic oxide - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as benzenesulfonic acids and derivatives. These are organic compounds containing a sulfonic acid or a derivative thereof that is linked to a benzene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

Discover Target: CYP2C19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)

Discover Target: HIF1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

Discover Target: HPGD

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasma (328 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: DMSO 53 mg/mL Water 53 mg/mL Ethanol <1 mg/mL
• Sensibilidad: light and moisture sensitive
• Punto de fusión (°C): 130 °C
• Peso molecular: 263.310 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 263.083 Da
• Monoisotopic Mass: 263.083 Da
• Topological Polar Surface Area: 115.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 252.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Fang-Ning Qiu, Qiao-Lei Wang, Ping Li, Qiu-Yi Pu, Hui-Jun Li.  (2025)  Revealing the chemical and pharmacological individualities of two pharmacopoeial Paris species for the purpose of precise medication.  JOURNAL OF ETHNOPHARMACOLOGY,      [PMID:40796021] [10.1016/j.jep.2025.120402]

2. Ye Fan, Ming Lu, Junyi Huang, Ling Huang, Huade Zheng.  (2025)  Radiopaque PVA–Based Beads Loaded With Doxorubicin and Etamsylate for Transarterial Chemoembolization.  ADVANCES IN POLYMER TECHNOLOGY,  2025  (1): (9396134).  [PMID:] [10.1155/adv/9396134]