Name: Ethyl 3,4-Dihydroxycinnamate - ≥97% , CAS No.66648-50-8
Brand: Aladdin Scientific
SKU: E341244
Availability: InStock

Ethyl 3,4-Dihydroxycinnamate - ≥97% , CAS No.66648-50-8

CAS: 66648-50-8 Cat. No.: E341244 Peso molecular: 208.2 Número EC: 676-772-3

Saltar al final de la galería de imágenes

Ethyl 3,4-Dihydroxycinnamate - ≥97% CAS No(66648-50-8) by Aladdin Scientific

Saltar al comienzo de la galería de imágenes

Disponible para pedir

GRADE & PURITY ≥97%

Synonyms

4gqq | NSC619661 | NSC-619661 | ethyl 3-(3,4-dihydroxyphenyl)prop-2-enoate | (E)-ethyl caffeate | AC-34380 | HY-N6966 | 2-oxo-3-(phosphonooxy)-Propanoic acid | Caffeic acid ethyl ester | DTXSID201336725 | (E)-Ethyl Dihydroxycinnamate | 3-(3,4-Dihydroxy-ph

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Size

Estado

Price

Qty

250mg

E341244-250mg

8-12 wks(?)

15,90US$

E341244-1g

8-12 wks(?)

24,90US$

39,90US$
Guardar 15,00 US$ (37.59%)

E341244-5g

8-12 wks(?)

85,90US$

129,90US$
Guardar 44,00 US$ (33.87%)

25g

E341244-25g

8-12 wks(?)

328,90US$

399,90US$
Guardar 71,00 US$ (17.75%)

Enter a quantity for the sizes you want to add.

Bulk / Custom

♡ Lista de deseos ⇅ Añadir para comparar ⎙ Print page

Descripción general Specifications Propiedades del producto Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas

🧪

Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Ethyl 3,4-Dihydroxycinnamate is an ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol.Natural product derived from plant source.

Ethyl 3,4-dihydroxycinnamate shows anti-inflammatory, immunomodulatory, and anti-carcinogenic properties. It is a potent and specific inhibitor of NF-κB and its downstream inflammatory mediators: NOS2 (inducible nitric oxide synthase; NOS; NOS II), Cox-2 (cyclooxygenase-2), and prostaglandin E2 (PGE2). Ethyl 3,4-Dihydroxycinnamate prevents DNA single-strand breaks caused by H2O2.

Application

Used for compound screening libraries, metabolomics, phytochemistry, and drug research.

Specifications

Sinónimos

4gqq | NSC619661 | NSC-619661 | ethyl 3-(3, 4-dihydroxyphenyl)prop-2-enoate | (E)-ethyl caffeate | AC-34380 | HY-N6966 | 2-oxo-3-(phosphonooxy)-Propanoic acid | Caffeic acid ethyl ester | DTXSID201336725 | (E)-Ethyl Dihydroxycinnamate | 3-(3, 4-Dihydroxy-ph

Especificaciones y pureza

≥97%

Mecanismos bioquímicos y fisiológicos

Ethyl dihydroxycinnamate exhibits potent cytotoxicity, inhibits COX-2 and P-hydroxybenzoic acid, both involved in inflammation and cytokine synthesis. It demonstrates antibacterial efficacy against MRSA and Bacillus subtilis and inhibits cancer cell growt

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥97%

Propiedades del producto

pKa	pKₐ: 8.71 (Predicted)

Nombres e identificadores

Sonrisas canónicas	CCOC(=O)C=CC1=CC(=C(C=C1)O)O
IUPAC Name	ethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
InChIKey	WDKYDMULARNCIS-GQCTYLIASA-N
INCHI	1S/C11H12O4/c1-2-15-11(14)6-4-8-3-5-9(12)10(13)7-8/h3-7,12-13H,2H2,1H3/b6-4+
Isómeros SMILES	CCOC(=O)/C=C/C1=CC(=C(C=C1)O)O
Peso molecular	208.2
Reaxy-Rn	2646303
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2646303&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Phenylpropanoids and polyketides
  - Clase Cinnamic acids and derivatives
    - Subclass Hydroxycinnamic acids and derivatives

Kingdom	Organic compounds
Superclass	Phenylpropanoids and polyketides
Clase	Cinnamic acids and derivatives
Subclass	Hydroxycinnamic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Coumaric acids and derivatives
Alternative Parents	Cinnamic acid esters Styrenes Catechols Fatty acid esters 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Enoate esters Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Coumaric acid or derivatives - Cinnamic acid ester - Catechol - Styrene - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Fatty acid ester - Fatty acyl - Benzenoid - Monocyclic benzene moiety - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Carboxylic acid ester - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Organic oxide - Aromatic homomonocyclic compound
Descripción	This compound belongs to the class of organic compounds known as coumaric acids and derivatives. These are aromatic compounds containing Aromatic compounds containing a cinnamic acid moiety (or a derivative thereof) hydroxylated at the C2 (ortho-), C3 (meta-), or C4 (para-) carbon atom of the benzene ring.
External Descriptors	hydroxycinnamic acid
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estructura 3D

Objetivos asociados (humanos)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

Discover Target: ALOX5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BeWo (124 Activities)

Lot Number	Certificate Type	Fecha	Articulo
B2604219	Certificate of Analysis	Jan 16, 2026	E341244
B2604220	Certificate of Analysis	Jan 16, 2026	E341244
B2604221	Certificate of Analysis	Jan 16, 2026	E341244
B2604224	Certificate of Analysis	Jan 16, 2026	E341244

Sensibilidad	light sensitive
Índice de refracción	n20D1.61 (Predicted)
Punto de ebullición (°C)	376.98° C at 760 mmHg (Predicted)
Punto de fusión (°C)	142.0°C-148.0°C
Peso molecular	208.210 g/mol
XLogP3	2.600
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	208.074 Da
Monoisotopic Mass	208.074 Da
Topological Polar Surface Area	66.800 Å²
Heavy Atom Count	15
Formal Charge	0
Complexity	237.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

Ethyl 3,4-Dihydroxycinnamate - ≥97% , CAS No.66648-50-8

Why this grade

Storage & shipping

Quality documents

Literature proof

Descripción general

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reseñas de cliente

View related series