Treatment of the Reformatsky reagent with aldehydes and ketones affords 2,2-difluoro-3-hydroxy esters. Please enquire for references and other data for this item.
Usually used in the preparation of substituted ethyl 2′-pyridyldifluoroacetates,4-alkoxymethyl- and 4-aryloxymethyl-3,3-difluoropiperidines,α,α-difluoro-β-lactams,mono- and difluoromethylated phenanthridine derivatives.
| Pubchem Sid | 488184362 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488184362 |
| Sonrisas canónicas | CCOC(=O)C(F)(F)Br |
| IUPAC Name | ethyl 2-bromo-2,2-difluoroacetate |
| InChIKey | IRSJDVYTJUCXRV-UHFFFAOYSA-N |
| INCHI | 1S/C4H5BrF2O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3 |
| Isómeros SMILES | CCOC(=O)C(F)(F)Br |
| WGK Alemania | 3 |
| Número ONU | 2924 |
| Peso molecular | 202.98 |
| Beilstein | 1906095 |
| Reaxy-Rn | 1906095 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1906095&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Clase | Carboxylic acids and derivatives |
| Subclass | Alpha-halocarboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Alpha-halocarboxylic acid derivatives |
| Alternative Parents | Carboxylic acid esters Monocarboxylic acids and derivatives Organofluorides Organobromides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides Alkyl bromides |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Alpha-halocarboxylic acid derivative - Carboxylic acid ester - Monocarboxylic acid or derivatives - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organofluoride - Organobromide - Organohalogen compound - Carbonyl group - Alkyl halide - Alkyl fluoride - Alkyl bromide - Aliphatic acyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as alpha-halocarboxylic acid derivatives. These are carboxylic acid derivatives containing a halogen atom bonded to the alpha carbon atom. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 H2428379 | Certificate of Analysis | Jun 08, 2026 | E107843 |
| H2428378 | Certificate of Analysis | Jun 08, 2026 | E107843 |
| H2428377 | Certificate of Analysis | Jun 08, 2026 | E107843 |
| D2310308 | Certificate of Analysis | Jan 20, 2025 | E107843 |
| D2310314 | Certificate of Analysis | Jan 07, 2025 | E107843 |
| D2310330 | Certificate of Analysis | Jan 07, 2025 | E107843 |
| J2520199 | Certificate of Analysis | Jul 27, 2024 | E107843 |
| E2413328 | Certificate of Analysis | Apr 29, 2024 | E107843 |
| E2413329 | Certificate of Analysis | Apr 29, 2024 | E107843 |
| K2125509 | Certificate of Analysis | Aug 21, 2023 | E107843 |
| K2125515 | Certificate of Analysis | Aug 21, 2023 | E107843 |
| K2125523 | Certificate of Analysis | Aug 21, 2023 | E107843 |
| F1905106 | Certificate of Analysis | Feb 07, 2023 | E107843 |
| H1506019 | Certificate of Analysis | Feb 03, 2023 | E107843 |
| B2102050 | Certificate of Analysis | Dec 12, 2022 | E107843 |
| J2030090 | Certificate of Analysis | Aug 15, 2022 | E107843 |
| J2030089 | Certificate of Analysis | Aug 15, 2022 | E107843 |
| Solubilidad | Soluble in most organic solvents. |
|---|---|
| Índice de refracción | 1.387 |
| Punto de inflamación (°F) | 69.8 °F |
| Punto de inflamación (°C) | 21 ℃ |
| Punto de ebullición (°C) | 112°C |
| Peso molecular | 202.980 g/mol |
| XLogP3 | 1.600 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 201.944 Da |
| Monoisotopic Mass | 201.944 Da |
| Topological Polar Surface Area | 26.300 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 115.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
