Induced differentiation of human embryonic stem cells
Induced differentiation of human embryonic stem cells
Embryonic stem cells are cells with a self-renewal and totipotent differentiation ability, capable of developing and differentiating into all tissues and organs of the adult body, and are the most ideal model for in vitro studies of developmental regulatory mechanisms, as well as the most ideal seed cells for use in stem cell therapy of human diseases and organ and tissue transplantation.
Principle
The basic principle of induced differentiation of human embryonic stem cells is to induce differentiation of embryonic stem cells into tissue-specific cells by adding different growth factors and molecules affecting the corresponding signaling pathways at different periods of time in vitro, based on the results of the study of the activation of growth factors and stage-specific signaling pathways that are essential for the development of various tissues in the course of embryonic development.
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