Artículos por tema "Chiral amide"

1. The Methodological Value of Boc-Oxyma: Low-Racemization Coupling, Route Continuity, and Extended Applications
   posted this at 30 mar 2026

   1
   The full name of Boc-Oxyma is ethyl 2-(tert-butoxycarbonyloxyimino)-2-cyanoacetate, i.e., 2-(tert-butoxycarbonyloxyimino)-2-cyanoacetic acid ethyl ester. Based on the currently available published literature, Boc-Oxyma has developed three main lines of application together with one bridging use ...
2. From “High Yield” to “Configuration Retention”: Activation-Stage Risks, Route Differences, and Selection Principles for Coupling Systems
   posted this at 29 mar 2026

   2
   In amide and peptide synthesis, whether a bond can be formed is certainly important. However, for amino acids, peptide fragments, and chiral carboxylic acid substrates containing an α-stereogenic center, another issue often plays an equally decisive role in determining the quality of the ...