The Angiopoietin-TIE2 signaling pathway is an important axis regulating vascular maturation, endothelial barrier stability, vascular inflammatory responses, and pathological vascular remodeling.
Adrenomedullin (adrenomedullin, ADM) is an endogenous peptide with potent vasoactive and cytoprotective properties, first isolated and identified from human pheochromocytoma tissue.
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