The VEGF (vascular endothelial growth factor) signaling pathway is one of the central molecular networks in angiogenesis research. Its role is not limited to promoting endothelial cell proliferation.
Angiogenesis is the process by which new microvessels form from an existing vascular network. It is jointly regulated by soluble pro-angiogenic and anti-angiogenic factors, cytokines, protease systems, extracellular matrix (ECM) components, and adhesion molecules. Angiogenesis is ...
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