for silylations

Silylation Reagents: Selection & Practical Handbook

Silylation replaces the labile hydrogens in a molecule (–OH, –COOH, –NH₂, =NH, –SH, etc.) with silyl groups—most commonly trimethylsilyl (TMS) or tert-butyldimethylsilyl (TBDMS/tBDMS). The resulting derivatives are more volatile, less polar, and more thermally robust, which improves ...